Tallmadge, Rebecca L. Laverack, Melissa Cronk, Brittany Venugopalan, Roopa Martins, Mathias Zhang, XiuLin Elvinger, François Plocharczyk, Elizabeth Diel, Diego G.
Published in
Microbiology Spectrum
In the present study, we assessed the diagnostic sensitivity and determined the viral RNA load and infectivity of SARS-CoV-2 in paired respiratory (nasopharyngeal and anterior nares) and oral samples (saliva and sublingual swab). Samples were collected from 77 individuals of which 75 were diagnosed with COVID-19 and classified as symptomatic (n = 2...
Halliday, Alice Masonou, Tereza Tolosa-Wright, Mica R Guo, Yanping Hoang, Long Parker, Robert Boakye, Aime Takwoingi, Yemisi Badhan, Amarjit Jain, Pooja
...
Published in
The Journal of infectious diseases
Diagnosis of paucibacillary tuberculosis (TB) including extrapulmonary TB is a significant challenge, particularly in high-income, low-incidence settings. Measurement of Mycobacterium tuberculosis (Mtb)-specific cellular immune signatures by flow cytometry discriminates active TB from latent TB infection (LTBI) in case-control studies; however, the...
Wolff, Nicole Eberlein, Matthias Stroth, Sanna Poustka, Luise Roepke, Stefan Kamp-Becker, Inge Roessner, Veit
Published in
Frontiers in Psychiatry
Liu, Shan-peng Li, Xiao-min Liu, Dan-man Xie, Shu-huan Zhang, Shao-bo Li, Yu Xie, Ze-feng
Published in
Frontiers in Oncology
Esophageal cancer (ESCA) is a common malignant tumor with poor prognosis. Accumulating evidence indicates an important role of lysosomal-associated membrane protein 2 (LAMP2) in the progression and development of various cancers. In this study, we obtained RNA-sequencing raw count data and the corresponding clinical information for ESCA samples fro...
Wu, Shenghui Su, Xiaojun Ye, Qianyu Wei, Yongcheng Gao, Yifang Huang, Mingchuan Chen, Yanxu Wang, Jiali Zhang, Qiang Fu, Qian
...
Published in
Frontiers in Immunology
Objectives B cell-activating factor (BAFF), which is critical in the activation and differentiation of B cells, is a candidate diagnostic and predictive biomarker for antibody-mediated rejection (ABMR). We aimed to investigate the value of serum soluble BAFF (sBAFF) for the diagnosis and risk stratification of ABMR after kidney transplantation. Met...
Ding, Junping Zhao, Shubin Chen, Xianhua Luo, Changjun Peng, Jinjian Zhu, Jiantan Shen, Yongqi Luo, Zhou Chen, Jianlin
Published in
Frontiers in Genetics
Background: Semaphorin 5B (SEMA5B) has been described to be involved in the development and progression of cancer. However, the potential diagnostic and prognosis roles and its correlation with tumor-infiltrating immune cells in KIRC have not been clearly reported yet. Methods: The mRNA level of SEMA5B was analyzed via the TCGA and GTEx database as...
Contreras Garcia, Maria Walshe, Emily Steketee, Pieter C. Paxton, Edith Lopez-Vidal, Javier Pearce, Michael C. Matthews, Keith R. Ezzahra-Akki, Fatima Evans, Alec Fairlie-Clark, Karen
...
Published in
Frontiers in Veterinary Science
Animal trypanosomiasis (AT) is a significant livestock disease, affecting millions of animals across Sub-Saharan Africa, Central and South America, and Asia, and is caused by the protozoan parasites Trypanosoma brucei, Trypanosoma vivax, and Trypanosoma congolense, with the largest economic impact in cattle. There is over-reliance on presumptive ch...
Ezzikouri, Sayeh Nourlil, Jalal Tsukiyama-Kohara, Kyoko Kohara, Michinori El Ossmani, Hicham Windisch, Marc P Benjelloun, Soumaya
Published in
Journal of biomolecular structure & dynamics
Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by severe acute respiratory coronavirus 2 (SARS-CoV-2). This virus is capable of human-to-human transmission, and is spreading rapidly round the globe, with markedly high fatality rates. Unfortunately, there are neither vaccines nor specific therapies available to combat it, ...
Zhou, Wen-Da Shao, Lei Dong, Li Zhang, Rui-Heng Li, Yi-Fan Li, He-Yan Wu, Hao-Tian Shi, Xu-Han Wei, Wen-Bin
Published in
Frontiers in Oncology
For uveal melanoma (UM) patients, it is significant to establish diagnosis and prognosis evaluation systems through imaging techniques. However, imaging examinations are short of quantitative biomarkers and it is difficult to finish early diagnosis of UM. In order to discover new molecular biomarkers for the diagnosis and prognostic evaluation of U...
Antoine, Delphine Mohammadi, Moein Vitt, Madison Dickie, Julia Marie Jyoti, Sharmin Sultana Tilbury, Maura A Johnson, Patrick A Wawrousek, Karen E Wall, J Gerard
Published in
ACS sensors
Rapid, sensitive, on-site identification of SARS-CoV-2 infections is an important tool in the control and management of COVID-19. We have developed a surface-enhanced Raman scattering (SERS) immunoassay for highly sensitive detection of SARS-CoV-2. Single-chain Fv (scFv) recombinant antibody fragments that bind the SARS-CoV-2 spike protein were iso...
