Lin, Yonghua Zhang, Baoyan Su, Linfeng Wei, Jianfeng Chen, Zhichao Wu, Min
Published in
Biotechnology & genetic engineering reviews
Hepatic carcinoma (HCC) is one of the most common malignant tumors worldwide, and the prognosis of HCC patients is often poor. Long-chain non-coding RNA (lncRNA) distal-less homeobox 6 antisense 1 (DLX6-AS1) has been shown to be involved in the pathogenesis of various cancers. This study aims to investigate the expression of DLX6-AS1 in HCC patient...
touramanidou, loukia gurung, sonam cozmescu, claudiu a. perocheau, dany moulding, dale finn, patrick f. frassetto, andrea waddington, simon n. gissen, paul baruteau, julien
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Recently approved adeno-associated viral (AAV) vectors for liver monogenic diseases haemophilia A and B are exemplifying the success of liver-directed viral gene therapy. In parallel, additional gene therapy strategies are rapidly emerging to overcome some inherent AAV limitations, such as the non-persistence of the episomal transgene in the rapidl...
oeller, michaela schally, tanja zimmermann, georg lauth, wanda schallmoser, katharina rohde, eva laner-plamberger, sandra
In regenerative medicine, stromal cells are supposed to play an important role by modulating immune responses and differentiating into various tissue types. The aim of this study was to investigate the influence of heparin, frequently used as an anticoagulant in human platelet lysate (HPL)-supplemented cell cultures, on the expression of non-coding...
kozłowski, mateusz borzyszkowska, dominika golara, anna durys, damian piotrowska, katarzyna kempińska-podhorodecka, agnieszka cymbaluk-płoska, aneta
Background: Ovarian cancer is one of the most common cancers in women. Markers associated with ovarian cancer are still being sought. The aim of this study was to evaluate the expression of BRIP-1 (FANCJ) and FANCI proteins in ovarian cancer tissue and to assess these expressions in differentiating the described clinical features. Methods: The stud...
cui, hong-hui sun, man-man huang, xiao-juan liao, hong-ze
Methyl-CpG-binding domain (MBD) proteins play vital roles in epigenetic gene regulation, and they have diverse molecular, cellular, and biological functions in plants. MBD proteins have been functionally characterized in a few plant species. However, the structure and function of MBD proteins in Arabidopsis halleri and Arabidopsis lyrata remain unk...
Zhang, Wenqian Fu, Jiewen Du, Jiaman Liu, Xiaoyan Cheng, Jingliang Wei, Chunli Xu, Youhua Fu, Junjiang
Published in
Frontiers in Immunology
tan, fang ren, lixuan kong, chang-suk
This study aimed to observe the therapeutic effect of Lactiplantibacillus plantarun HFY11 (LP-HFY11) on lincomycin hydrochloride-induced diarrhea in mice. The results showed that LP-HFY11 alleviated weight loss and intestinal and colon tissue lesions caused by diarrhea. The serum assay showed that LP-HFY11 decreased interleukin 17A (IL-17A), IL-6, ...
De Lima, Erika Urbano Dos Santos, Filipe Ferreira Da Silva, Igor Campos De Lima, Cláudio Rogério Alves Frutuoso, Vitoria Sousa Caso, Gustavo Felisola De Oliveira, Paloma Ramos Bezerra, Ana Karina Cerutti, Janete Maria Tamura, Rodrigo Esaki
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Published in
Frontiers in Endocrinology
Introduction Forkhead box E1 (FOXE1) is a transcription factor with a crucial role in thyroid morphogenesis and differentiation. Promoter hypermethylation downregulates FOXE1 expression in different tumor types; nevertheless, its expression and relationship with methylation status in differentiated thyroid cancer (DTC) remain unclear. Methods A tot...
Han, Ting-Ting Huang, Ji-Hua Li, Ling-Xiao Liao, Xue Meng, Xiang-Qian Wen, Zi-Na Sun, Qian Ma, Jian Huang, Tian-Hua
Published in
Andrology
Like the coronavirus disease 2019, the hepatitis B virus is also wreaking havoc worldwide, which has infected over 2 billion people globally. Using an experimental animal model, our previous research observed that the hepatitis B virus genes integrated into human spermatozoa can replicate and express after being transmitted to embryos. However, as ...
almutairi, mikhlid h. alsoraie, waad a. alrubie, turki m. alkhaldi, ahmad s. alhajri, nada s. alaujan, monira a. almutairi, manar h. almutairi, bader o.
Background/Objectives: Colon cancer (CC) in Saudi Arabia is associated with a high death rate and is commonly identified at a more progressive stage. Therefore, it is critical to identify and characterize potential novel cancer-specific biomarkers to enhance early CC diagnosis. The goal was to assess their potential use as cancer biomarkers for the...
