de Freitas Pereira, Maíra Cohen, David Auer, Lucas Aubry, Nathalie Bogeat-Triboulot, Marie-Béatrice Buré, Cyril Engle, Nancy L Jolivet, Yves Kohler, Annegret Novák, Ondřej
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Published in
The Plant journal : for cell and molecular biology
Tree growth and survival are dependent on their ability to perceive signals, integrate them, and trigger timely and fitted molecular and growth responses. While ectomycorrhizal symbiosis is a predominant tree-microbe interaction in forest ecosystems, little is known about how and to what extent it helps trees cope with environmental changes. We hyp...
Yang, Yang Xiao, Bing Feng, Xin Chen, Yue Wang, Qunhui Fang, Jing Zhou, Ping Wei, Xiang Cheng, Lin
Published in
Frontiers in Cardiovascular Medicine
Background Human aortic valve stenosis (AS) and insufficiency (AI) are common diseases in aging population. Identifying the molecular regulatory networks of AS and AI is expected to offer novel perspectives for AS and AI treatment. Methods Highly correlated modules with the progression of AS and AI were identified by weighted genes co-expression ne...
Wang, Yu Wei, Jinxue Chen, Ting Yang, Xiao Zhao, Liansheng Wang, Min Dou, Yikai Du, Yue Ni, Rongjun Li, Tao
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Published in
Frontiers in Psychiatry
Introduction Previous studies on transcriptional profiles suggested dysregulation of multiple RNA species in major depressive disorder (MDD). However, the interaction between different types of RNA was neglected. Therefore, integration of different RNA species in transcriptome analysis would be helpful for interpreting the functional readout of the...
Cao, Liru Zhang, Pengyu Lu, Xiaomin Wang, Guorui Wang, Zhenhua Zhang, Qianjin Zhang, Xin Wei, Xin Mei, Fujian Wei, Li
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Published in
International Journal of Molecular Sciences
OSCAs are hyperosmolality-gated calcium-permeable channel proteins. In this study, two co-expression modules, which are strongly associated with maize proline content, were screened by weighted correlation network analysis, including three ZmOSCA family members. Phylogenetic and protein domain analyses revealed that 12 ZmOSCA members were classifie...
Xiao, Junhui Li, Fang Yang, Qianzhao Zeng, Xue-Feng Ke, Zun-Ping
Published in
Journal of cellular physiology
Dilated cardiomyopathy (DCM) is a heart disease that injured greatly to the people wordwide. Systemic co-expression analysis for this cancer is still limited, although massive clinic experiments and gene profiling analyses had been well performed previously. Here, using the public RNA-Seq data "GSE116250" and gene annotation of Ensembl database, we...
Zou, Yong Jing, Luanlian
Published in
Oncology Letters
Adrenocortical carcinoma (ACC) is a rare and aggressive cancer with a high relapse rate and limited treatment options. Therefore, the identification of potential prognostic markers in patients with ACC may improve early detection, survival rates and may additionally provide novel insights into the early detection of recurrence. In the present study...
Li, Xiao Hu, Wei-Wei Wang, Li Yang, Xiang-Hui
Published in
Cancer biomarkers : section A of Disease markers
Oral squamous cell carcinoma is a malignant tumor which is particularly common in the developing world, mostly in older males. Although gene expression analyses had been performed previously, to our best knowledge, systemic co-expression analysis for this disease is still lacking to date. In this study, we built the co-expression modules with the h...
Hou, Wanwan Zhu, Sibo Shang, Jun Li, Bin Zheng, Yuanting Yu, Ying Shi, Leming
Published in
Current pharmaceutical biotechnology
Drug metabolizing enzymes and transporters (DMETs) play crucial roles in drug absorption and disposition. Species differences in the interaction of compounds with DMETs may contribute to the accuracy of animal models in predicting human responses in clinical studies. Thus it is important to clarify the expression heterogeneity of DMETs between huma...
Te, Jerez A AbdulHameed, Mohamed Diwan M Wallqvist, Anders
Published in
Journal of applied toxicology : JAT
Organ injuries caused by environmental chemical exposures or use of pharmaceutical drugs pose a serious health risk that may be difficult to assess because of a lack of non-invasive diagnostic tests. Mapping chemical injuries to organ-specific histopathology outcomes via biomarkers will provide a foundation for designing precise and robust diagnost...