Holkar, Somnath Kadappa Balasubramaniam, Parameswari Kumar, Atul Kadirvel, Nithya Shingote, Prashant Raghunath Chhabra, Manohar Lal Kumar, Shubham Kumar, Praveen Viswanathan, Rasappa Jain, Rakesh Kumar
...
Published in
The Plant Pathology Journal
Sugarcane yellow leaf virus (SCYLV) is a distinct member of the Polerovirus genus of the Luteoviridae family. SCYLV is the major limitation to sugarcane production worldwide and presently occurring in most of the sugarcane growing countries. SCYLV having high genetic diversity within the species and presently ten genotypes are known to occur based ...
Gatticchi, Leonardo de las Heras, Jose I. Sivakumar, Aishwarya Zuleger, Nikolaj Roberti, Rita Schirmer, Eric C.
Published in
Frontiers in Cell and Developmental Biology
Tissue-specific patterns of radial genome organization contribute to genome regulation and can be established by nuclear envelope proteins. Studies in this area often use cancer cell lines, and it is unclear how well such systems recapitulate genome organization of primary cells or animal tissues; so, we sought to investigate radial genome organiza...
van Schaik, Tom Vos, Mabel Peric-Hupkes, Daan Hn Celie, Patrick van Steensel, Bas
Published in
EMBO reports
In mammalian interphase nuclei, more than one thousand large genomic regions are positioned at the nuclear lamina (NL). These lamina-associated domains (LADs) are involved in gene regulation and may provide a backbone for the folding of interphase chromosomes. Little is known about the dynamics of LADs during interphase, in particular at the onset ...
DasGupta, Abhimanyu Lee, Tammy L. Li, Chengyin Saltzman, Arneet L.
Published in
Frontiers in Cell and Developmental Biology
In most eukaryotes, the genome is packaged with histones and other proteins to form chromatin. One of the major mechanisms for chromatin regulation is through post-translational modification of histone proteins. Recognition of these modifications by effector proteins, often dubbed histone “readers,” provides a link between the chromatin landscape a...
Gupta, Shivani Santoro, Raffaella
Published in
Stem Cell Reports
In this review article, Santoro and colleague describe the regulation and role of the largest subnuclear compartment of the cell, the nucleolus, in embryonic stem cells (ESCs). Specifically, the authors highlight recent findings describing how the hyperactive transcriptional state and open chromatin structure of ribosomal RNA genes, which are locat...
Penagos-Puig, Andrés Furlan-Magaril, Mayra
Published in
Frontiers in Cell and Developmental Biology
Heterochromatin is a constituent of eukaryotic genomes with functions spanning from gene expression silencing to constraining DNA replication and repair. Inside the nucleus, heterochromatin segregates spatially from euchromatin and is localized preferentially toward the nuclear periphery and surrounding the nucleolus. Despite being an abundant nucl...
Qiu, Yi Huang, Suming
Published in
Leukemia
Recent technological advancements and genome-wide studies provide compelling evidence that dynamic chromatin interaction and three-dimensional genome organization in nuclei play an important role in regulating gene expression. Mammalian genomes consist of many small functional domains termed topologically associated domains (TADs), many of them org...
Woodruff, Gavin C Teterina, Anastasia A
Published in
Molecular biology and evolution
The abundance, diversity, and genomic distribution of repetitive elements is highly variable among species. These patterns are thought to be driven in part by reproductive mode and the interaction of selection and recombination, and recombination rates typically vary by chromosomal position. In the nematode Caenorhabditis elegans, repetitive elemen...
Ge, Zhongming Carrasco, Sebastian E. Feng, Yan Bakthavatchalu, Vasudevan Annamalai, Damodaran Kramer, Robin Muthupalani, Sureshkumar Fox, James G.
Published in
Emerging Microbes & Infections
Inclusion body nephropathy (IBN) and kidney fibrosis in aged immunodeficient mice and, to lesser extent, in immunocompetent mice have been recently linked to infection of mouse kidney parvovirus (MKPV), also known as murine chapparvovirus (MuCPV). Knowledge about its prevalence and the complete genome sequence of more MKPV strains is essential for ...
Khelifi, Gabriel Hussein, Samer M I
Published in
Frontiers in cell and developmental biology
