Liu, Jing Chen, Jiuliang Ye, Shuhong Ding, Yan Guo, Shuhang Fan, Ningning
Published in
Folia Horticulturae
Ginkgolic acid is a natural plant antifungal substance with important biological activities, present in the testa of Ginkgo biloba. This research aims to analyse the antifungal action of ginkgolic acid against pathogenic fungi. Ginkgolic acid was analyzed by HPLC and FTIR, and the in vitro inhibitory activities of ginkgolic acid against pathogenic ...
Kyei-Baafour, Eric Kusi, Kwadwo Asamoah Arthur, Fareed K.N. Tiendrebeogo, Regis W. Owusu-Yeboa, Eunice Singh, Susheel K. Friedrich, Sarah Gerds, Thomas A. Dodoo, Daniel Theisen, Michael
...
Published in
Frontiers in Immunology
Background Naturally acquired immunity to malaria may involve different immune mechanisms working in concert, however, their respective contributions and potential antigenic targets have not been clearly established. Here, we assessed the roles of opsonic phagocytosis and antibody-mediated merozoite growth inhibition in Plasmodium falciparum (P. fa...
Chandrasekaran, Balaji Tyagi, Ashish Saran, Uttara Kolluru, Venkatesh Baby, Becca V. Chirasani, Venkat R. Dokholyan, Nikolay V. Lin, Jyh M. Singh, Amandeep Sharma, Arun K.
...
Published in
Frontiers in Pharmacology
We investigated the efficacy of a small molecule ASR-600, an analog of Urolithin A (Uro A), on blocking androgen receptor (AR) and its splice variant AR-variant 7 (AR-V7) signaling in castration-resistant prostate cancer (CRPC). ASR-600 effectively suppressed the growth of AR+ CRPC cells by inhibiting AR and AR-V7 expressions; no effect was seen in...
Duperray, Maëlle François, Jean-Marie Capp, Jean-Pascal
The bacterial toxin–antitoxin systems are each composed of a toxin, which severely inhibits bacterial cells growth, and a specific neutralizing antitoxin. Some toxin–antitoxin systems are functional when expressed in the yeast Saccharomyces cerevisiae. For instance, the expression of the relE toxin gene leads to a strong growth defect in yeast, whe...
Stoica, Catalina Dinu, Laurentiu Razvan Lucaciu, Irina Eugenia Oncu, Voicu Gheorghe, Stefania Nita-Lazar, Mihai
Published in
International journal of environmental research and public health
Mine water as a result of meteoric and/or underground water's contact with tailings and underground workings could have an elevated content of metals associated with sulfate, often acidic, due to the bio-oxidation of sulfides. When entering aquatic ecosystems, the mine water can cause significant changes in the species' trophic levels, therefore a ...
Martins, Jean
This study examines the toxicity of the newly discovered molecule 6PPD-Quinone (6PPD-Q) to selected environmental microorganisms. After decades of intense research, this molecule, derived from a very common antioxidant (6PPD) used as a car tyre protector, has recently been identified as the main cause of the death of Coho salmon in the north-wester...
ciftci;, halilibrahim
Colorectal cancer (CRC) and breast cancer are leading causes of death globally, due to significant challenges in detection and management. The late-stage diagnosis and treatment failures require the discovery of potential anticancer agents to achieve a satisfactory therapeutic effect. We have previously reported a series of plastoquinone analogues ...
Fujii, Tadashi Tochio, Takumi Endo, Akihito
Published in
Journal of cosmetic dermatology
The close balance between Cutibacterium acnes and the skin flora, particularly between C. acnes phylotypes, has been suggested to play an important role in the onset of acne. C. acnes has been classified into ribotypes (RTs) based on polymorphisms in its 16S rRNA sequence, with RT4 and RT5 being associated with the onset of acne and RT6 with health...
ghorbel;, mouna
Catalase is a crucial enzyme in the antioxidant defense system protecting organisms from oxidative stress. Proteins of this kind play important roles in controlling plant response to biotic and abiotic stresses by catalyzing the decomposition of H2O2. The durum wheat catalase 1, TdCAT1, has been previously isolated and characterized. Here, using bi...
säle;, verena
Arbuscular mycorrhizal fungi (AMF) have multiple functions in agroecosystems and affect many processes below- and aboveground, including plant productivity. Mycorrhizal symbiosis is not necessarily beneficial for the host plant and the growth response can be not only positive but also neutral or negative. Among other factors, the responsiveness of ...
