Published in Huisarts en wetenschap
Kennis over effectiviteit en implementatie van leefstijlinterventies voor patiënten met een hoog risico op hartvaatziekten in de eerste lijn is schaars. Daarom start er een onderzoek naar het effect en de implementatie-succesfactoren van een integrale groeps-leefstijlinterventie voor patiënten met een verhoogd risico op hartvaatziekten in de huisar...
Published in JGZ Tijdschrift voor jeugdgezondheidszorg
In januari 2017 is de jeugdgezondheidszorg (JGZ) Richtlijn Hartafwijkingen gepubliceerd. Deze richtlijn is een herziening van de in 2005 gepubliceerde JGZ-richtlijn Vroegtijdige opsporing van aangeboren hartafwijkingen. Een belangrijk doel van de herziene richtlijn is om JGZ-professionals te ondersteunen bij de vroegtijdige opsporing van (aangebore...
Cardiovascular diseases (CVD) are the main cause of death worldwide. Annually, about 17.5 million people die from CVD, accounting for ~30% of deaths worldwide. Elevated blood pressure (BP) is a major risk factor for CVD and the largest single contributor to global mortality. BP is a modifiable risk factor that is largely determined by lifestyle fac...
Lifestyle intervention studies have shown that the development of cardiometabolic diseases can be partly prevented or postponed by the combination of a healthy diet and physical activity. Cardiometabolic diseases and their risk factors are particularly prevalent among individuals with low socioeconomic status and some ethnic minorities, and therefo...
Epidemiological studies showed that the consumption of flavonoid-rich foods such as cocoa and tea is associated with a lower risk of cardiovascular disease (CVD). Randomised controlled trials (RCTs) showed that cocoa and tea improved markers of cardiometabolic health including blood pressure, endothelial function, insulin resistance, arterial stiff...
Cardiovascular diseases (CVD) are the main cause of death worldwide. In 2012, about 17.5 million people died from CVD, accounting for 30% of all deaths. High blood pressure (BP) is a major cardiovascular risk factor, which was responsible for 10.4 million deaths in 2013. Diet and lifestyle play an important role in the etiology of hypertension. Mai...
The health and economic burden related to cardiovascular diseases is substantial and prevention of these diseases remains a challenge. There is convincing evidence that high salt intake affects blood pressure and the risk of cardiovascular diseases. As salt intake is far above the recommended maximum level of intake, salt reduction may help to redu...
Thesis: Young Children and Obesity – Development and Evaluation of Family-oriented Treatment, Esther van Hoek Introduction The prevalence of childhood obesity has increased rapidly during the last decades. Childhood obesity is a multisystem disease with serious consequences such as hypertension, dyslipidemia, chronic inflammation, endothelial dysfu...
Summary Consumption of foods containing flavonoids is associated with a reduced risk of cardiovascular diseases (CVD), possibly by lipid-lowering effects. On the other hand, for one of these flavonoids, quercetin, also genotoxicity was shown especially in in vitro bioassays. Therefore, the first aim of this thesis was to identify mechanisms underly...
