Sermek, Antonio Feliciello, Isidoro Ugarković, Đurđica
Published in
International Journal of Molecular Sciences
In the flour beetle, Tribolium castaneum (peri)centromeric heterochromatin is mainly composed of a major satellite DNA TCAST1 interspersed with minor satellites. With the exception of heterochromatin, clustered satellite repeats are found dispersed within euchromatin. In order to uncover a possible satellite DNA function within the beetle genome, w...
Ahmad, Syed Farhan Singchat, Worapong Jehangir, Maryam Suntronpong, Aorarat Panthum, Thitipong Malaivijitnond, Suchinda Srikulnath, Kornsorn
Published in
Cells
A substantial portion of the primate genome is composed of non-coding regions, so-called “dark matter”, which includes an abundance of tandemly repeated sequences called satellite DNA. Collectively known as the satellitome, this genomic component offers exciting evolutionary insights into aspects of primate genome biology that raise new questions a...
Ruault, Myriam Scolari, Vittore Lazar-Stefanita, Luciana Hocher, Antoine Loïodice, Isabelle Noûs, Camille Koszul, Romain Taddei, Angela
Posté dans BioRxiv le 29 juin 2020
Leicher, Rachel Ge, Eva J. Lin, Xingcheng Reynolds, Matthew J. Xie, Wenjun Walz, Thomas Zhang, Bin Muir, Tom W. Liu, Shixin
Published in
Proceedings of the National Academy of Sciences of the United States of America
Polycomb repressive complex 2 (PRC2) installs and spreads repressive histone methylation marks on eukaryotic chromosomes. Because of the key roles that PRC2 plays in development and disease, how this epigenetic machinery interacts with DNA and nucleosomes is of major interest. Nonetheless, the mechanism by which PRC2 engages with native-like chroma...
Kasinathan, Bhavatharini Colmenares, Serafin U McConnell, Hannah Young, Janet M Karpen, Gary H Malik, Harmit S
Contrary to dogma, evolutionarily young and dynamic genes can encode essential functions. We find that evolutionarily dynamic ZAD-ZNF genes, which encode the most abundant class of insect transcription factors, are more likely to encode essential functions in Drosophila melanogaster than ancient, conserved ZAD-ZNF genes. We focus on the Nicknack ZA...
Kasinathan, Bhavatharini Colmenares, Serafin U 3rd McConnell, Hannah Young, Janet M Karpen, Gary H Malik, Harmit S
Published in
eLife
Contrary to dogma, evolutionarily young and dynamic genes can encode essential functions. We find that evolutionarily dynamic ZAD-ZNF genes, which encode the most abundant class of insect transcription factors, are more likely to encode essential functions in Drosophila melanogaster than ancient, conserved ZAD-ZNF genes. We focus on the Nicknack ZA...
Feliciello, Isidoro Pezer, Željka Kordiš, Dušan Bruvo Mađarić, Branka Ugarković, Đurđica
Published in
Genome biology and evolution
Major human alpha satellite DNA repeats are preferentially assembled within (peri)centromeric regions but are also dispersed within euchromatin in the form of clustered or short single repeat arrays. To study the evolutionary history of single euchromatic human alpha satellite repeats (ARs), we analyzed their orthologous loci across the primate gen...
IDRISSOU, MOUHAMED BOISNIER, TIPHANIE SANCHEZ, ANNA KHOUFAF, FATMA ZOHRA HOUFAF PENAULT-LLORCA, FREDERIQUE BIGNON, YVES-JEAN BERNARD-GALLON, DOMINIQUE
Published in
Cancer Genomics & Proteomics
Background/Aim: In breast cancer, initiation of carcinogenesis leads to epigenetic dysregulation, which can lead for example to the loss of the heterochromatin skeleton SUV39H1/H3K9me3/HP1 or the supposed secondary skeleton TIP60/P400/H4K12ac/BRD (2/4), which allows the maintenance of chromatin integrity and plasticity. This study investigated the ...
Thakur, Jitendra Henikoff, Steven
Published in
Biochemical Society transactions
RNA plays a well-established architectural role in the formation of membraneless interchromatin nuclear bodies. However, a less well-known role of RNA is in organizing chromatin, whereby specific RNAs have been found to recruit chromatin modifier proteins. Whether or not RNA can act as an architectural molecule for chromatin remains unclear, partly...
Gorobeyko, Uliana V. Kartavtseva, Irina V. Sheremetyeva, Irina N. Kazakov, Denis V. Guskov, Valentin Yu.
Published in
Comparative Cytogenetics
The DNA-barcoding and chromosomal study of the eastern water bat, Myotis petax Hollister, 1912, from the earlier unexplored localities in the Russian Far East are carried out. The COI barcoding obtained for 18 from a total of 19 individuals captured in five localities in the Russian Far East showed the low nucleotide variability with the prevalence...
