Liu, Heqi Wang, Fang Zhang, Jianmin Gao, Zhengzheng
Published in
Frontiers in Pediatrics
Background Thoracoscopy is considered the surgical method of choice for addressing a wide range of conditions in neonates. However, there is a lack of experience in anesthesia management for this procedure. On reviewing the newborns who had undergone thoracoscopic surgery at our medical center, some had developed edema after surgery. After excludin...
Bracko, Oliver Harraz, Osama F.
Published in
Frontiers in Molecular Neuroscience
Eide, Per Kristian
Published in
Frontiers in Cellular Neuroscience
Idiopathic normal pressure hydrocephalus (iNPH) is a subtype of dementia with overlap toward Alzheimer's disease. Both diseases show deposition of the toxic metabolites amyloid-β and tau in brain. A unique feature with iNPH is that a subset of patients may improve clinically following cerebrospinal fluid (CSF) diversion (shunt) surgery. The patient...
Sirago, Giuseppe Toniolo, Luana Crea, Emanuela Giacomello, Emiliana
Published in
International journal of food sciences and nutrition
Sarcopenia starts around the age of 40, causes the loss of 8% of muscle mass every 10 years, and is accompanied by functional deficit, chronic low-grade inflammation, and can result in several negative health outcomes. Considering the early and gradual onset of sarcopenia, the time window of the potential interventions could be crucial for the exer...
Kemp, Scott S. Penn, Marlena R. Koller, Gretchen M. Griffin, Courtney T. Davis, George E.
Published in
Frontiers in Cell and Developmental Biology
In this work, we sought to investigate the direct effects of proinflammatory mediators on lymphatic endothelial cell (LEC) capillaries and whether they might induce regression. Our laboratory has developed novel in-vitro, serum-free, lymphatic tubulogenesis assay models whereby human LEC tube networks readily form in either three-dimensional collag...
Eide, Per Kristian Hansson, Hans-Arne
Published in
Frontiers in Molecular Neuroscience
Idiopathic intracranial hypertension (IIH) is a neurological disease characterized by symptoms and signs of increased intracranial pressure (ICP) of unknown cause. Most attention has been given to the role of cerebrospinal fluid (CSF) disturbance and intracranial venous hypertension caused by sinus vein stenosis. We previously proposed that key pat...
Goltstein, Lia C M J Rooijakkers, Maxim J P Görtjes, Natasha C C Akkermans, Reinier P Zegers, Erwin S Pisters, Ron van Wely, Marleen H van der Wulp, Kees Drenth, Joost P H van Geenen, Erwin J M
...
Published in
Circulation. Cardiovascular interventions
Heyde syndrome is the co-occurrence of aortic stenosis and gastrointestinal bleeding secondary to angiodysplasias. Surgical aortic valve replacement effectively reduces bleeding, but the effects of transcatheter aortic valve implantation (TAVI) are largely unknown. This study aimed to describe the reduction of gastrointestinal bleeding in patients ...
Le, D. Elizabeth Zhao, Yan Kaul, Sanjiv
Published in
Frontiers in Cardiovascular Medicine
Background There is persistent coronary vasomotor tone during myocardial ischemia, despite ongoing coronary arteriolar dilatation. The mechanism underlying this vasodilatory tone, which can be unmasked by coronary vasodilators, is unclear. We hypothesized that persistent microvascular resistance during myocardial ischemia occurs at the level of cap...
Hack, Remco J Gravesteijn, Gido Cerfontaine, Minne N Hegeman, Ingrid M Mulder, Aat A Lesnik Oberstein, Saskia A J Rutten, Julie W
Published in
Stroke
To determine whether extremely mild small vessel disease (SVD) phenotypes can occur in NOTCH3 variant carriers from Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) pedigrees using clinical, genetic, neuroimaging, and skin biopsy findings. Individuals from CADASIL pedigrees fulfilling criteria for...
Harraz, Osama F Klug, Nicholas R Senatore, Amanda J Hill-Eubanks, David C Nelson, Mark T
Published in
Circulation research
Capillaries are equipped to sense neurovascular coupling agents released onto the outer wall of a capillary, translating these external signals into electrical/Ca2+ changes that play a crucial role in blood flow regulation and ensuring that neuronal demands are met. However, control mechanisms attributable to forces imposed onto the lumen are less ...
