Wang, Gang Qu, Fangfang Zhou, Jincai Zhu, Bingye Gao, Yulong
Published in
Cell cycle (Georgetown, Tex.)
This study was used to assess THBS3's overall survival (OS) prognostic values in clear cell renal cell carcinoma (ccRCC) as well as to determine the LncRNA/RNA binding protein (RBP)/THBS3 interactions. Clinical data and RNA sequencing data were gathered from the TCGA dataset. Significant pathways associated with THBS3 were identified by gene set en...
Wang, Yi Zhang, Xinyu Chen, Yinhao Zhu, Bingye Xing, Qianwei
Published in
Andrology
Currently, patients with diabetic erectile dysfunction (DMED) were not satisfied with the effects of first-line phosphodiesterase type 5 inhibitors (PDE5Is). Hence, this paper was designed to mine hub biomarkers in DMED and explore its potential mechanisms. Gene expression matrix of DMED was downloaded from the gene expression omnibus (GEO; GSE2457...
Jeon, Hwi Seong Jang, Eunjeong Kim, Jinwoo Kim, Seu Ha Lee, Myoung-Hoon Nam, Myung Hee Tobimatsu, Yuki Park, Ohkmae K
Published in
Autophagy
The evolutionary plant-pathogen arms race has equipped plants with the immune system that can defend against pathogens. Pattern-triggered immunity and effector-triggered immunity are two major branches of innate immunity that share immune responses, including oxidative bursts, transcriptional reprogramming, and cell wall modifications such as ligni...
Arterburn, Jeffrey B. Prossnitz, Eric R.
The actions of estrogens and related estrogenic molecules are complex and multifaceted in both sexes. A wide array of natural, synthetic, and therapeutic molecules target pathways that produce and respond to estrogens. Multiple receptors promulgate these responses, including the classical estrogen receptors of the nuclear hormone receptor family (e...
Nagy, Ádám Dombi, József Fülep, Martin Patrik Rudics, Emese Hompoth, Emőke Adrienn Szabó, Zoltán Dér, András Búzás, András Viharos, Zsolt János Hoang, Anh Tuan
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Published in
Sensors (Basel, Switzerland)
(1) Background and Goal: Several studies have investigated the association of sleep, diurnal patterns, and circadian rhythms with the presence and with the risk states of mental illnesses such as schizophrenia and bipolar disorder. The goal of our study was to examine actigraphic measures to identify features that can be extracted from them so that...
Lytle, Jason R Price, Tara Crouse, Stephen F Smith, Dana R Walzem, Rosemary L Smith, Stephen B
Published in
Nutrients
We hypothesized that consumption of high-fat (HF) ground beef (24% fat) would not affect plasma concentrations of high-density lipoprotein cholesterol (HDL-C) or low-density lipoprotein (LDL-C), whereas low-fat (LF) ground beef (5% fat) would decrease HDL-C and LDL-C concentrations. In a randomized 2-period crossover, controlled feeding trial, 25 m...
Schnizer, Clara Andreas, Nico Vivas, Wolfgang Kamradt, Thomas Baier, Michael Kiehntopf, Michael Glöckner, Stefan Scherag, André Löffler, Bettina Kolanos, Steffi
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Published in
Frontiers in Immunology
Understanding persistent cellular and humoral immune responses to SARS-CoV-2 will be of major importance to terminate the ongoing pandemic. Here, we assessed long-term immunity in individuals with mild COVID-19 up to 1 year after a localized SARS-CoV-2 outbreak. CoNAN was a longitudinal population-based cohort study performed 1.5 months, 6 months, ...
Pereiro, Patricia Rey-Campos, Magalí Figueras, Antonio Novoa, Beatriz
Published in
Frontiers in Immunology
In this work, we analysed the transcriptome and metatranscriptome profiles of zebrafish exposed to an environmental concentration of the two antibiotics most frequently detected in European inland surface water, sulfamethoxazole (SMX) and clarithromycin (CLA). We found that those animals exposed to antibiotics (SMX+CLA) for two weeks showed a highe...
Khan, Muhammad Zahoor Liu, Shuai Ma, Yulin Ma, Mei Ullah, Qudrat Khan, Ibrar Muhammad Wang, Jingjun Xiao, Jianxin Chen, Tianyu Khan, Adnan
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Published in
Frontiers in Immunology
Overproduction of reactive oxygen species (ROS) is a well-known phenomenon experienced by ruminants, especially during the transition from late gestation to successful lactation. This overproduction of ROS may lead to oxidative stress (OS), which compromises the immune and anti-inflammatory systems of animals, thus predisposing them to health issue...
Matthus, Elsa Ning, Youzheng Shafiq, Fahad Davies, Julia M.
Published in
Frontiers in Plant Science
Phosphate deprivation compromises plant productivity and modulates immunity. DAMP signalling by extracellular ATP (eATP) could be compromised under phosphate deprivation by the lowered production of cytosolic ATP and the need to salvage eATP as a nutritional phosphate source. Phosphate-starved roots of Arabidopsis can still sense eATP, indicating r...