Packer, John Gubieda, Alicia G Brooks, Aaron Deutz, Lars N Squires, Iolo Ellison, Shona Schneider, Claudia Naganathan, Sundar Ram Wollman, Adam J M Dickinson, Daniel J
...
Published in
bioRxiv : the preprint server for biology
Atypical protein kinase C (aPKC) is a major regulator of cell polarity. Acting in conjunction with Par6, Par3 and the small GTPase Cdc42, aPKC becomes asymmetrically localised and drives the polarisation of cells. aPKC activity is crucial for its own asymmetric localisation, suggesting a hitherto unknown feedback mechanism contributing to polarisat...
Remy, Ophélie Santin, Yoann G. Jonckheere, Veronique Tesseur, Coralie Kaljević, Jovana Van Damme, Petra Laloux, Géraldine
Published in
Journal of Bacteriology
In bacteria, cell poles are crucial areas where “hub” proteins orchestrate lifecycle events through interactions with multiple partners at specific times. While most bacteria exhibit one “old” and one “new” pole, inherited from the previous division event, setting polar identity poses challenges in bacteria with non-binary division. This study expl...
Pinot, Mathieu Le Borgne, Roland
The Notch communication pathway, discovered in Drosophila over 100 years ago, regulates a wide range of intra-lineage decisions in metazoans. The division of the Drosophila mechanosensory organ precursor is the archetype of asymmetric cell division in which differential Notch activation takes place at cytokinesis. Here, we review the molecular mech...
Remy, Ophélie Santin, Yoann G. Jonckheere, Veronique Tesseur, Coralie Kaljević, Jovana Van Damme, Petra Laloux, Géraldine
In bacteria, cell poles function as subcellular compartments where proteins localize during specific lifecycle stages, orchestrated by polar "hub" proteins. Whereas most described bacteria inherit an "old" pole from the mother cell and a "new" pole from cell division, generating cell asymmetry at birth, non-binary division poses challenges for esta...
Zhang, Lili Wei, Xiangyun
Published in
Biological reviews of the Cambridge Philosophical Society
Neurulation transforms the neuroectoderm into the neural tube. This transformation relies on reorganising the configurational relationships between the orientations of intrinsic polarities of neighbouring cells. These orientational intercellular relationships are established, maintained, and modulated by orientational cell adhesions (OCAs). Here, u...
Beier, Marcel Pascal Jinno, Chiyo Noda, Natsumi Nakamura, Kohei Sugano, Sumio Suzuki, Yutaka Fujita, Tomomichi
Published in
Frontiers in Plant Science
Abscisic acid (ABA)-mediated abiotic stress tolerance causes plant growth inhibition. Under such stress conditions, some mosses generate de novo stress-resistant stem cells, also called brood cells or brachycytes, that do not exist under normal conditions. However, the cell physiological basis of the growth inhibition and the stem cell formation is...
Yu, Fan Yang, Song Ni, Hua Heng, Dai Wu, Xuemei Yang, Mulin Zhang, Xinming Cao, Yuxin Pei, Yandong An, Di
...
Published in
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
O-GlcNAcylation functions as a cellular nutrient and stress sensor and participates in almost all cellular processes. However, it remains unclear whether O-GlcNAcylation plays a role in the establishment and maintenance of cell polarity, because mice lacking O-GlcNAc transferase (OGT) are embryonically lethal. Here, a mild Ogt knockout mouse model ...
Kingma, E. (author)
All living systems possess the ability to evolve. This ability has allowed life to adopt a large diversity of shapes, colors, sizes and lifestyles. However, despite being a fundamental property of life, our knowledge of what makes living systems evolvable is limited. The fact that evolution can be sometimes be hopelessly unpredictable while in othe...
Uwamichi, Masahito Miura, Yusuke Kamiya, Ayako Imoto, Daisuke Sawai, Satoshi
Published in
Frontiers in Cell and Developmental Biology
Amoeboid cell movement and migration are wide-spread across various cell types and species. Microscopy-based analysis of the model systems Dictyostelium and neutrophils over the years have uncovered generality in their overall cell movement pattern. Under no directional cues, the centroid movement can be quantitatively characterized by their persis...
Kiel, M Wuebker, S Remy, M T Riemondy, K A Smith, F Carey, C M Williams, T Van Otterloo, E
Published in
Journal of dental research
Coordinated mineralization of soft tissue is central to organismal form and function, while dysregulated mineralization underlies several human pathologies. Oral epithelial-derived ameloblasts are polarized, secretory cells responsible for generating enamel, the most mineralized substance in the human body. Defects in ameloblast development result ...
