merighi, stefania nigro, manuela travagli, alessia fernandez, mercedes vincenzi, fabrizio varani, katia pasquini, silvia borea, pier andrea salati, simona cadossi, ruggero
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Alzheimer’s disease (AD) is a neurodegenerative pathology covering about 70% of all cases of dementia. It is associated with neuroinflammation and neuronal cell death, which are involved in disease progression. There is a lack of effective therapies, and halting this process represents a therapeutic challenge. Data in the literature suggest several...
Fang, Wei Liu, Ying Xu, Chun Luo, Xingguang Wang, Kesheng
Published in
International journal of environmental research and public health
Feature selection is essentially the process of picking informative and relevant features from a larger collection of features. Few studies have focused on predictors for current e-cigarette use among U.S. adults using feature selection and machine learning (ML) approaches. This study aimed to perform feature selection and develop ML approaches in ...
levy, i. altaras, anat binyamini, lior sagi-assif, orit izraely, sivan cooks, tomer kobiler, oren gerlic, motti kelson, itzhak witz, isaac p.
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Background/Objective: In this study, for the first time, we examined and compared the sensitivity of four patient-derived cutaneous melanoma cell lines to alpha radiation in vitro and analyzed it in view of cell nucleus area and the formation of double-strand breaks (DSB). Melanoma cells sensitivity to alpha radiation was compared to photon radiati...
Haavik, Heidi Niazi, Imran Khan Amjad, Imran Kumari, Nitika Ghani, Usman Ashfaque, Moeez Rashid, Usman Navid, Muhammad Samran Kamavuako, Ernest Nlandu Pujari, Amit N
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Published in
Brain sciences
This study aimed to elucidate the mechanisms of chiropractic care using resting electroencephalography (EEG), somatosensory evoked potentials (SEPs), clinical health assessments (Fitbit), and Patient-reported Outcomes Measurement Information System (PROMIS-29). Seventy-six people with chronic low back pain (mean age ± SD: 45 ± 11 years, 33 female) ...
Pan, Yue Fei, Lei Wang, Shihua Chen, Hua Jiang, Changqing Li, Hong Wang, Changsong Yang, Yao Zhang, Qinggao Chen, Yongwen
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Published in
Frontiers in Immunology
Background Cell death plays an essential role in carcinogenesis, but its function in the recurrence and postoperative prognosis of head and neck cancer (HNC), which ranks as the 7th most common malignancy globally, remains unclear. Methods Data from five main subtypes of HNC related single-cell RNA sequencing (scRNA-seq) were recruited to establish...
Andrushko, Yaryna Lanza, Stephanie T
Published in
International journal of environmental research and public health
This study enhances the understanding of resilience in forced migration through a psychological lens, highlighting the importance of identifying resilience determinants and evidence-based interventions. By fostering resilience, policymakers and practitioners can support the well-being and adaptive capacities of forcibly displaced Ukrainians, promot...
chandra, anantika kesavardhana, sannula
Zoonotic viruses originating from reservoir hosts, such as bats and birds, often cause severe illness and outbreaks amongst humans. Upon zoonotic virus transmission, infected cells mount innate immune responses that include the activation of programmed cell death pathways to recruit innate immune cells to the site of infection and eliminate viral r...
chipón, carina riffo, paula ojeda, loreto salas, mónica burgos, rafael a. ehrenfeld, pamela lópez-muñoz, rodrigo zambrano, angara
Lung cancer (LC) is the leading cause of cancer death worldwide. LC can be classified into small-cell lung cancer (SCLC) and non-small-cell lung cancer (NSCLC), with the last subtype accounting for approximately 85% of all diagnosed lung cancer cases. Despite the existence of different types of treatment for this disease, the development of resista...
Sun, Jiasen Ren, Hui Wang, Jiawen Xiao, Xiang Zhu, Lin Wang, Yanyan Yang, Lili
Published in
Frontiers in Cell and Developmental Biology
CHAC1, an essential regulator of oxidative stress and ferroptosis, is increasingly recognized for its significant roles in these cellular processes and its impact on various human diseases and cancers. This review aims to provide a comprehensive overview of CHAC1’s molecular functions, regulatory mechanisms, and effects in different pathological co...
Ko, Chung-Nga Yang, Chao
Published in
Frontiers in Immunology