Kristoffersen, Ann Helen Stavelin, Anne V. Ajzner, Eva Kristensen, Gunn B.B. Sandberg, Sverre Van Blerk, Marjan Kitchen, Steve Kesseler, Dagmar Woods, Timothy A.L. Meijer, Piet
...
Published in
Clinical Chemistry and Laboratory Medicine (CCLM)
Background Correct handling and storage of blood samples for coagulation tests are important to assure correct diagnosis and monitoring. The aim of this study was to assess the pre-analytical practices for routine coagulation testing in European laboratories. Methods In 2013–2014, European laboratories were invited to fill in a questionnaire addres...
Chalayer, Emilie Tardy-Poncet, Brigitte Montmartin, Aurélie Boussoualim, Karima Genthon, Alexis Tardy, Bernard
Published in
British journal of haematology
Reiffel, James A.
Published in
The Journal of Innovations in Cardiac Rhythm Management
Yagneswar, Hamsini Todd, Jeffrey M Sharkey, Leslie C Rendahl, Aaron Tart, Kelly
Published in
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Clot waveforms are generated by coagulation analyzers, such as the ACL-TOP, that utilize photo-optical turbidimetric methods to measure prothrombin time (PT) and activated partial thromboplastin time (aPTT), which are standard clotting tests (SCTs). Additional quantitative clot waveform analysis (CWA) parameters include maximum velocity of the PT c...
Yang, W Hosgood, G Luobikis, K Paul, A
Published in
Australian veterinary journal
To determine the agreement, sensitivity, specificity and accuracy of prothrombin (PT) and activated partial thromboplastin time (aPTT) using the point-of-care analyser SCA2000™ with IDEXX Coag Dx™ cartridges against a reference laboratory (STAGO Start 4®) in canine blood. Citrated blood samples from 47 dogs were submitted for PT and aPTT measuremen...
Howley, Isaac W Haut, Elliott R Jacobs, Lenwoth Morrison, Jonathan J Scalea, Thomas M
Published in
Trauma surgery & acute care open
Thomboelastography (TEG) is a whole blood measure of coagulation which was originally described in the 1950s. However, it has only been in the last few decades that assays have become accessible and viable as a point-of-care test. Following the observation that hemorrhagic shock is associated with an intrinsic coagulopathy, TEG has been used as a m...
Somani, Vaibhav Amarapurkar, Deepak Shah, Apurva
Published in
Journal of clinical and experimental hepatology
Conventional coagulation tests (CCTs) in patients with cirrhosis only assess procoagulant factors and are poor predictors of bleeding risk. In spite of this knowledge, they are routinely used prior to invasive procedures, and attempts are made to correct these abnormalities before invasive procedures. These practices are not supported by the eviden...
Sarode, Karan Syed, Saad Tyroch, Alan Mukherjee, Debabrata
Published in
Cardiovascular & hematological disorders drug targets
This review provides a summary of clinical trials utilizing VETs in the aforementioned clinical scenarios, and suggests that VETs have demonstrated a capability to identify coagulopathies, utility in guiding algorithms to reduce the amount of transfusions, and a limited ability to predict bleeding events or mortality.
Ergin, Merve Erdogan, Serpil Akturk, Onur Erel, Ozcan
Published in
Clinical Chemistry and Laboratory Medicine (CCLM)
Background: This research investigated the effects of the transport of blood samples between centers/laboratories by car on coagulation tests. Methods: Five tubes of blood samples were taken from 20 healthy volunteers. The samples consisted of a baseline (control) group, centrifuged and noncentrifuged transported samples; centrifuged and noncentrif...
Douxfils, Jonathan Chatelain, Bernard Chatelain, Christian Dogné, Jean-Michel Mullier, François
Published in
Thrombosis and haemostasis
Assessment of plasma concentration/effect of edoxaban may be useful in some situations. Also, clinicians need to know how routine coagulation assays are influenced. It was our aim to determine coagulation tests useful for the assessment of edoxaban's pharmacodynamics and provide recommendations for the interpretation of haemostasis diagnostic tests...