Published in Frontiers in Molecular Biosciences
Increasingly studies have shown that the formation mechanism of many human diseases is very complex, which is determined by environmental factors and genetic factors rather than fully following Mendel’s genetic law of inheritance. Long non-coding RNA (lncRNA) is a class of endogenous non-protein coding RNA with a length greater than 200 nt, which h...
Published in The Journal of infectious diseases
Lassa virus (LASV) causes mild to severe hemorrhagic fever disease in humans. Strain 13/N guinea pigs are highly susceptible to infection with LASV strain Josiah (clade IV), providing a critical model system for therapeutics and vaccine development. To develop additional models of disease, we detail the clinical course in guinea pigs infected with ...
Published in Acta odontologica Scandinavica
To determine the prevalence and severity of dry mouth by age, gender, presence of disease, and medication intake for patients aged 18 years and over, seeking primary health care on the west coast of Sweden (Region of Västra Götaland, VGR). Cross-sectional study conducted among patients (n = 374, age ≥ 18) visiting primary health care providers (n =...
Published in Frontiers in Cell and Developmental Biology
Mitochondria are cell organelles that play pivotal roles in maintaining cell survival, cellular metabolic homeostasis, and cell death. Mitochondria are highly dynamic entities which undergo fusion and fission, and have been shown to be very motile in vivo in neurons and in vitro in multiple cell lines. Fusion and fission are essential for maintaini...
Published in Frontiers in Nutrition
Published in Frontiers in Microbiology
Published in Frontiers in Cell and Developmental Biology
Published in Frontiers in Marine Science
The decline of elkhorn coral, Acropora palmata, has been ongoing for decades, but the causes of decline and the resulting population status continue to be topics of study. Past efforts to categorize stressors have ranged from spatially and/or temporally focused efforts that detect local stressors but may miss broader patterns to meta-analyses that ...
Published in Frontiers in Marine Science
Published in Frontiers in Cell and Developmental Biology
Aging is characterised by the progressive accumulation of cellular dysfunction, stress, and inflammation. A large body of evidence implicates mitochondrial dysfunction as a cause or consequence of age-related diseases including metabolic disorders, neuropathies, various forms of cancer and neurodegenerative diseases. Because neurons have high metab...
