This paper proposes a new magnetic model self-identification technique for synchronous machines to build the flux-map look-up tables (LUTs). Provided the shaft is free to turn, an alternating self-acceleration and deceleration sequence is envisaged for identification without a dedicated experimental rig or additional hardware. Respect to previous w...
The proper characterization of protein-ligand interfaces is essential for structural biology, with implications ranging from the fundamental understanding of biological processes to pharmacology. Nuclear magnetic resonance is a powerful technique for such studies. We propose a novel approach to the direct determination of the likely pose of a pepti...
Published in The FEBS journal
The membrane-proximal C-terminal region (Pro-C) is important for the regulation of G-protein-coupled receptors (GPCRs), but the binding of the Pro-C region to a cytosolic regulator has not been structurally analyzed. The chemokine receptor CCR2 is a member of the GPCR superfamily, and the Pro-C region of CCR2 binds to the cytosolic regulator FROUNT...
The stator and rotor yoke in a switched reluctance motor form magnetic circuit parts that are typically shared by different phases. If these parts saturate due to the excitation of one phase, this will lead to a change of the magnetic characteristics of all other phases sharing these parts. In several position-sensorless methods, cross-saturation l...
Published in Journal of Biomolecular NMR
Cross-saturation experiments allow the identification of the contact residues of large protein complexes (MW>50 K) more rigorously than conventional NMR approaches which involve chemical shift perturbations and hydrogen-deuterium exchange experiments [Takahashi et al. (2000) Nat. Struct. Biol., 7, 220–223]. In the amide proton-based cross-saturatio...
Published in Journal of Biomolecular NMR
Cross-saturation experiments have been shown to give accurate information regarding the interacting surfaces in protein-protein and protein-RNA complexes. The rate of magnetization transfer depends on a number of factors including geometry, spin topology, and effective correlation times. To assess the influence of these variables on such experiment...
