Ancelin, Marie-Laure Carriere, Isabelle Artero, Sylvaine Maller, Jerome J Meslin, Chantal Dupuy, Anne-Marie Ritchie, Karen Ryan, Joanne Chaudieu, Isabelle
Published in
European journal of psychotraumatology
背景: 可能由于影像学研究和人群, 临床表现, 遗传易损性及对照选择的异质性, 关于创伤后脑结构改变的研究结果不一。本研究考查了创伤和再体验症状是否与灰质体积的特定变化有关, 以及这种变化是否依据5-HTTLPR基因型而不同。方法: 使用结构性核磁共振成像 (MRI) 获取了377名社区老年居民的解剖学图像。使用FreeSurfer软件得出了22个亚区体积的分区定量估计。终身创伤使用经验证的Watson的PTSD量表, 根据DSM标准评估所经历过最严重的创伤。以年龄, 性别, 全脑体积, 头部外伤及并发症为分析的调节变量。结果: 在212名报告终身创伤的参与者中, 35.4%报告有再体验症状, 1.9%的严重程度足以满足PTSD完全临界值的标准。仅在具有SS 5-HTTLPR基因型的参与者中...
González-Brusi, Leopoldo Algarra, Blanca Moros-Nicolás, Carla Izquierdo-Rico, Mª José Avilés, Manuel Jiménez-Movilla, Maria
Published in
Biomolecules
The oviduct plays important roles in reproductive events: sperm reservoir formation, final gamete maturation, fertilization and early embryo development. It is well known that the oviductal environment affects gametes and embryos and, ultimately, the health of offspring, so that in vivo embryos are better in terms of morphology, cryotolerance, preg...
Borges, Marcus K Aprahamian, Ivan Romanini, Carla V Oliveira, Fabiana M Mingardi, Silvana V B Lima, Natália A Cecato, Juliana F Petrella, Marina Oude Voshaar, Richard C
Published in
Aging & mental health
Accumulating evidence shows depression as a risk factor for frailty, but studies are mainly population-based and widely differ in their assessment of either depression or frailty. We investigated the association between depression and frailty among geriatric outpatients using different assessment instruments for both conditions. Among 315 geriatric...
Yen, Yung-Feng Tsai, Yi-Fan Su, Vincent Yi-Fong Chan, Shang-Yih Yu, Wen-Ruey Ho, Hsuan Hou, Chun-Mei Chen, Chu-Chieh Woung, Lin-Chung Huang, Sheng-Jean
...
Published in
Journal of medical Internet research
Telehealth is a recommended method for monitoring the progression of nonsevere infections in patients with COVID-19. However, telehealth has not been widely implemented to monitor SARS-CoV-2 infection in quarantined individuals. Moreover, studies on the cost-effectiveness of quarantine measures during the COVID-19 pandemic are scarce. In this cohor...
Lindblad, Anna Kaucher, Simone Jaehn, Philipp Kajüter, Hiltraud Holleczek, Bernd Lissner, Lauren Becher, Heiko Winkler, Volker
Published in
International journal of environmental research and public health
Previous studies have shown that the incidence of gastric cancer (GC), and particularly intestinal GC, is higher among resettlers from the former Soviet Union (FSU) than in the general German population. Our aim was to investigate if the higher risk remains over time. GC cases between 1994 and 2013, in a cohort of 32,972 resettlers, were identified...
Brasky, Theodore M Bethea, Traci N Wesselink, Amelia K Wegienka, Ganesa R Baird, Donna D Wise, Lauren A
Published in
American journal of epidemiology
Uterine leiomyomata (UL) are associated with severe reproductive morbidity and are the primary indication for hysterectomy in the United States. A recent prospective cohort study of Black women reported positive associations between intakes of marine-sourced ω-3 fatty acids and UL risk. We examined whether intakes of dietary fat were associated wit...
Gilsenan, Alicia Midkiff, Kirk Harris, David McQuay, Lisa Hunter, Shannon Kellier-Steele, Nicole Andrews, Elizabeth
Published in
Pharmacoepidemiology and drug safety
During preclinical testing, teriparatide caused a dose-dependent increase in the incidence of osteosarcoma in rats. This study compared the incidence rate of osteosarcoma among patients aged ≥65 years treated with teriparatide vs a matched-comparator cohort. This population-based comparative-cohort study matched exposure details for each teriparati...
Chen, Kuan-Fu Tsai, Meng-Ying Wu, Chin-Chieh Han, Shih-Tsung
Published in
Journal of intensive care medicine
Sepsis is a major cause of morbidity and mortality worldwide. With the advance of medical care, the mortality of sepsis has decreased in the past decades. Many treatments and diagnostic tools still lack supporting evidence. We conducted a retrospective population-based cohort study with propensity score matched subcohorts based on a prospectively c...
Björkenstam, Emma Helgesson, Magnus Amin, Ridwanul Mittendorfer-Rutz, Ellenor
Published in
The British journal of psychiatry : the journal of mental science
Mental disorders are associated with an elevated risk for suicide attempt and suicide. Whether the strength of the associations also holds for refugees is unclear. To examine the relationship between specific mental disorders and suicide attempt and suicide in refugees and Swedish-born individuals. This longitudinal cohort study included 5 083 447 ...
Groot, Jonathan Nybo Andersen, Anne-Marie Blegvad, Christoffer Pinot de Moira, Angela Skov, Lone
Published in
Journal of the American Academy of Dermatology
Tobacco smoking is implicated in psoriasis among adults. To determine whether prenatal, infantile, and childhood tobacco exposure increase risk of pediatric psoriasis. Data from Danish National Birth Cohort participants were collected at approximately gestational week 12 and when the children were approximately 6 months and 11 years of age. In tota...