A very uncommon haemoglobin value resulting from a severe acute malnutrition in a 16-month-old child in Ethiopia
Published in Clinical Chemistry and Laboratory Medicine (CCLM)
Management of Anaemia of Chronic Disease: Beyond Iron-Only Supplementation
Published in Nutrients
Chronic diseases are characterised by altered autophagy and protein metabolism disarrangement, resulting in sarcopenia, hypoalbuminemia and hypo-haemoglobinaemia. Hypo-haemoglobinaemia is linked to a worse prognosis independent of the target organ affected by the disease. Currently, the cornerstone of the therapy of anaemia is iron supplementation,...
Association of erythropoietin resistance and fibroblast growth factor 23 in dialysis patients: Results from the Japanese...
...Published in Nephrology (Carlton, Vic.)
Fibroblast growth factor 23 (FGF23) plays an important role in chronic kidney disease (CKD)-related mineral and bone disorders. High FGF23 levels are associated with increased risk of anaemia in non-haemodialysis CKD patients. FGF23 also negatively regulates erythropoiesis in mice. We hypothesized that higher FGF23 levels are associated with increa...
"Blass und müde" - Vorgehen bei V. a. Eisenmangel
Published in MMW - Fortschritte der Medizin
Non-invasive haemoglobin measurement as an index test to detect pre-operative anaemia in elective surgery patients - a p...
Published in Anaesthesia
Non-invasive haemoglobin measurement using absolute values lacks the precision to be the sole basis for the treatment of pre-operative anaemia. However, it can possibly serve as a screening test, indexing 'anaemia' with high sensitivity when values remain under prespecified cut-off values. Based on previous data, non-invasive haemoglobin cut-off va...
Prevalence, associated factors and cardiocerebral vascular prognosis of anaemia among patients on chronic haemodialysis ...
Published in The Journal of International Medical Research
Objective To assess the prevalence, associated factors and cardiocerebral vascular prognosis of anaemia in patients undergoing haemodialysis. Methods This multicentre, retrospective, observational cohort study included patients on maintenance haemodialysis in South Guangdong, China. Anaemia in haemodialysis was defined as haemoglobin (Hb)
Endurance of erythrocyte series in chemotherapy
Published in Experimental and Therapeutic Medicine
Hematopoietic bone marrow toxicity is most often the limiting factor for chemotherapy doses. Increasing the intensity of chemotherapy doses (higher doses or more frequent administration) would improve antitumor effects, but the hematological toxicity does not allow these dose increases. This study evaluated the impact of chemotherapies on the param...
Effect of red blood cell shape changes on haemoglobin interactions and dynamics: a neutron scattering study
Published in Royal Society Open Science
By using a combination of experimental neutron scattering techniques, it is possible to obtain a statistical perspective on red blood cell (RBC) shape in suspensions, and the inter-relationship with protein interactions and dynamics inside the confinement of the cell membrane. In this study, we examined the ultrastructure of RBC and protein–protein...
A left shift in the oxyhaemoglobin dissociation curve in patients with severe coronavirus disease 2019 (COVID‐19)
Published in British Journal of Haematology
Critically ill patients with coronavirus disease 2019 (COVID‐19) present with hypoxaemia and are mechanically ventilated to support gas exchange. We performed a retrospective, observational study of blood gas analyses ( n = 3518) obtained from patients with COVID‐19 to investigate changes in haemoglobin oxygen (Hb–O2) affinity. Calculated oxygen t...
Study of association of varicose veins and inflammation by inflammatory markers.
Published in Phlebology
In varicose veins, increased levels of inflammatory markers are indicators of endothelial damage and increased procoagulant activity. These findings support the assumption that the constitution of blood in varicose veins differs from that of systemic blood. The purpose of the study was a correlative study of blood constituents in varicose veins and...
