Lerner, Avi Kewada, Drashti Ahmed, Ayan Hardy, Kate Christian, Mark Franks, Stephen
Published in
International Journal of Molecular Sciences
Polycystic ovary syndrome (PCOS) is a common endocrinopathy that is associated with an adverse metabolic profile including reduced postprandial thermogenesis. Although abnormalities in adipose tissue function have been widely reported in women with PCOS, less is known about direct effects of androgen on white and, particularly, brown adipocytes. Th...
Primc, Gregor
Published in
Polymers
A review of the most significant scientific achievements in the field of surface modification of polyamides by non-equilibrium plasma treatments is presented. Most authors employed atmospheric pressure discharges and reported improved wettability. The super-hydrophilic surface finish was only achieved using a low-pressure plasma reactor and prolong...
Senthivinayagam, Subramanian Serbulea, Vlad Upchurch, Clint M Polanowska-Grabowska, Renata Mendu, Suresh K Sahu, Srabani Jayaguru, Prathiba Aylor, Kevin W Chordia, Mahendra D Steinberg, Limor
...
Published in
Molecular metabolism
Brown adipose tissue (BAT) is specialized in thermogenesis. The conversion of energy into heat in brown adipocytes proceeds via stimulation of β-adrenergic receptor (βAR)-dependent signaling and activation of mitochondrial uncoupling protein 1 (UCP1). We have previously demonstrated a functional role for pannexin-1 (Panx1) channels in white adipose...
Nishio, Miwako Saeki, Kumiko
Published in
Cells
Brown adipose tissue (BAT), which is a thermogenic fat tissue originally discovered in small hibernating mammals, is believed to exert anti-obesity effects in humans. Although evidence has been accumulating to show the importance of BAT in metabolism regulation, there are a number of unanswered questions. In this review, we show the remaining myste...
Wołek, Barbara Werłos, Mateusz Komander, Magdalena Kudelko, Agnieszka
Published in
Molecules (Basel, Switzerland)
Two series of novel (symmetrical and unsymmetrical) quinazolinylphenyl-1,3,4-oxadiazole derivatives were synthesized using palladium-catalyzed Suzuki cross-coupling reactions. The presented synthetic methodology is based on the use of bromine-substituted 2-phenyl-4-N,N-dimethylaminoquinazolines and either a boronic acid pinacol ester or a diboronic...
Munro, Patrick Dufies, Océane Rekima, Samah Loubat, Agnès Duranton, Christophe Boyer, Laurent Pisani, Didier F
Published in
American journal of physiology. Endocrinology and metabolism
Numerous studies have shown that the recruitment and activation of thermogenic adipocytes, which are brown and beige/brite, reduce the mass of adipose tissue and normalize abnormal glycemia and lipidemia. However, the impact of these adipocytes on the inflammatory state of adipose tissue is still not well understood, especially in response to endot...
Yoneshiro, Takeshi Rodríguez-Rodríguez, Rosalía Betz, Matthias Johannes Rensen, Patrick C. N.
Published in
Frontiers in Endocrinology
Pinckard, Kelsey M Shettigar, Vikram K Wright, Katherine R Abay, Eaman Baer, Lisa A Vidal, Pablo Dewal, Revati S Das, Devleena Duarte-Sanmiguel, Silvia Hernández-Saavedra, Diego
...
Published in
Circulation
Background: Brown adipose tissue (BAT) is an important tissue for thermogenesis, making it a potential target to decrease the risks of obesity, type 2 diabetes, and cardiovascular disease (CVD), and recent studies have also identified BAT as an endocrine organ. While BAT has been implicated to be protective in cardiovascular disease, to this point ...
Yi, Danielle Nguyen, Hai P Dinh, Jennie Viscarra, Jose A Xie, Ying Lin, Frances Zhu, Madeleine Dempersmier, Jon M Wang, Yuhui Sul, Hei Sook
...
Published in
eLife
Brown adipose tissue is a metabolically beneficial organ capable of dissipating chemical energy into heat, thereby increasing energy expenditure. Here, we identify Dot1l, the only known H3K79 methyltransferase, as an interacting partner of Zc3h10 that transcriptionally activates the Ucp1 promoter and other BAT genes. Through a direct interaction, D...
Schellenberger, Sven Shi, Kilin Michler, Fabian Lurz, Fabian Weigel, Robert Koelpin, Alexander
Published in
Sensors (Basel, Switzerland)
In hospitals, continuous monitoring of vital parameters can provide valuable information about the course of a patient's illness and allows early warning of emergencies. To enable such monitoring without restricting the patient's freedom of movement and comfort, a radar system is attached under the mattress which consists of four individual radar m...
