Stenhouse, Claire Halloran, Katherine M Newton, Makenzie G Gaddy, Dana Suva, Larry J Bazer, Fuller W
Published in
Biology of reproduction
Mineralization of the fetal mammalian skeleton requires a hypercalcemic gradient across the placenta from mother to fetus. However, the mechanisms responsible for maintaining the placental transport of calcium remain poorly understood. This study aimed to identify calcium and vitamin D regulatory pathway components in ovine endometria and placentae...
O'Neil, Eleanore V Spencer, Thomas E
Published in
Biology of reproduction
In ruminants, conceptus elongation requires the endometrium and its secretions. The amino acid, carbohydrate, and protein composition of the uterine lumen during early pregnancy has been defined in sheep; however, a comprehensive understanding of metabolomic changes in the uterine lumen is lacking, particularly with respect to lipids. Here, the lip...
Pierzchała, Dorota Liput, Kamila Korwin-Kossakowska, Agnieszka Ogłuszka, Magdalena Poławska, Ewa Nawrocka, Agata Urbański, Paweł Ciepłoch, Aleksandra Juszczuk-Kubiak, Edyta Lepczyński, Adam
...
Published in
International journal of molecular sciences
The molecular mechanism underlying embryonic implantation is vital to understand the correct communications between endometrium and developing conceptus during early stages of pregnancy. This study's objective was to determine molecular changes in the uterine endometrial proteome during the preimplantation and peri-implantation between 9 days (9D),...
Huhn, Oisín Zhao, Xiaohui Esposito, Laura Moffett, Ashley Colucci, Francesco Sharkey, Andrew M.
Published in
Frontiers in Immunology
Innate lymphoid cells (ILCs) are the most abundant immune cells in the uterine mucosa both before and during pregnancy. Circumstantial evidence suggests they play important roles in regulating placental development but exactly how they contribute to the successful outcome of pregnancy is still unclear. Uterine ILCs (uILCs) include subsets of tissue...
Cheng, Xianzhong Zhao, Qian Xu, Xia Guo, Wenwen Gu, Hongyuan Zhou, Rui Chen, Chen Ma, Dawei Wu, Yinan Ni, Jing
...
Published in
Frontiers in Oncology
Yolk sac tumors (YSTs) of the endometrium and the broad ligament are very rare, with only 29 cases and one case of each other reported before in the English literature. Due to lack of standard guidelines, the treatment strategies of these diseases are controversial. Here, we share two cases of YSTs originating from the endometrium and the broad lig...
Sauerbrun-Cutler, May-Tal Huber, Warren J Krueger, Paula M Sung, C James Has, Phinnara Sharma, Surendra
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
Clinical significance of endometrial and peripheral blood natural killer (NK) and regulatory T cells (Tregs) during frozen embryo transfer (FET) cycles has not been well characterized. Retrospective cohort study. Endometrial tissue was collected from infertility patients prior to a frozen embryo transfer cycle as part of an endometrial receptivity ...
Muro, Bruno Bracco Donatelli Leal, Diego Feitosa Carnevale, Rafaella Fernandes Torres, Mariana Andrade Mendonça, Maitê Vidal Nakasone, Denis Hideki Martinez, Cristian Hernando Garcia Ravagnani, Gisele Mouro Monteiro, Matheus Saliba Poor, André Pegoraro
...
Published in
Animal Reproduction
This study evaluated the effects of supplying altrenogest from day 6-12 of pregnancy on the endometrial glandular epithelium, corpora lutea (CL) morphology, and endometrial and CL gene expression. A total of 12 crossbred females (Landrace × Large White) were used. The females were assigned to 4 treatments according to a random design with a 2 × 2 f...
Tu, Jiajie Yang, Huan Chen, Yu Chen, Yu Chen, He Li, Zhe Li, Lei Zhang, Yuanyuan Chen, Xiaochun Yu, Zhiying
...
Published in
Frontiers in Endocrinology
The uterine endometrium, which lines the mammalian uterus, is essential for embryo implantation. This lining undergoes significant changes during sexual and menstrual cycles. The endometrium is also associated with hormone-related diseases such as endometriosis and endometrial cancer. Circular RNAs (circRNAs) play a role in various biological proce...
Navarro, Antonia Bariani, Maria Victoria Yang, Qiwei Al-Hendy, Ayman
Published in
Frontiers in Cell and Developmental Biology
Uterine fibroids (leiomyomas) are the most common benign gynecological tumors in women of reproductive age worldwide. They cause heavy menstrual bleeding, usually leading to severe anemia, pelvic pain/pressure, infertility, and other debilitating morbidities. Fibroids are believed to be monoclonal tumors arising from the myometrium, and recent stud...
Devis-Jauregui, Laura Eritja, Núria Davis, Meredith Leigh Matias-Guiu, Xavier Llobet-Navàs, David
Published in
Autophagy
Autophagy is a highly conserved catabolic process and a major cellular pathway for the degradation of long-lived proteins and cytoplasmic organelles. An increasing body of evidence has unveiled autophagy as an indispensable biological function that helps to maintain normal tissue homeostasis and metabolic fitness that can also lead to severe conseq...
