Chao, Min-Wu Lin, Tony Eight HuangFu, Wei-Chun Chang, Chao-Di Tu, Huang-Ju Chen, Liang-Chieh Yen, Shih-Chung Sung, Tzu-Ying Huang, Wei-Jan Yang, Chia-Ron
...
Published in
Journal of enzyme inhibition and medicinal chemistry
The STE20 kinase family is a complex signalling cascade that regulates cytoskeletal organisation and modulates the stress response. This signalling cascade includes various kinase mediators, such as TAOK1 and MAP4K5. The dysregulation of the STE20 kinase pathway is linked with cancer malignancy. A small-molecule inhibitor targeting the STE20 kinase...
Çakmak, M E Kaya, S B Bostan, Ö C Aktaş, Ö Ö Damadoğlu, E Karakaya, G Kalyoncu, A F
Published in
European annals of allergy and clinical immunology
Introduction. Hypersensitivity reactions to chemotherapeutic drugs are increasing all over the world, and desensitization to them has become the standard treatment approach. This study aimed to evaluate the characteristics of chemotherapeutic drug hypersensitivity reactions and the outcome of desensitization procedures. Methods. Between January 201...
Ramadan, Khaled Gomes, Bruno Pipkin, Mauricio Olkowicz, Mariola Bojko, Barbara Mbadjeu Hondjeu, Arnaud Romeo Keshavjee, Shaf Waddell, Thomas Pawliszyn, Janusz Cypel, Marcelo
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Published in
The Journal of thoracic and cardiovascular surgery
To determine the dose-limiting toxicity of oxaliplatin chemotherapy delivered by in vivo lung perfusion (IVLP). To allow assessment of subacute toxicities, we aimed to develop a 72-hour porcine IVLP survival model. In total, 12 Yorkshire male pigs were used. Left lung IVLP was performed for 3 hours. At 72 hours postoperatively, computed tomography ...
Amarakoon, Darshika Lou, Zhiyuan Lee, Wu-Joo Smolensky, Dmitriy Lee, Seong-Ho
Published in
Journal of the science of food and agriculture
Sorghum is one of the most widely cultivated crops, and is used in foods, domestic animal feedstuffs, alcohol production, and biofuels. Recently, many research groups have demonstrated that sorghum contains various components that are strongly associated with the prevention of major human chronic diseases such as obesity, diabetes, atherosclerosis,...
Hall, Daniel L Neil, Jordan M Ostroff, Jamie S Hawari, Saif O'Cleirigh, Conall Park, Elyse R
Published in
Journal of health psychology
One third of smokers diagnosed with cancer continue smoking, perhaps due to low perceived cancer-related benefits of cessation. To examine perceived cancer-related benefits of quitting among newly diagnosed cancer patients who smoke and associations with quit intentions, baseline measures from patients (N = 303) enrolled in a randomized controlled ...
Sastra, Lenni Büssing, Arndt Chen, Ching-Huey Yen, Miaofen Lin, Esther Ching-Lan
Published in
Journal of transcultural nursing : official journal of the Transcultural Nursing Society
Introduction: Although Muslims constitute nearly one fourth of the global population, many non-Muslims are not familiar with Islam. To address this unique need from such a specific cultural context, the present study aimed to examine the spiritual needs and influencing factors of Indonesian Muslims with cancer. Method: A cross-sectional research de...
Singh, Ashutosh Nayak, Namyashree Rathi, Preeti Verma, Deepanshu Sharma, Rohit Chaudhary, Ashun Agarwal, Alka Tripathi, Yamini Bhushan Garg, Neha
Published in
Seminars in cancer biology
The commensal microbiome of humans has co-evolved for thousands of years. The microbiome regulates human health and is also linked to several diseases, including cancer. The advances in next-generation sequencing have significantly contributed to our understanding of the microbiome and its association with cancer and cancer therapy. Recent studies ...
Pizzagalli, Mattia D Bensimon, Ariel Superti-Furga, Giulio
Published in
The FEBS journal
This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily of transporter proteins and their roles in human cells. The SLC superfamily currently includes 458 transport proteins in 65 families that carry a wide variety of substances across cellular membranes. While members of this superfamily are found throughout c...
Levit, R Savoy de Giori, G de Moreno de LeBlanc, A LeBlanc, J G
Published in
Journal of applied microbiology
Lactic acid bacteria (LAB), widely used as starter cultures for the fermentation of a large variety of food, can improve the safety, shelf life, nutritional value and overall quality of the fermented products. In this regard, the selection of strains delivering health-promoting compounds is now the main objective of many researchers. Although most ...
Sun, Qinyu Song, You Jin Prasanth, Kannanganattu V
Published in
Wiley interdisciplinary reviews. RNA
Long noncoding RNAs (lncRNAs) are RNA transcripts longer than 200 nucleotides that do not code for proteins. LncRNAs play crucial regulatory roles in several biological processes via diverse mechanisms and their aberrant expression is associated with various diseases. LncRNA genes are further subcategorized based on their relative organization in t...
