Gao, Ruyi Gu, Min Shi, Liwei Liu, Kaituo Li, Xiuli Wang, Xiaoquan Hu, Jiao Liu, Xiaowen Hu, Shunlin Chen, Sujuan
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Published in
Veterinary Research
Since 2014, clade 2.3.4.4 has become the dominant epidemic branch of the Asian lineage H5 subtype highly pathogenic avian influenza virus (HPAIV) in southern and eastern China, while the H5N6 subtype is the most prevalent. We have shown earlier that lack of glycosylation at position 158 of the hemagglutinin (HA) glycoprotein due to the T160A mutati...
Kościuszko, Artur Marciniak, Dawid Sykutera, Dariusz
Published in
Materials (Basel, Switzerland)
Dimensions of the injection-molded semi-crystalline materials (polymeric products) decrease with the time that elapses from their formation. The post-molding shrinkage is an effect of secondary crystallization; the increase in the degree of polymer crystallinity leads to an increase in stiffness and decrease in impact strength of the polymer materi...
Zhang, Jinming Peng, Qisheng Zhao, Weizheng Sun, Wanchun Yang, Jingbo Liu, Ning
Published in
Journal of proteome research
Influenza viruses continue evolving and have the ability to cause a global pandemic, so it is very important to elucidate its pathogenesis and find new treatment methods. In recent years, proteomics has made important contributions to describing the dynamic interaction between influenza viruses and their hosts, especially in posttranslational regul...
Abied, Adam Xu, Lei Sahlu, Bahlibi W Xing, Feng Ahbara, Abulgasim Pu, Yabin Lin, Jiang Berihulay, Haile Islam, Rabiul He, Xiaohong
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Published in
Genes
Homozygosity of long sequence genotypes are a result of parents transmitting identical haplotypes, which can be used to estimate their auto-zygosity. Therefore, we used high-density SNP Chip data to characterize the auto-zygosity of each breed according to the occurrence and distribution of runs of homozygosity (ROH). Subsequently, we identified th...
Islam, Rakibul Corraya, Rima Maria Pasovic, Lara Khan, Ayyad Zartasht Aass, Hans Christian D Eidet, Jon Roger Utheim, Tor Paaske
Published in
Molecules (Basel, Switzerland)
This study aimed to investigate how prolonged storage of adult retinal pigment epithelial (ARPE-19) cell sheets affects cell metabolism, morphology, viability, and phenotype. ARPE-19 cell sheets were stored at three temperatures (4 °C, 16 °C, and 37 °C) for three weeks. Metabolic status and morphology of the cells were monitored by sampling medium ...
Aw, R De Wachter, C Laukens, B De Rycke, R De Bruyne, M Bell, D Callewaert, N Polizzi, KM
The structural organization of the Golgi stacks in mammalian cells is intrinsically linked to function, including glycosylation, but the role of morphology is less clear in lower eukaryotes. Here we investigated the link between the structural organization of the Golgi and secretory pathway function using Pichia pastoris as a model system. To unsta...
Muñoz-Labrador, Ana Azcarate, Silvana Lebrón-Aguilar, Rosa Quintanilla-López, Jesús E Galindo-Iranzo, Plácido Kolida, Sofia Methven, Lisa Rastall, Robert A Moreno, F Javier Hernandez-Hernandez, Oswaldo
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Published in
Foods (Basel, Switzerland)
To improve flavor profiles, three cyclodextrin glucosyltransferases (CGTases) from different bacteriological sources, Paenibacillus macerans, Geobacillus sp. and Thermoanaerobacter sp., were used with an extract of steviol glycosides (SVglys) and rebaudioside A (RebA) as acceptor substrates in two parallel sets of reactions. A central composite exp...
Bandini, Giulia Agop-Nersesian, Carolina van der Wel, Hanke Mandalasi, Msano Kim, Hyun W West, Christopher M Samuelson, John
Published in
The Journal of biological chemistry
Once considered unusual, nucleocytoplasmic glycosylation is now recognized as a conserved feature of eukaryotes. While in animals, O-GlcNAc transferase (OGT) modifies thousands of intracellular proteins, the human pathogen Toxoplasma gondii transfers a different sugar, fucose, to proteins involved in transcription, mRNA processing, and signaling. K...
Kadirvelraj, Renuka Yang, Jeong-Yeh Kim, Hyun Woo Sanders, Justin H Moremen, Kelley W Wood, Zachary A
Published in
The Journal of biological chemistry
Poly-N-acetyl-lactosamine (poly-LacNAc) structures are composed of repeating [-Galβ(1,4)-GlcNAcβ(1,3)-]n glycan extensions. They are found on both N- and O--glycoproteins and glycolipids, and play an important role in development, immune function, and human disease. The majority of mammalian poly-LacNAc is synthesized by the alternating iterative a...
Lee, Jua Ha, Seungshin Kim, Minsoo Kim, Seong-Wook Yun, Jaekyung Ozcan, Sureyya Hwang, Heeyoun Ji, In Jung Yin, Dongtan Webster, Maree J
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Published in
Proceedings of the National Academy of Sciences of the United States of America
Mammalian brain glycome remains a relatively poorly understood area compared to other large-scale "omics" studies, such as genomics and transcriptomics due to the inherent complexity and heterogeneity of glycan structure and properties. Here, we first performed spatial and temporal analysis of glycome expression patterns in the mammalian brain usin...
