Published in Anticancer research
Amplification of chromosome 8q with locus 8q24 is the most common copy number aberration, and is associated with tumour progression and chemoresistance. The study used paired samples of biopsy and surgical material from 60 patients with breast cancer. The amplification status of 8q was determined using a CytoScan HD Array microarray; complete trans...
Published in Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia
The aim of this cytogenetic study is to confirm the significance of chromosome 3 loss (monosomy 3) and of the gain of chromosome 8 as prognostic markers in histopathological samples of enucleated eyes with uveal melanoma in the Czech population. This is a retrospective study of 52 enucleated eyes. Chromosome 3 and 8 status were tested by CISH, and ...
Published in Brain Sciences
The 8p inverted duplication/deletion is a rare chromosomal rearrangement clinically featuring neurodevelopmental delay, mild to severe cognitive impairment, heart congenital defects and brain abnormalities. Patients affected also present typical facial dysmorphisms and skeletal malformations, and it is thought that the composite clinical picture ma...
Published in Cancer genomics & proteomics
Chondroid syringoma is a rare benign tumor emanating from sweat glands. Although rearrangements of the pleomorphic adenoma gene 1 (PLAG1) have been reported in such tumors, information on PLAG1 fusion genes is very limited. Cytogenetic, fluorescence in situ hybridization, RNA sequencing, array comparative genomic hybridization, reverse transcriptio...
Review on t(3;8)(p25;q24), with data on clinics
Review on t(X;8)(q24;q24), with data on clinics.
Review on t(6;8)(p21;q24), with data on clinics, and the genes involved.
Review on t(3;8)(p25;q24), with data on clinics
Review on t(1;8)(p21-22;q24), with data on clinics, and the genes involved.
Review on t(1;8)(p11-13;q24), with data on clinics, and the genes involved.
