Published in Psychophysiology
Overweight and obesity may damage the cerebrovascular architecture, resulting in a significant reduction in cerebral blood flow. To date, there have been few randomized clinical trials (RCT) examining whether obesity-related reductions in cerebral blood flow could be modified by weight loss. Further, it is unknown whether the behavioral interventio...
Published in The Plant journal : for cell and molecular biology
Polyploidy has played a crucial role in plant evolution, development and function. Synthetic autopolyploid represents an ideal system to investigate the effects of polyploidization on transcriptional regulation. In this study, we deciphered the impact of genome duplication at phenotypic and molecular levels in watermelon. Overall, 88% of the genes ...
Published in National Science Review
Allopolyploidy is an important process in plant speciation, yet newly formed allopolyploid species typically suffer from extreme genetic bottlenecks. One escape from this impasse might be homoeologous meiotic pairing, during which homoeologous exchanges (HEs) generate phenotypically variable progeny. However, the immediate genome-wide patterns and ...
Published in Children and youth services review
Although substantial investments in early childhood intervention have continued, whether gains are sustained past kindergarten for routinely implemented programs is a critical research need. Using data from the Chicago Longitudinal Study (CLS; N=1,539; 50.3% female; 92.9% African American and 7.1% Hispanic), an on-going investigation of the Child-P...
Published in Developmental cell
Replication-dependent histone genes often reside in tandemly arrayed gene clusters, hindering systematic loss-of-function analyses. Here, we used CRISPR/Cas9 and the attP/attB double-integration system to alter numbers and sequences of histone genes in their original genomic context in Drosophila melanogaster. As few as 8 copies of the histone gene...
Vitamin D has been identified as an important factor in healthy aging and is receiving growing attention in clinical research. Vitamin D is a fat-soluble molecule, which is synthesized by hepatic and renal or extra-renal hydroxylation into the active hormone 1,25-dihydroxyvitamin D (1,25(OH)2D). The main function of this metabolite is to regulate c...
Abstract Background and aim: Moderate alcohol consumption has been suggested to contribute to emotional well-being. However, the effects of moderate alcohol consumption on emotional well-being in common drinking situations and the influence of alcohol on physical well-being remain unclear. The aims of this thesis were 1) to further explore the acut...
A high EC results in loss of production and reduces growth. However, for quality reasons it can be beneficial to maintain a higher EC. In doing so a grower can take advantage of the difference between the plant’s day and night mechanisms.
Te hoge dosering van herbiciden kunnen soms leiden tot opbrengstderving. Dat blijkt uit een onderzoek door PPO-agv en CLM. Ze adviseren het LDS-systeem te combineren met een goede middelenkeuze en mechanische onkruidbestrijding, om het risico op gewasschade te beperken. Dat is ook nog eens goed voor de waterkwaliteit.
De N-gebruiksnorm voor lelie is vastgesteld op 145 kg N per ha op zand, löss en veen en 155 kg per ha op klei. Telers ervaren de gebruiksnorm voor m.n. het nieuwe assortiment snelgroeiende cultivars als te laag voor een optimale gewas- en bolgroei, omdat deze cultivars een veel hogere bolopbrengst en biomassa hebben. Dit project had als doel de gem...
