Cooperation of gene regulatory networks and phytohormones in cell development and morphogenesis
Published in Frontiers in Plant Science
Cooperation of gene regulatory networks and phytohormones in cell development and morphogenesis
Correlations among Antibiotic Resistance Genes, Mobile Genetic Elements and Microbial Communities in Municipal Sewage Tr...
Published in International journal of environmental research and public health
Municipal sewage treatment plants (MSTPs) are environmental pools for antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs), which is cause for growing environmental-health concerns. In this study, the effects of different wastewater treatment processes on microbial antibiotic resistance in four MSTPs were investigated. PCR, q-...
Progress in biological and medical research in the deep underground: an update
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Published in Frontiers in Public Health
As the growing population of individuals residing or working in deep underground spaces for prolonged periods, it has become imperative to understand the influence of factors in the deep underground environment (DUGE) on living systems. Heping Xie has conceptualized the concept of deep underground medicine to identify factors in the DUGE that can h...
Highly Expressed LINC00958 Modulates the Growth and Epithelial-Mesenchymal Transition of Bladder Cancer Cells Through SA...
Published in Cancer biotherapy & radiopharmaceuticals
Objective: To determine the expression of LINC00958 (BLACAT2) in bladder cancer (BC), the most common malignancy in the urinary system, and to determine its exact mechanism of action, so as to provide novel references for future clinical diagnosis and treatment of BC and lay a foundation for the follow-up research on LINC00958. Materials and Method...
miR-4286 promotes prostate cancer progression by targeting the expression of SALL1.
Published in The journal of gene medicine
Prostate cancer (PCa) is a serious health threat for humans worldwide. Recent studies have revealed that microRNAs are associated with the progression of human cancers, including PCa. However, no study has been performed aiming to investigate the role of microNA-4286 (miR-4286) on PCa. A quantitative reverse transcriptase-polymerase chain reaction ...
LncRNA AL161431.1 predicts prognosis and drug response in head and neck squamous cell carcinoma
Published in Frontiers in Oncology
Background Long non-coding RNAs (lncRNAs) are increasingly recognized as essential players in various biological processes due to their interactions with DNA, RNA, and protein. Emerging studies have demonstrated lncRNAs as prognostic biomarkers in multiple cancers. However, the prognostic effect of lncRNA AL161431.1 in head and neck squamous cell c...
Comprehensive analysis of REST corepressors (RCORs) in pan-cancer
Published in Frontiers in Cell and Developmental Biology
REST corepressors (RCORs) are the core component of the LSD1/CoREST/HDACs transcriptional repressor complex, which have been revealed differently expressed in various cancers, but the therapeutic and prognostic mechanisms in cancer are still poorly understood. In this study, we analyzed expression, prognostic value, molecular subtypes, genetic alte...
GID2 Interacts With CDKN3 and Regulates Pancreatic Cancer Growth and Apoptosis.
Published in Laboratory investigation; a journal of technical methods and pathology
Dysregulation of deubiquitinase or ubiquitinase-mediated protein expression contributes to various diseases, including cancer. In the present study, we identified GID2, a subunit of the glucose-induced degradation-deficient (GID) complex that functions as an E3 ubiquitin ligase, as a potential key candidate gene in pancreatic cancer (PC) progressio...
Cell size regulation: molecular mechanisms and physiological importance
Published in Frontiers in Cell and Developmental Biology
α-Ketoglutarate stimulates cell growth through the improvement of glucose and glutamine metabolism in C2C12 cell culture...
Published in Frontiers in Nutrition
Introduction Cellular adaptation to physical training and energy metabolism play an important role during physical exercise. This study sought to investigate the effects of α-KG on cell growth and energy metabolism in C2C12 cell culture. Methods C2C12 cells were cultured in media pretreated without (control) or with α-KG at different concentrations...
