Wise, Sarah K Damask, Cecelia Roland, Lauren T Ebert, Charles Levy, Joshua M Lin, Sandra Luong, Amber Rodriguez, Kenneth Sedaghat, Ahmad R Toskala, Elina
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Published in
International forum of allergy & rhinology
In the 5 years that have passed since the publication of the 2018 International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR-Allergic Rhinitis 2018), the literature has expanded substantially. The ICAR-Allergic Rhinitis 2023 update presents 144 individual topics on allergic rhinitis (AR), expanded by over 40 topics from the...
losada, maría mangas robles, leonardo romero melero, alejandro mendoza megías, irene garcía torres, amós villanueva zumarán, puy garrastachu chollet, xavier boulvard lopci, egesta lasanta, rafael ramírez delgado bolton, roberto c.
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Immunotherapy is based on manipulation of the immune system in order to act against tumour cells, with growing evidence especially in melanoma patients. The challenges faced by this new therapeutic tool are (i) finding valid evaluation criteria for response assessment; (ii) knowing and distinguishing between “atypical” response patterns; (iii) usin...
schepisi, giuseppe gianni, caterina palleschi, michela bleve, sara casadei, chiara lolli, cristian ridolfi, laura martinelli, giovanni de giorgi, ugo
Breast cancer represents one of the most common tumor histologies. To date, based on the specific histotype, different therapeutic strategies, including immunotherapies, capable of prolonging survival are used. More recently, the astonishing results that were obtained from CAR-T cell therapy in haematological neoplasms led to the application of thi...
Bertaglia, Valentina Morelli, Anna Maria Solinas, Cinzia Aiello, Marco Maria Manunta, Silvia Denaro, Nerina Tampellini, Marco Scartozzi, Mario Novello, Silvia
Published in
Critical reviews in oncology/hematology
Patients with a diagnosis of lung cancer are often vulnerable to infection, and the risk is increased by tumor-associated immunosuppression and the effects of the treatments. Historically, links between the risk of infection and cytotoxic chemotherapy due to neutropenia and respiratory syndromes are well established. The advent of tyrosine kinase i...
Wu, Qihui Tian, Ruotong Liu, Jiaxin Ou, Chunlin Li, Yimin Fu, Xiaodan
Published in
Frontiers in Immunology
Background Dysregulation of chromatin regulators (CRs) can perturb the tumor immune microenvironment, but the underlying mechanism remains unclear. We focused on uterine corpus endometrial carcinoma (UCEC) and used gene expression data from TCGA-UCEC to investigate this mechanism. Methods We used weighted gene co-expression network analysis (WGCNA)...
Ibrahim, Sherif Abdelaziz Yip, George W. Götte, Martin
Published in
Frontiers in Oncology
Matas-Céspedes, Alba Lapointe, Jean-Martin Elder, Matthew J. Browne, Gareth J. Dovedi, Simon J. de Haan, Lolke Maguire, Shaun Stebbings, Richard
Published in
Frontiers in Immunology
Introduction Humanized mice are emerging as valuable models to experimentally evaluate the impact of different immunotherapeutics on the human immune system. These immunodeficient mice are engrafted with human cells or tissues, that then mimic the human immune system, offering an alternative and potentially more predictive preclinical model. Immuno...
Wang, Yeping Ren, Xiaoyan Shen, Yu Hua, Yi Xu, Lu Zhang, Weiran Sheng, Guoxia Jiang, Peifang Yuan, Zhefeng Liu, Liu
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Published in
Frontiers in Pediatrics
Objective To explore the clinical characteristics of pediatric anti-gamma-aminobutyric acid-B receptor (GABABR) encephalitis to enhance the understanding and improve the diagnostic and therapeutic strategies for this disease.Methods We report a rare case of a female pediatric patient with anti-GABABR encephalitis who was treated at the Children's H...
cannone, giorgio comacchio, giovanni maria pasello, giulia faccioli, eleonora schiavon, marco dell’amore, andrea mammana, marco rea, federico
Non-small cell lung cancer (NSCLC) is still one of the leading causes of death worldwide. This is mostly because the majority of lung cancers are discovered in advanced stages. In the era of conventional chemotherapy, the prognosis of advanced NSCLC was grim. Important results have been reported in thoracic oncology since the discovery of new molec...
Deng, Ya-Ya Zhang, Xin-Yue Zhu, Peng-Fei Lu, Hong-Rui Liu, Qian Pan, Shuang-Yue Chen, Zhe-Ling Yang, Liu
Published in
Frontiers in Oncology
Background Fruquintinib and regorafenib have been approved for the third-line therapy of metastatic colorectal cancer (mCRC) in China. However, at present, there is a lack of head-to-head clinical trials on the comparison of efficacy and safety between the two drugs. Materials and methods The data of patients with mCRC who were treated with fruquin...
