Huang, Amy Huaishiuan Liu, Ye Hsien, Yenh-Chen Hsu, Tzu-Chun Yen, Debra Hsu, Wan-Ting Lin, Hsin-Yang Chen, Shyr-Chyr Lee, Chien-Chang
Published in
Journal of intensive care medicine
The impact of gastrointestinal bleeding (GIB) on outcomes of patients with bloodstream infection (BSI) has not been studied. We aim to evaluate the risk factors and survival impact of GIB on the outcome of BSI. This study was conducted prospectively at National Taiwan University Hospital Yunlin Branch between January 1, 2015, and December 31, 2016....
Wang, Cuicui Hao, Wei Jin, Yan Shen, Cuihua Wang, Bo
Published in
Microbial drug resistance (Larchmont, N.Y.)
Objective: Optimal dosing regimens for achieving a positive clinical outcome were simulated for seven antibiotics commonly used to treat bloodstream infections (BSIs) in adults. Methods and Results: Pharmacokinetic/pharmacodynamic (PK/PD) modeling was used to simulate 17 regimens, including meropenem, imipenem, cefepime, ceftazidime, piperacillin-t...
Jiang, Jie She, Bo Zheng, Rui
Published in
Infection and Drug Resistance
Eggerthella lenta is part of the normal bacterial flora of the intestinal tract, but may cause life-threatening infections. E. lenta has been isolated from blood, abscesses, wounds, skin ulcers, and intra-abdominal infections. However, due to historical difficulties with laboratory identification by conventional biochemical methods, some cases of E...
Sirard, Stéphanie Abou Chakra, Claire Nour Langlois, Marie-France Perron, Julie Carignan, Alex Valiquette, Louis
Published in
Antibiotics
The impact of adjusted treatment on clinical outcomes in patients with severe obesity is unclear. This study included adults with severe obesity admitted for bloodstream infections between 2005 and 2015. The patients were grouped according to the percentage of the appropriateness of the dosage of their antimicrobial treatment: 80–100% = good, 20–79...
Ji, Joyce Klaus, Jeff Burnham, Jason P Michelson, Andrew McEvoy, Colleen A Kollef, Marin H Lyons, Patrick G
Published in
Chest
Bloodstream infections (BSIs) are common after hematopoietic stem cell transplantation (HSCT) and are associated with increased long-term morbidity and mortality. However, short-term outcomes related to BSI in this population remain unknown. More specifically, it is unclear whether choices related to empiric antimicrobials for potentially infected ...
Zhang, Piaopiao Wang, Jie Hu, Hangbin Zhang, Sheng Wei, Juying Yang, Qing Qu, Tingting
Published in
Infection and Drug Resistance
Purpose The aim was to examine the clinical characteristics and risk factors for bloodstream infection (BSI) due to carbapenem-resistant Klebsiella pneumoniae (CRKP) in patients with hematologic malignancies. Materials and Methods A single-centre, retrospective case–control study representing 734 patients with hematologic malignancies between Janua...
Cooper, Emily Jones, Leah Joseph, Annie Allison, Rosie Gold, Natalie Larcombe, James Moore, Philippa McNulty, Cliodna A. M.
Published in
Antibiotics
Background: To inform interventions to improve antimicrobial use in urinary tract infections (UTIs) and contribute to a reduction in Escherichia coli bloodstream infection, we explored factors influencing the diagnosis and management of UTIs in primary care. Design: Semi-structured focus groups informed by the Theoretical Domains Framework. Setting...
Labi, Appiah-Korang Nielsen, Karen L. Marvig, Rasmus L. Bjerrum, Stephanie Enweronu-Laryea, Christabel Bennedbæk, Marc Newman, Mercy J. Ayibor, Prosper K. Andersen, Leif P. Kurtzhals, Jørgen A.L.
...
Published in
Emerging Infectious Diseases
We sequenced 29 carbapenemase-producing Klebsiella pneumoniae isolates from a neonatal intensive care unit in Ghana. Twenty-eight isolates were sequence type 17 with bla OXA-181 and differed by 0–32 single-nucleotide polymorphisms. Improved surveillance and infection control are needed to characterize and curb the spread of multidrug-resistant orga...
Messina, Julia A Moehring, Rebekah W Schmader, Kenneth E Anderson, Deverick J
Published in
Infection and Drug Resistance
Purpose We investigated the association between location of acquisition (LOA) of gram-positive (GP) bloodstream infections (BSI) in community hospitals and clinical outcomes. Methods We performed a multicenter cohort study of adult inpatients with GP BSI in nine community hospitals from 2003 to 2006. LOA was defined by CDC criteria: 1) community-ac...
Butler-Laporte, Guillaume Yansouni, Cedric P Paquette, Katryn Lawandi, Alexander Stabler, Sarah N Akhter, Murtaza Davidson, Adam C Gavric, Marko Jinah, Rehman Saeed, Zahid
...
Published in
Open Forum Infectious Diseases
Background Of all microbiological tests performed, blood cultures have the most impact on patient care. Timely results are essential, especially in the management of sepsis. While there are multiple available blood culture systems on the market, they have never been compared in a prospective study in a critically ill population. Methods We performe...
