Jaggessar, Alka Velic, Amar Yarlagadda, Prasad KDV Spann, Kirsten
Published in
ACS Biomaterials Science & Engineering
The rapid emergence and global spread of the COVID-19 causing Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and its subsequent mutated strains has caused unprecedented health, economic, and social devastation. Respiratory viruses such as SARS-CoV-2 can be transmitted through both direct and indirect channels, including aerosol respir...
Dijkman, Ronald Verma, Abhishek Kumar Selvaraj, Muneeswaran Ghimire, Roshan Gad, Hans Henrik Hartmann, Rune More, Sunil Perlman, Stanley Thiel, Volker Channappanavar, Rudragouda
...
Published in
Journal of Virology
Effective broad-spectrum antivirals are critical to prevent and control emerging human coronavirus (hCoV) infections. Despite considerable progress made toward identifying and evaluating several synthetic broad-spectrum antivirals against hCoV infections, a narrow therapeutic window has limited their success. Enhancing the endogenous interferon (IF...
gyun, ji uk hwan
Polymerase chain reaction has gained attention since the outbreak of novel coronavirus in 2019. Due to its high specificity and capability for early detection, it is considered a standard method for the diagnosis of infectious diseases. However, the conventional thermocyclers used for nucleic acid amplification are not suitable for point-of-care te...
Sasaki, Shota Osana, Shion Kubota, Takahiro Yamaya, Mutsuo Nishimura, Hidekazu Nagatomi, Ryoichi Kaneko, Toshiro
Published in
Journal of Physics D: Applied Physics
The recent global pandemic of Corona Virus Disease-19 has impacted all aspects of society, producing a growing demand for a powerful virus inactivation method. To assess a potential and mechanism of human coronavirus inactivation using atmospheric pressure plasma (APP) technology, replication of a human coronavirus (HCoV-229E) after He + H2O APP pl...
lourenco, christiane
Background: Given that reports have suggested SARS-CoV-2 can be transmitted via conjunctiva, the ability of contact lens (CL) care products to reduce the infectiousness of two seasonal human coronavirus (HCoV) (HCoV-229E and HCoV-OC43) surrogates for SARS-CoV-2 was investigated. Methods: Biotrue and Boston Simplus (Bausch&Lomb), OPTI-FREE Puremoist...
Jo, Kyo Jin Choi, Soo-Han Oh, Chi Eun Kim, HyeonA Choi, Bong Seok Jo, Dae Sun Park, Su Eun
Published in
Frontiers in Pediatrics
Background Human coronaviruses (HCoVs) are associated with upper respiratory tract infections. Although studies have analyzed the clinical and epidemiological characteristics of HCoV-associated infections, no multi-center studies have been conducted in Korean children. We aimed to describe the epidemiology and clinical characteristics of HCoV-assoc...
duan;, lu xu qianyu
The coronavirus disease 2019 (COVID-19) pandemic caused by infection of SARS-CoV-2 and its variants has posed serious threats to global public health, thus calling for the development of potent and broad-spectrum antivirals. We previously designed and developed a peptide-based pan-coronavirus (CoV) fusion inhibitor, EK1, which is effective against ...
Abulikemu, Mutalifu Tabrizi, Bita E. A. Ghobadloo, Shahrokh M. Mofarah, Hamed M. Jabbour, Ghassan E.
Published in
ACS Applied Nano Materials
The Coronavirus disease 2019 (COVID-19) global outbreak and its continued growth and mutation into various forms emphasize the need for effective disinfectants to assist in the reduction of the virus’s spread from individual to individuals and community to communities through various modes, including coughing, sneezing, touching of contaminated sur...
kim;, in ho oh minwoo
In spite of the large number of repositioned drugs and direct-acting antivirals in clinical trials for the management of the ongoing COVID-19 pandemic, there are few cost-effective therapeutic options for severe acute respiratory syndrome (SARS) coronavirus 2 (SCoV2) infection. In this paper, we show that xanthorrhizol (XNT), a bisabolane-type sesq...
Bayat, Vafa Phelps, Steven Ryono, Russell Lee, Chong Parekh, Hemal Mewton, Joel Sedghi, Farshid Etminani, Payam Holodniy, Mark
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
With the limited availability of testing for the presence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus and concerns surrounding the accuracy of existing methods, other means of identifying patients are urgently needed. Previous studies showing a correlation between certain laboratory tests and diagnosis suggest an alter...
