kathiravan, subban dhillon, prakriti zhang, tianshu nicholls, ian a.
Unsymmetrical urea derivatives are essential structural motifs in a wide array of biologically significant compounds. Despite the well-established methods for synthesizing symmetrical ureas, efficient strategies for the synthesis of unsymmetrical urea derivatives remain limited. In this study, we present a novel approach for the synthesis of unsymm...
gallo, simona folco, consolata beatrice crepaldi, tiziana
The MET receptor, commonly known as HGF (hepatocyte growth factor) receptor, is a focus of extensive scientific research. MET has been linked to embryonic development, tissue regeneration following injury, tumorigenesis, and cancer metastasis. These functions underscore its involvement in numerous cellular processes, including stemness, proliferati...
Henderson, Alisha Heaney, Liam M Rankin-Turner, Stephanie
Published in
Drug testing and analysis
Ambient ionisation mass spectrometry (AIMS) is a form of mass spectrometry whereby analyte ionisation occurs outside of a vacuum source under ambient conditions. This enables the direct analysis of samples in their native state, with little or no sample preparation and without chromatographic separation. The removal of these steps facilitates a muc...
Omomeji, Loveth Onifade, M K Onokwai, A O Atiba, J Salawu, E Y Joseph, O O
Published in
Materials Research Express
This research delves into the potential of expired Glavox tablets, containing Amoxicillin and Clavulanic acid, as environmentally friendly substances to inhibit corrosion on A36 carbon steel in solutions of 1M HCl and 3.65 wt% NaCl. The findings from weight loss experiments in 1M HCl indicated a decrease in the corrosion rate, dropping from 1.24 mm...
Montanari, Linda Royuela, Luis Mazzilli, Sara Vandam, Liesbeth Alvarez, Elena Llorens, Noelia Carapinha, Ludmila Grohmannova, Katerina Isajeva, Laura Ignataviciute, Lina
...
Published in
Journal of community psychology
Substance use is a global phenomenon that is particularly affecting the prison population. This study aimed to describe the prevalence of drug use among people in prison before and during incarceration in seven European countries and to compare it with the prevalence in the general population. Individual data collection was carried out between 2014...
hernández-cabré, laura ulldemolins-rams, marta vilanova-corsellas, judit torras, carles
A catheter is a device that is inserted into the venous system to infuse treatment with controlled doses per unit of time. The study of its interaction with blood flow cannot be easily analysed with common analytical methods or different visualization techniques in real life. Computational Fluid Dynamics has become a very useful tool in a wide vari...
smolobochkin, andrey gazizov, almir appazov, nurbol sinyashin, oleg burilov, alexander
The presented review systematizes and summarizes the data on the synthesis of pyrrolidine derivatives, which are precursors for obtaining drugs. Based on the analysis of published data, the most promising directions in the synthesis of biologically active compounds containing a pyrrolidine ring are identified. Stereoselective synthesis methods are ...
Algar, Jess L Lawes, Douglas J Carroll, Adam J Caldicott, David McLeod, Malcolm D
Published in
Drug testing and analysis
Drug checking is a harm reduction measure that provides people with the opportunity to confirm the identity and purity of substances before consumption. The CanTEST Health and Drug Checking Service is Australia's first fixed-site drug checking service, where clients can learn about the contents of the samples they provide while receiving tailored h...
palos, isidro gonzález-gonzález, alonzo paz-gonzález, alma d. espinoza-hicks, josé c. bandyopadhyay, debasish paniagua-castro, norma galeana-salazar, marlene s. castañeda-sánchez, jorge ismael luna-herrera, julieta rivera, gildardo
...
Mycetoma is currently considered as a neglected tropical disease. The incidence of mycetoma is unknown but most of the worldwide cases are present in the “mycetoma belt” including countries like Mexico, India, Senegal, and others. The treatment of mycetoma depends on the etiological agent responsible for the case. Treatment success reaches 60 to 90...
Sağlam Özkan, Yeşim Kara, Yeliz
Published in
Physica Scripta
Topological indices are used to convert a chemical structure into a real number, usually to study the physicochemical and biological properties of molecules. The groundwork is prepared for the interpretation of the obtained data by processing with Quantitative Structure Property/Activity Relationship (QSPR/QSAR). In this study, the drugs lorlatinib...
