choi, jong-chul kim, min-sik choi, hwi-yeon kang, yeong-lim choi, in-yeong jung, sung-won jeong, ji-yun kim, min-chul cho, andrew y. lee, ji-ho
...
N-linked glycans covering GP5 neutralizing epitopes of porcine reproductive and respiratory syndrome virus (PRRSV) have been proposed to act as a sheath blocking the production of neutralizing antibodies. Herein, we genetically engineered PRRSV with serine (S) substitution on the 44th asparagine (N) on the GP5 ectodomain of PRRSV-2 lineage-1. To ev...
Zhang, Yong Zeng, Wenjuan Zhao, Yang Yang, Hao
Published in
Frontiers in Molecular Biosciences
McDowell, Colin T Lu, Xiaowei Mehta, Anand S Angel, Peggi M Drake, Richard R
Published in
Mass spectrometry reviews
Glycosylation is an important posttranslational modifier of proteins and lipid conjugates critical for the stability and function of these macromolecules. Particularly important are N-linked glycans attached to asparagine residues in proteins. N-glycans have well-defined roles in protein folding, cellular trafficking and signal transduction, and al...
tyrrell, beatrice e. kumar, abhinav gangadharan, bevin alonzi, dominic brun, juliane hill, michelle bharucha, tehmina bosworth, andrew graham, victoria dowall, stuart
...
Crimean-Congo haemorrhagic fever virus (CCHFV) is a pathogen of increasing public health concern, being a widely distributed arbovirus and the causative agent of the potentially fatal Crimean-Congo haemorrhagic fever. Hazara virus (HAZV) is a genetically and serologically related virus that has been proposed as a surrogate for antiviral and vaccine...
Oh, Myung Jin Lee, Sung Hyeon Kim, Unyoung An, Hyun Joo
Published in
Mass spectrometry reviews
Serum haptoglobin (Hp), a highly sialylated biomolecule with four N-glycosylation sites, is a positive acute-phase response glycoprotein that acts as an immunomodulator. Hp has gained considerable attention due to its potential as a signature molecule that exhibits aberrant glycosylation in inflammatory disorders and malignancies. Its glycosylation...
Grandits, Melanie Grünwald-Gruber, Clemens Gastine, Silke Standing, Joseph F. Reljic, Rajko Teh, Audrey Y-H. Ma, Julian K-C.
Published in
Frontiers in Plant Science
Introduction Broadly neutralising antibodies are promising candidates for preventing and treating Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS), as an alternative to or in combination with antiretroviral therapy (ART). These mAbs bind to sites on the virus essential for virus attachment and entry, thereby inhibiting ent...
tan, li jianfeng, xu held, michael a. lamport, derek t. kieliszewski, marcia
Arabinogalactan-proteins (AGPs) are members of the hydroxyproline-rich glycoprotein (HRGP) superfamily. They are heavily glycosylated with arabinogalactans, which are usually composed of a β-1,3-linked galactan backbone with 6-O-linked galactosyl, oligo-1,6-galactosyl, or 1,6-galactan side chains that are further decorated with arabinosyl, glucuron...
shan, jing da-jin, li wang, xiao-qiu
Endometriosis is the most common cause of infertility. Endometrial receptivity has been suggested to contribute to infertility and poor reproductive outcomes in affected women. Even though experimental and clinical data suggest that the endometrium differs in women with endometriosis, the pathogenesis of impaired endometrial receptivity remains inc...
morell, pere lópez-garcía, adrián hernando, isabel quiles, amparo
Pea protein has been extensively studied because of its high nutritional value, low allergenicity, environmental sustainability, and low cost. However, the use of pea protein in some food products is hindered due to the low functionality of pea protein, especially as an emulsifier. High-internal-phase emulsions (HIPEs) are attracting attention beca...
radovani, barbara vučković, frano maggioni, aldo p. ferrannini, ele lauc, gordan gudelj, ivan
Coronary artery disease (CAD) is the most common cardiovascular disease (CVD), and previous studies have shown a significant association between N-glycosylation, a highly regulated posttranslational modification, and the development of atherosclerotic plaques. Our aim was to determine whether the N-glycome of immunoglobulin G (IgG) is associated wi...
