(1) Background: Electrostatics plays a capital role in protein–protein and protein–ligand interactions. Implicit solvent models are widely used to describe electrostatics and complementarity at interfaces. Electrostatic complementarity at the interface is not trivial, involving surface potentials rather than the charges of surfacial contacting atom...
In this paper, the clean high yielding, synthesis, and structure of the tetraphosphine ligand, 1,1′,2,2′-tetrakis-(di-isopropyl-phosphino)ferrocene, (tdipf), is described. In addition, improved synthesis methods for 1,1′,2,2′-tetrakis(diphenylphosphino)ferrocene, (tppf), and 2,2′-bis-(diphenylphosphino)-1,1′-dibromoferrocene are also reported, and ...
The objective of this study is to investigate the impact of different pH values and chloropropene flow rates on the erosion–corrosion behavior of 316L stainless steel. The influence of various factors on the surface morphology was analyzed using scanning electron microscopy, X-ray powder diffractometry, and electrochemical impedance spectroscopy te...
Background and Objectives: Robot-assisted extravesical ureteral reimplantation (REVUR) has been described as valuable alternative to open reimplantation in the pediatric population. This study aimed to report the outcome of REVUR in children with complex obstructed megaureter (COM) needing ureteral dismembering and/or tapering. Materials and Method...
The solubilization of poorly water-soluble natural bioactive compounds remains a significant challenge. This study aims to design a ternary inclusion system to enhance the solubility of the poorly water-soluble compound Neohesperidin (NH). Soluble ternary cyclodextrin complexations (t-CDs) containing NH, 2-hydroxypropyl-β-cyclodextrin (HP-β-CD), an...
Published in Birth (Berkeley, Calif.)
Healthcare for childbearing women with complex needs demands a multi-disciplinary approach requiring transitions between care providers, paradigms, and models of care. These transitions may create disconnects between women and the maternity care "system." Poorly managed care transitions can lead to women becoming hostage to the power struggles betw...
The novel hydrosoluble silver coordination polymer [Ag(NO3)(μ-1κN;2κN′,N″-TPMOH)]n (1) (TPMOH = tris(1H-pyrazol-1-yl)ethanol) was obtained and characterized. While single crystal X-ray diffraction analysis of compound 1 disclosed an infinite 1D helical chain structure in the solid state, NMR analysis in polar solvents confirmed the mononuclear natu...
ADP-ribosylation is a ubiquitous modification of proteins and other targets, such as nucleic acids, that regulates various cellular functions in all kingdoms of life. Furthermore, these ADP-ribosyltransferases (ARTs) modify a variety of substrates and atoms. It has been almost 60 years since ADP-ribosylation was discovered. Various ART structures h...
Projekt KOLEJE NA KOLEJÍCH pracuje s myšlienkou nového študentského moderného kampusu spojeného s ekonomicky výhodným sociálnym bývaním a nadčasovou budovou coworkingu s výhľadom priamo na koľajovú trať. Nový vytvorený poloverejný priestor vyčlenený štyrmi novými budovami a historickou zrenovovanou sýpkou ponúka atraktívne prostredie, ktoré slúži a...
Předmětem návrhu je administrativní budova na pozemku v Praze ve Vršovicích. Návrh navazuje na urbanistické řešení studie vypracované na FA ČVUT. Budova má celkem 5 nadzemních a jedno podzemní podlaží. Stavba je navržena do tvaru nepravoúhlého písmene U a je rozdělena na tři hlavní hmoty – krajní ramena U jsou vyšší a jsou spojeny nižším spojovacím...
