Miyamoto, Shunsuke Nakayama, Meijin Kano, Koichi Tsutsumi, Shohei Momiyama, Kaho Matsuki, Takashi Yamashita, Taku
Published in
Asia-Pacific journal of clinical oncology
Fluorescence imaging (FI) using indocyanine green (ICG) is a noteworthy alternative technique for sentinel lymph node (SLN) detection without radiation exposure in oral cavity and oropharynx cancer. However, conventional FI is monochrome, so the visibility is limited. This study assessed whether color FI using the HyperEye Medical System (HEMS) is ...
Serena, Thomas E. Snyder, Robert J. Bowler, Philip G.
Published in
Frontiers in Cellular and Infection Microbiology
Introduction Wound microflora in hard-to-heal wounds is invariably complex and diverse. Determining the interfering organisms(s) is therefore challenging. Tissue sampling, particularly in large wounds, is subjective and, when performed, might involve swabbing or biopsy of several locations. Fluorescence (FL) imaging of bacterial loads is a rapid, n...
Gao, Duyang Li, Yaxi Wu, Yayun Liu, Yu Hu, Dehong Liang, Simin Liao, Jiuling Pan, Min Zhang, Pengfei Li, Kai
...
Published in
ACS applied materials & interfaces
The application of an exogenous polymer matrix to construct aggregation-induced emission (AIE) nanoprobes promotes the utility of AIE luminogens (AIEgens) in diagnosing brain diseases. However, the limited fluorescence (FL) and low active-targeting abilities of AIE-based nanoprobes impede their imaging application. Here, we employed endogenous albu...
Yashin, Konstantin Novikova, Tatiana Shcheslavskiy, Vladislav
Published in
Frontiers in Oncology
kong, xiangyi gao, nan jianshi, du zhao, qing
The complications of inflammatory bowel diseases (IBDs) seriously endanger people’s health, such as bleeding, polyp hyperplasia, and even cancer. Although the precise pathophysiology of IBD is unknown, alterations in the intestinal lymphatic network, such as lymphangiogenesis and lymphatic vessel dysfunction, are well-established features. Therefor...
pavlova, marina a. panchenko, pavel a. alekhina, ekaterina a. ignatova, anastasia a. plyutinskaya, anna d. pankratov, andrey a. pritmov, dmitriy a. grin, mikhail a. feofanov, alexey v. fedorova, olga a.
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Herein, we report a new conjugate BChl–S–S–NI based on the second-generation photosensitizer bacteriochlorin e6 (BChl) and a 4-styrylnaphthalimide fluorophore (NI), which is cleaved into individual functional fragments in the intracellular medium. The chromophores in the conjugate were cross-linked by click chemistry via a bis(azidoethyl)disulfide ...
Liu, Ying Hu, Kaibo Lian, Guangchang Zhou, Meng Lu, Chichong Jin, Guofan
Published in
Chemistry & biodiversity
Curcumin has a wide range of pharmacological activities, which can be used to treat tumors, inflammation and other diseases. However, curcumin's poor solubility and low bioavailability limit its application. In this article, the structure of curcumin was modified with boron trifluoride ether to change fluorescent labeling. The compounds were then e...
Tian, Zuhong Liang, Shuhui Zhou, Xinmin Luo, Hui Tian, Miaomiao Zhang, Xianghan Guo, Changcun Zhang, Jing
Published in
Frontiers in Oncology
Introduction Positive resection margins occur in about 2.8%-8.2% gastric cancer surgeries and is associated with poor prognosis. Intraoperative guidance using Nearinfrared (NIR) fluorescence imaging is a promising technique for tumor detection and margin assessment. The goal of this study was to develop a tumor-specific probe for real-time intraope...
Morgan, Jessica M. Jelenska, Joanna Hensley, Dale Retterer, Scott T. Morrell-Falvey, Jennifer L. Standaert, Robert F. Greenberg, Jean T.
Published in
Frontiers in Plant Science
Transient transformation in plants is a useful process for evaluating gene function. However, there is a scarcity of minimally perturbing methods for gene delivery that can be used on multiple organs, plant species, and non-excised tissues. We pioneered and demonstrated the use of vertically aligned carbon nanofiber (VACNF) arrays to efficiently pe...
subach, oksana m. vlaskina, anna v. agapova, yuliya k. korzhenevskiy, dmitriy a. nikolaeva, alena y. varizhuk, anna m. subach, maksim f. patrushev, maxim v. piatkevich, kiryl d. boyko, konstantin m.
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NTnC-like green fluorescent genetically encoded calcium indicators (GECIs) with two calcium ion binding sites were constructed using the insertion of truncated troponin C (TnC) from Opsanus tau into green fluorescent proteins (GFPs). These GECIs are small proteins containing the N- and C-termini of GFP; they exert a limited effect on the cellular f...