Săftescu, Sorin Popovici, Dorel Oprean, Cristina Negru, Alina Haiduc, Anita Stanca, Simona Malița, Daniel-Claudiu Volovăț, Simona Negru, Șerban
Published in
Experimental and therapeutic medicine
Cisplatin remains one of the most active antineoplastic treatments used in oncology, being the most prestigious exponent of the golden age in chemotherapy at the end of the 20th century. This chemotherapeutic drug is used for curative or palliative treatments in testicular, ovarian, head and neck neoplasms, sarcomas and lymphomas. The limiting dose...
Lowe, Marcus Payton, Antony Verma, Arpana Gemmell, Isla Worthington, Judith Hamilton, Patrick Ollier, William Augustine, Titus Poulton, Kay
Published in
HLA
Human leukocyte antigens (HLA) have been associated with renal function, but previous studies report contradictory findings. There has been a lack of research into how HLA affects renal function in Black, Asian and Minority Ethnic (BAME) people in the UK, despite BAME people being disproportionately affected by renal dysfunction. This study include...
Seegmiller, Jesse C Eckfeldt, John H
Published in
Clinical chemistry
Tommerdahl, Kalie L Bjornstad, Petter Kendrick, Jessica Cree-Green, Melanie Baumgartner, Amy D Pyle, Laura Reusch, Jane E B Nadeau, Kristen J
Published in
Diabetes, obesity & metabolism
Youth with type 1 diabetes (T1D) demonstrate insulin resistance, independently of glycaemia, when compared to normoglycaemic peers. Insulin resistance increases the risk of cardiovascular disease and diabetic kidney disease, factors also associated with systemic inflammation. We evaluated the effect of metformin on markers of inflammation and diabe...
Collard, Didier van de Velde, Lennart Vogt, Liffert van den Born, Bert-Jan H
Published in
Journal of the American Society of Nephrology : JASN
Björk, Jonas; Nyman, Ulf; Larsson, Anders; Delanaye, Pierre; Pottel, Hans; 3149;
The CKD-EPI creatinine-based estimation equation for glomerular filtration rate (GFR) cannot be used in children, overestimates GFR in young adults, and its combination with the KDIGO recommended pediatric CKiD (Schwartz bedside) equation causes implausible increases in estimated GFR when switching from pediatric to adult care. By establishing sex-...
Friedman, Allon N Considine, Robert V Quinney, Sara K
Published in
Renal failure
Bariatric surgery is known to attenuate glomerular hyperfiltration over the long term and thereby protect the kidney from mechanical damage. Whether this effect is directly related to weight loss or is independent of weight as are some of its other beneficial metabolic effects is not known. We explored this question in a preliminary study that dire...
Kuźma, Łukasz Małyszko, Jolanta Kurasz, Anna Niwińska, Marta Maria Zalewska-Adamiec, Małgorzata Bachórzewska-Gajewska, Hanna Dobrzycki, Sławomir
Published in
Renal failure
Coexistence of chronic kidney disease (CKD) in the case of acute coronary syndromes (ACS) significantly worsens the outcomes. The aim of our study was to assess renal function impact on mortality among patients with ACS. The study was based on records of 21,985 patients hospitalized in the Medical University of Bialystok in 2009-2015. Inclusion cri...
Zhang, Wei Yi, Hui-ming Zhang, Xiao-le Yi, Yong-hong Zhou, Jian-hua Qiu, Li-ru
Published in
Current Medical Science
Vesicoureteral reflux (VUR) is one of the most common urinary tract anomalies in children and causes renal damage and studies focusing on the effect of VUR on renal function are rare. We recruited 35 primary VUR patients with recurrent urinary tract infection (UTI) and 10 non-VUR patients with recurrent UTI. Contrast-enhanced voiding urosonography ...
Kritmetapak, Kittrawee Charoensri, Suranut Thaopanya, Rattrai Pongchaiyakul, Chatlert
Published in
International Journal of General Medicine
Purpose The long-term impact of changes in serum uric acid (SUA) concentration on the estimated glomerular filtration rate (eGFR) among the general population remains unclear. We investigated the longitudinal associations between changes in SUA and eGFR over 10 years in 1222 participants with baseline eGFR ≥60 mL/min/1.73 m2. Methods This was a 10-...