Plasmacytoid dendritic cell neoplasm or BPCDN (blastic plasmacytoid dendritic cell neoplasm) is a rare and very aggressive malignant hematological pathology. It affects more frequently the male gender from the sixth decade of life. It generally manifests with skin lesions with subsequent involvement of the bone marrow, peripheral blood and neuromen...
Though a large number of techniques are available for the study of aquatic bacteria, the aim of this study was to establish a technique for analysing free-living and biofilm prokaryotic cells through laboratory assays. In particular, we wished to analyse the efficiency of ultrasound to detach and disrupt biofilm, to obtain an efficient stain treatm...
Introducción: la citomorfología por cytospin (CC) es, hasta el momento, el método patrón oro para la detección de linfoblastos en el líquido cefalorraquídeo (LCR) en leucemia linfoblástica aguda (LLA) y para guiar las decisiones terapéuticas. La citometría de flujo (CMF) es un método utilizado para identificar el linaje de células en muestras de mé...
Poor assimilation of food in the body leads to malnutrition or undernutrition (UN), a pathological condition with varying degrees and clinical manifestations.In recent years, a new test using in vivo somatic mutation detection based on the gene glycosylphosphatidylinositol Class A (Pig-a) has been developed. This gene is essential for the synthesis...
Resumen La asimilación deficiente de alimentos por el organismo conduce a un estado patológico con distintos grados y manifestaciones clínicas, conocido como desnutrición. En los últimos años ha surgido un nuevo ensayo in vivo de detección de mutación somática basado en el gen glucosilfosfatidilinositol de clase A (Pig-a). Este gen es necesario par...
The advance in the knowledge of the pathophysiology of multiple myeloma has allowed the approach to the understanding of its heterogeneity in terms of clinical, cytomorphological, phenotypic, biochemical, genetic and molecular behavior, contributing to the development of new treatments and the establishment of models that point to a chronicity of t...
Leukemias are the leading cause of death by disease in children in Colombia, even represent half of pediatric cancer deaths in the country. Currently, the World Health Organization, together with international experts, has updated the classification and diagnosis criteria for hematolymphoid neoplasias. These criteria, based on all available diagnos...
Introducción: La enfermedad granulomatosa crónica (EGC) es una inmunodeficiencia primara caracterizada por alteración en la funcionalidad de neutrófilos, fundamental para defensa contra infecciones en humanos. La prueba del nitroazul de tetrazolio (NBT) es útil para el diagnóstico, destacándose al presente las técnicas por citometría de flujo como ...
