Wright, S P Dawkins, T G Eves, N D Shave, R Tedford, R J Mak, S
Published in
American journal of physiology. Heart and circulatory physiology
With each heartbeat, the right ventricle (RV) inputs blood into the pulmonary vascular (PV) compartment, which conducts blood through the lungs at low pressure and concurrently fills the left atrium (LA) for output to the systemic circulation. This overall hemodynamic function of the integrated RV-PV-LA unit is determined by complex interactions be...
Davidson, Laura J Chow, Kimberly Y Jivan, Arif Prenner, Stuart B Cohen, Elaine R Schimmel, Daniel R McGaghie, William C Barsuk, Jeffrey H Wayne, Diane B Sweis, Ranya N
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Published in
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Medical procedures are traditionally taught informally at patients' bedside through observation and practice using the adage "see one, do one, teach one." This lack of formalized training can cause trainees to be unprepared to perform procedures independently. Simulation based education (SBE) increases competence, reduces complications, and decreas...
Xiong, Zhuxiang Yuan, Ding Wang, Jiarong Zheng, Tinghui Fan, Yubo
Published in
Computer methods in biomechanics and biomedical engineering
Currently, the clinical classification of the severity of renal artery stenosis (RAS) solely depends on the degree of stenosis. In addition, when the stenosis degree is between 50% and 70%, the clinical strategy is decided based on whether the RAS is hemodynamically significant. In this study, the influence of RAS morphological parameters on hemody...
Cetin, Elif Ho Cetin, Mehmet S Könte, Hasan C Ocak, Kadir Yaman, Nezaket M Hepsen, Sema Ozeke, Ozcan Temizhan, Ahmet Topaloglu, Serkan Aras, Dursun
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Published in
Biomarkers in medicine
Background: We aimed to assess the association of triiodothyronine (T3) hormone with invasive hemodynamic parameters and all-cause mortality in heart failure with reduced ejection fraction (HFrEF). Results: About 483 HFrEF patients were enrolled. Patients with the lowest T3 tertile had advanced New York Heart Association (NYHA) classes, had higher ...
Kaczmarz, Stephan Göttler, Jens Petr, Jan Hansen, Mikkel Bo Mouridsen, Kim Zimmer, Claus Hyder, Fahmeed Preibisch, Christine
Published in
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Improved understanding of complex hemodynamic impairments in asymptomatic internal carotid artery stenosis (ICAS) is crucial to better assess stroke risks. Multimodal MRI is ideal for measuring brain hemodynamics and has the potential to improve diagnostics and treatment selections. We applied MRI-based perfusion and oxygenation-sensitive imaging i...
Rivera-Rivera, Leonardo A Cody, Karly A Eisenmenger, Laura Cary, Paul Rowley, Howard A Carlsson, Cynthia M Johnson, Sterling C Johnson, Kevin M
Published in
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Clinical evidence shows vascular factors may co-occur and complicate the expression of Alzheimer's disease (AD); yet, the pathologic mechanisms and involvement of different compartments of the vascular network are not well understood. Diseases such as arteriosclerosis diminish vascular compliance and will lead to arterial stiffness, a well-establis...
Pavlek, Leeann R. Mueller, Clifford Jebbia, Maria R. Kielt, Matthew J. Fathi, Omid
Published in
Frontiers in Pediatrics
With advances in neonatal care, survival of premature infants at the limits of viability has improved significantly. Despite these improvement in mortality, infants born at 22–24 weeks gestation are at a very high risk for short- and long-term morbidities associated with prematurity. Many of these diseases have been attributed to abnormalities of t...
Onishi, Hiroyuki Taniguchi, Yu Matsuoka, Yoichiro Yanaka, Kenichi Izawa, Yu Tsuboi, Yasunori Mori, Shumpei Kono, Atsushi Nakayama, Kazuhiko Emoto, Noriaki
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Published in
Pulmonary Circulation
The existence of microvasculopathy in patients with chronic thromboembolic pulmonary hypertension has been suggested. Recently, dual-energy computed tomography has been used to produce a sensitive iodine distribution map in lung fields to indicate microvasculopathy according to poor subpleural perfusion. Our aim was to evaluate the impact of microv...
Chiba, Yasuyuki Iwano, Hiroyuki Kaga, Sanae Shinkawa, Mio Murayama, Michito Ohira, Hiroshi Ishizaka, Suguru Sarashina, Miwa Tsujinaga, Shingo Yokoyama, Shinobu
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Published in
Pulmonary Circulation
Evaluation of left ventricular filling pressure plays an important role in the clinical management of pulmonary hypertension. However, the accuracy of echocardiographic parameters for the determination of left ventricular filling pressure in the presence of pulmonary vascular lesions has not been fully addressed. We retrospectively investigated 124...
Fernandes, Caio J.C.S. da Silva, Taysa A.F. Alves Jr, Jose L. Jardim, Carlos V.P. de Souza, Rogerio
Published in
Pulmonary Circulation
Triple combination therapy is suggested in current pulmonary arterial hypertension guidelines in case of unsatisfactory treatment with oral double combination therapy. However, there is a lack of evidence concerning some of the drug combinations currently employed. We demonstrate the clinical and hemodynamical benefits of inhaled iloprost as third ...
