Luo, Guotian Wosinski, Pauline Salazar-Noratto, Giuliana E Bensidhoum, Morad Bizios, Rena Marashi, Sayed-Amir Potier, Esther Sheng, Puyi Petite, Hervé
Published in
Tissue engineering. Part B, Reviews
Mesenchymal stromal cells (MSCs) are considered promising candidates for regenerative medicine applications. Their clinical performance postimplantation, however, has been disappointing. This lack of therapeutic efficacy is most likely due to suboptimal formulations of MSC-containing material constructs. Tissue engineers, therefore, have developed ...
Xiong, Xinglong Chen, Dongxu Cai, Shuang Qiu, Li Shi, Jing
Published in
Frontiers in Cardiovascular Medicine
Background The association between intraoperative hyperglycemia (IH) and postoperative infections in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) is inadequately studied. Methods A total of 3,428 patients who underwent cardiac surgery with CPB at our institution between June 1, 2019 and July 30, 2021 were enrolled to evalua...
Rodrigues, Joana Saraiva Faria-Pereira, Andreia Camões, Sérgio Póvoas Serras, Ana Sofia Morais, Vanessa Alexandra Ruas, Jorge Lira Miranda, Joana Paiva
Published in
Frontiers in Endocrinology
Introduction The development of reliable hepatic in vitro models may provide insights into disease mechanisms, linking hepatocyte dysmetabolism and related pathologies. However, several of the existing models depend on using high concentrations of hepatocyte differentiation-promoting compounds, namely glucose, insulin, and dexamethasone, which is a...
Xu, Yue Huo, Liyue Zhao, Keke Li, Yawei Zhao, Xinran Wang, Huiying Wang, Wenli Shi, Haiyan
Published in
Frontiers in Plant Science
Salicylic acid (SA) and ethylene (ET) are crucial fruit senescence hormones. SA inhibited ET biosynthesis. However, the mechanism of SA delaying fruit senescence is less known. ETHYLENE INSENSITIVE 3 (EIN3), a key positive switch in ET perception, functions as a transcriptional activator and binds to the primary ET response element that is present ...
Dong, Gaoquan Fan, Mengwei Wang, Hainan Leng, Yadong Sun, Junting Huang, Jun Zhang, Hao Yan, Jie
Published in
Plants (Basel, Switzerland)
Taraxacum kok-saghyz is a model species for studying natural rubber biosynthesis because its root can produce high-quality rubber. Small rubber particle protein (SRPP), a stress-related gene to multiple stress responses, involves in natural rubber biosynthesis. To investigate the transcriptional regulation of the TkSRPP promoter, the full-length pr...
Corbee, Ronald J. van Everdingen, Dion L. Kooistra, Hans S. Penning, Louis C.
Published in
Frontiers in Veterinary Science
Fibroblast growth factors (FGFs) are involved in numerous metabolic processes. The endocrine subfamily of FGFs, consisting of FGF19, FGF21, and FGF23, might have beneficial effects in the treatment of diabetes mellitus (DM) and/or obesity. The analog with the greatest potential, FGF21, lowers blood glucose levels, improves insulin sensitivity, and ...
Lin, Shan Lai, Dingfeng He, Wanmei
Published in
Frontiers in Endocrinology
Background Hyperglycemia is one of the poor prognostic factors in critical ill sepsis patients with diabetes. We aimed to assess the interaction between admission glucose level and clinical endpoints in sepsis patients with diabetes admitted in the intensive care unit (ICU). Methods Data from the Medical Information Mart Intensive Care III database...
Wieser, Manuela Beckmann, Katrin Melanie Kutter, Annette P. N. Mauri, Nico Richter, Henning Zölch, Niklaus Bektas, Rima Nadine
Published in
Frontiers in Veterinary Science
Introduction In recent years ketamine has increasingly become the focus of multimodal emergency management for epileptic seizures. However, little is known about the effect of ketamine on brain metabolites in epileptic patients. Magnetic resonance spectroscopy (MRS) is a non-invasive technique to estimate brain metabolites in vivo. Our aim was to m...
Pixner, Thomas Stummer, Nathalie Schneider, Anna Maria Lukas, Andreas Gramlinger, Karin Julian, Valérie Thivel, David Mörwald, Katharina Mangge, Harald Dalus, Christopher
...
Published in
Frontiers in Endocrinology
Until recently, glucagon was considered a mere antagonist to insulin, protecting the body from hypoglycemia. This notion changed with the discovery of the liver-alpha cell axis (LACA) as a feedback loop. The LACA describes how glucagon secretion and pancreatic alpha cell proliferation are stimulated by circulating amino acids. Glucagon in turn lead...
Guijarro-Real, Carla Adalid-Martínez, Ana M Pires, Cherrine K Ribes-Moya, Ana M Fita, Ana Rodríguez-Burruezo, Adrián
Published in
Plants (Basel, Switzerland)
Peppers (Capsicum sp.) are used both as vegetables and/or spice and their fruits are used in a plethora of recipes, contributing to their flavor and aroma. Among flavor-related traits, pungency (capsaicinoids) and lately volatiles have been considered the most important factors. However, the knowledge of sugars is low, probably due to the fact pepp...
