Wiseman, James A Dragunow, Mike I-H Park, Thomas
Published in
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
Identifying and interrogating cell type-specific populations within the heterogeneous milieu of the human brain is paramount to resolving the processes of normal brain homeostasis and the pathogenesis of neurological disorders. While brain cell type-specific markers are well established, most are localized on cellular membranes or within the cytopl...
Beatriz Álvarez Flores, Maria Sopeña Corvinos, María Medrano Élez, María Soto Del Pecho, Beatriz Conejo Sánchez, Luz García de la Fe, Javier Guillén Santos, Raquel Cava Valenciano, Fernado
Published in
Pathology
Hodgkin lymphoma (HL) appears to originate from germinal centre B cells but lacks expression of most B cell markers. In contrast to non-Hodgkin B lymphomas, HL is not routinely diagnosed using flow cytometry techniques, and diagnosis is mainly based on immunohistochemical and cytomorphological pathology studies. Hodgkin and Reed-Sternberg cells are...
Sharma, Sunita Gaur, Kavita Perme, Tatton Singh, Amrita
Published in
Fetal and pediatric pathology
Background: B-cell acute lymphoblastic leukemia is known for heterogeneous blast morphology. Cytoplasmic granules and blebs have both been described, but not together, in lymphoblasts. Case presentation: A 7-year-old boy presented with fever, abdominal distension for 3 weeks, with hepatosplenomegaly. Investigations revealed pancytopenia, peripheral...
Montanari, Chiara Barbieri, Federica Lorenzini, Silvia Gottardi, Davide Šimat, Vida Özogul, Fatih Gardini, Fausto Tabanelli, Giulia
Published in
Frontiers in Nutrition
Introduction Enterococci are lactic acid bacteria (LAB) usually found as food contaminants in fermented products such as cheeses and fermented sausages. Due to their antibiotic resistance, the presence of virulence factors, and the ability to produce biogenic amines (BAs), the determination of these bacteria is crucial to assure food quality and sa...
Hillman, Hannah Khan, Nabeela Singhania, Akul Dubelko, Paige Soldevila, Ferran Tippalagama, Rashmi DeSilva, Aruna D. Gunasena, Bandu Perera, Judy Scriba, Thomas J.
...
Published in
Frontiers in Immunology
Introduction Previous studies suggest that monocytes are an important contributor to tuberculosis (TB)-specific immune signatures in blood. Methods Here, we carried out comprehensive single-cell profiling of monocytes in paired blood samples of active TB (ATB) patients at diagnosis and mid-treatment, and healthy controls. Results At diagnosis, ATB ...
Roy, Garbiñe Fernández-Bañares, Fernando Corzo, María Gómez-Aguililla, Sara García-Hoz, Carlota Núñez, Concepción
Published in
Frontiers in Immunology
Accurate celiac disease (CD) diagnosis is still challenging for some specific patients or circumstances. Thus, much effort has been expended last decades focused on seronegative or low grade enteropathy CD and, especially, on enable early diagnosis of individuals on a gluten-free diet (GFD). We discuss here two diagnostic approaches based on immuno...
Súkeníková, Lenka Černý, Viktor Thon, Tomáš Roubalová, Radka Jirásková Zákostelská, Zuzana Novotná, Olga Petrásková, Petra Boráková, Kristýna Kocourková, Ingrid Lodinová-Žádníková, Rája
...
Published in
Frontiers in Immunology
Introduction Probiotic administration seems to be a rational approach to promote maturation of the neonatal immune system. Mutual interaction of the microbiota with the host immune system is critical for the setting of appropriate immune responses including a tolerogenic one and thevmaintenance of homeostasis. On the other hand, our knowledge on th...
Pernice, Massimo C. Gasol, Josep M.
Published in
Frontiers in Microbiology
On a standard oceanographic cruise, flow cytometry data are usually collected sparsely through a bottle-based sampling and with stations separated by kilometers leading to a fragmented view of the ecosystem; to improve the resolution of the datasets produced by this technique here it is proposed the application of an automatic method of sampling an...
Midani, Firas S. David, Lawrence A.
Published in
Frontiers in Microbiology
Cross feeding between microbes is ubiquitous, but its impact on the diversity and productivity of microbial communities is incompletely understood. A reductionist approach using simple microbial communities has the potential to detect cross feeding interactions and their impact on ecosystem properties. However, quantifying abundance of more than tw...
Munteanu, Camelia Berindean, Ioana Mihai, Mihaela Pop, Bianca Popa, Mihai Muntean, Leon Petrescu, Olivia Ona, Andreea
Published in
Frontiers in Medicine
It has been proven that vitamins play an essential role in preventing certain diseases since ancient times. It is thus fruitless to approach the roles of vitamins without making reference to the techniques used in evaluating the effects of these micronutrients. Therefore, the aim of this paper was to summarize the immunological effects of E, K, B5,...
