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Factor H-related protein 1 (FHR-1): A complement regulatory protein and guardian of necrotic type surfaces.

Skerka, Christine Pradel, Gabriele Halder, Luke D Zipfel, Peter F Zipfel, Svante L H Strauß, Olaf

Published in British journal of pharmacology

Factor H-related protein 1 (FHR-1) is a member of the factor H protein family, which is involved in regulating innate immune complement reactions. Genetic modification of the encoding gene, CFHR1 on human chromosome 1, is involved in diseases such as age-related macular degeneration, C3-glomerulopathy, and atypical hemolytic uremic syndrome, indica...

Lyme Disease

Norris, S.J.

Published in Encyclopedia of Microbiology

Lyme disease (also called Lyme borreliosis) is a tick-transmitted infection caused by a group of closely related spirochetes of the genus Borrelia. It is most common in areas with a high prevalence of infected Ixodes ticks, a reservoir of transmission-competent small animals (including rodents and/or birds), and the presence of deer or other large ...

Publication search with factor H-related protein 1 as keyword

Factor H-related protein 1 (FHR-1): A complement regulatory protein and guardian of necrotic type surfaces.

Lyme Disease

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