Leinberger, Janina Holste, Jonas Bunk, Boyke Freese, Heike M. Spröer, Cathrin Dlugosch, Leon Kück, Anna-Carlotta Schulz, Stefan Brinkhoff, Thorsten
Published in
Frontiers in Microbiology
Secondary metabolites are key components in microbial ecology by mediating interactions between bacteria and their environment, neighboring species or host organisms. Bioactivities can be beneficial for both interaction partners or provide a competitive advantage only for the producer. Colonizers of confined habitats such as biofilms are known as p...
Hong, Weiyong Gao, Ying Lou, Bang Ying, Sanjun Wu, Wenchao Ji, Xugang Yu, Nan Jiao, Yunlong Wang, Haiying Zhou, Xuefeng
...
Published in
International Journal of Nanomedicine
Purpose To develop microchannel-based preparation of curcumin (Cur)-loaded hybrid nanoparticles using enzyme-targeted peptides and star-shaped polycyclic lipids as carriers, and to accomplish a desirable targeted drug delivery via these nanoparticles, which could improve the bioavailability and antitumor effects of Cur. Methods The amphiphilic tri-...
Gui, Yun Cheng, Jing Chen, Zhiguo
Published in
Experimental and Therapeutic Medicine
Oridonin, a compound from Rabdosia rubescens , has been shown to exhibit a potent ability to improve the antitumor effects of lentinan (LNT). In the present study, the effects of oridonin, LNT, and the combination of these treatments were assessed on the normal human fetal lung fibroblast cell line MRC-5, as well as the non-small cell lung cancer c...
Garcia, Marcelo Valle Garcia-Cela, Esther Magan, Naresh Copetti, Marina Venturini Medina, Angel
Published in
Frontiers in Microbiology
Bread and intermediate moisture bakery products are mainly spoiled by yeasts and filamentous fungi. The inoculum load and preservation system used determines their shelf life. To extend the shelf life of such commodities, the use of chemical preservatives is the most common way to try and control the initiation of mold spoilage of bread. This study...
Sarwar, Sadia Alamro, Abir A Alghamdi, Amani A Naeem, Komal Ullah, Salamat Arif, Muazzam Yu, Jun Qing Huq, Fazlul
Published in
Drug Design, Development and Therapy
Purpose Cisplatin resistance is a major concern in ovarian cancer treatment. The aim of this study was to investigate if wedelolactone could perform better in resistant ovarian cancer cells when used in combination with cisplatin. Methods Growth inhibitory potential of wedelolactone and cisplatin was investigated through MTT reduction assay in ovar...
Govc Pušnik, Dea
V magistrskem delu smo določali protiglivno aktivnost izvlečkov rastlinskih vrst Chamomilla recutita, Helichrysum arenarium, Humulus lupulus, Juniperus communis, Achillea millefolium, Calendula officinalis, Sambucus nigra, Nepeta cataria, Olea europaea, Hypericum perforatum, Taraxacum officinale, Crataegus sp., pripravljenih z ekstrakcijo s superkr...
Huang, Ke Zhao, Wei Wang, Xuqiao Qiu, Yingfei Liu, Zelin Chen, Rui Liu, Wei Liu, Bin
Published in
Frontiers in Oncology
Background Glioma has one of the highest mortality rates of all tumors of the nervous system and commonly used treatments almost always fail to achieve tumor control. Low-dose carbon-ion radiation can effectively target cancer and tumor cells, but the mechanisms of growth inhibition induced by heavy-ion radiation via the PI3K/Akt signaling pathway ...
Liu, Da Walcott, Ronald Mis Solval, Kevin Chen, Jinru
Published in
Foods
Interests in using biological agents for control of human pathogens on vegetable seeds are rising. This study evaluated whether probiotic bacterium Lactobacillus rhamnosus GG, bacterial strains previously used as biocontrol agents in plant science, as well as a selected plant pathogen could compete with foodborne human pathogens, such as Salmonella...
Ruiz, Stephanie J. van ’t Klooster, Joury S. Bianchi, Frans Poolman, Bert
Published in
Microorganisms
Amino acids are essential metabolites but can also be toxic when present at high levels intracellularly. Substrate-induced downregulation of amino acid transporters in Saccharomyces cerevisiae is thought to be a mechanism to avoid this toxicity. It has been shown that unregulated uptake by the general amino acid permease Gap1 causes cells to become...
Misiak, Marta Goodall-Copestake, William P Sparks, Tim H Worland, M Roger Boddy, Lynne Magan, Naresh Convey, Peter Hopkins, David W Newsham, Kevin K
Published in
Global change biology
Temperatures approaching or exceeding 20 °C have been measured during summer in polar regions at the surfaces of barren fellfield soils under cloudless skies around solar noon. However, despite the upper temperature limit for the growth of cold-adapted microbes - which are abundant in polar soils and have pivotal roles in nutrient cycling - typical...
