Sparks, Sierra Hayes, Genevieve Pinto, Joana Bulte, Daniel
Published in
Frontiers in Physiology
Introduction Smooth muscle is integral to multiple autonomic systems, including cerebrovascular dynamics through vascular smooth muscle cells and in ocular muscle dynamics, by regulating pupil size. In the brain, smooth muscle function plays a role in cerebrovascular reactivity (CVR) that describes changes in blood vessel calibre in response to vas...
Fedriga, Marta Martini, Silvia Iodice, Francesca G Sortica da Costa, Cristine Pezzato, Stefano Moscatelli, Andrea Beqiri, Erta Czosnyka, Marek Smielewski, Peter Agrawal, Shruti
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Deranged cerebral autoregulation (CA) is associated with worse outcome in adult brain injury. Strategies for monitoring CA and maintaining the brain at its 'best CA status' have been implemented, however, this approach has not yet developed for the paediatric population. This scoping review aims to find up-to-date evidence on CA assessment in child...
Magnusson, Gustav Engström, Maria Georgiopoulos, Charalampos Cedersund, Gunnar Tobieson, Lovisa Tisell, Anders
Published in
Frontiers in Medicine
Introduction Cerebrovascular reactivity imaging (CVR) is a diagnostic method for assessment of alterations in cerebral blood flow in response to a controlled vascular stimulus. The principal utility is the capacity to evaluate the cerebrovascular reserve, thereby elucidating autoregulatory functioning. In CVR, CO2 gas challenge is the most prevalen...
Carter, Sarah C. Cucchiara, Brett Reehal, Navpreet Hamilton, Katherine Kaiser, Eric A. Favilla, Christopher G.
Published in
Frontiers in Neurology
Introduction Calcitonin gene-related peptide (CGRP) plays an important role in cerebral vasodilation, so here we aim to quantify the impact of CGRP monoclonal antibody (mAb) therapy on cerebral hemodynamics. Methods In 23 patients with chronic and episodic migraine, cerebral hemodynamic monitoring was performed (1) prior to and (2) 3-months into CG...
Ovsenik, Ana
Izhodišča: Za aortno stenozo (AS) je značilna obstrukcija iztoka krvi iz levega prekata, ki lahko povzroči motnjo prekrvavitve tarčnih organov, vključno z možgani. V raziskavi smo predpostavili, da hemodinamske motnje pri AS povzročijo okvaro v delovanju mehanizmov regulacije možganskega krvnega pretoka (MKP). Namen naše raziskave je bil ovrednotit...
Hoogeveen, E S Pelzer, N Ghariq, E van Osch, M J P Dahan, A Terwindt, G M Kruit, M C
Published in
Headache
This study aimed to compare cerebrovascular reactivity between patients with migraine and controls using state-of-the-art magnetic resonance imaging (MRI) techniques. Migraine is associated with an increased risk of cerebrovascular disease, but the underlying mechanisms are still not fully understood. Impaired cerebrovascular reactivity has been pr...
Aslanyan, Vahan Mack, Wendy J Ortega, Nancy E Nasrallah, Ilya M Pajewski, Nicholas M Williamson, Jeff D Pa, Judy
Published in
Alzheimer's & dementia : the journal of the Alzheimer's Association
Vascular risk factors contribute to cognitive decline suggesting that maintaining cerebrovascular health could reduce dementia risk. The objective of this study is to evaluate the association of cerebrovascular reactivity (CVR), a measure of brain blood vessel elasticity, with mild cognitive impairment (MCI) and dementia. Participants were enrolled...
Gomez, Alwyn Marquez, Izabella Froese, Logan Bergmann, Tobias Sainbhi, Amanjyot Singh Vakitbilir, Nuray Islam, Abrar Stein, Kevin Y Ibrahim, Younis Zeiler, Frederick A
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Peer reviewed: True / Publication status: Published / Near-infrared spectroscopy (NIRS) regional cerebral oxygen saturation (rSO2)-based cerebrovascular reactivity (CVR) monitoring has enabled entirely non-invasive, continuous monitoring during both acute and long-term phases of care. To date, long-term post-injury CVR has not been properly charact...
Wheeler, Gregory James
Vascular contributions to cognitive impairment and dementia (VCID) are the second leading cause of dementia and increasing in prevalence as lifespans increase. Clinical MRI traditionally relies on structural abnormalities to identify this vascular dysfunction but lacks microstructure and functional information that could be critical for early ident...
Engstrom, Allison C
Background: Deficits in cerebrovascular reactivity (CVR) to experimentally-induced hypercapnia are observed in older adults with mild cognitive impairment (MCI), suggesting a role for CVR as a biomarker of vascular contributions to MCI. Spontaneous CVR at rest has also been studied without experimental induction of hypercapnia. The present study so...
