Chan, Eric C Sun, Yuting Aitchison, Katherine J Sivapalan, Sudhakar
Published in
JMIR formative research
Bipolar disorder is a chronic, progressive illness characterized by recurrent episodes of mania and depression. Self-report scales have historically played a significant role in the monitoring of bipolar symptoms. However, these tools rely on episodic memory, which can be unreliable and do not allow the clinician to monitor brief episodic symptoms ...
Rostalski, Tim Schmidt, Silke Muehlan, Holger
Published in
International journal of environmental research and public health
Our ambulatory assessment study explores the impact of the weather on the mental well-being of people with increased susceptibility. Participants with hay fever (n = 28) were assessed three times a day over a period of two weeks. Self-reported assessments covered different indicators of mental well-being, including momentary affect, subjective heal...
Hopp, Sarah C
Published in
Journal of neuroscience research
Calcium (Ca2+ ) is a ubiquitous mediator of a multitude of cellular functions in the central nervous system (CNS). Intracellular Ca2+ is tightly regulated by cells, including entry via plasma membrane Ca2+ permeable channels. Of specific interest for this review are L-type voltage-dependent Ca2+ channels (L-VDCCs), due to their pleiotropic role in ...
Omer, Elad Braw, Yoram Amiaz, Revital Ravona-Springer, Ramit
Published in
International journal of geriatric psychiatry
Despite their impact on daily functioning, we have limited understanding of the executive functioning of older adults with bipolar disorder (OABD). Even less is known about the possible differences in the executive functioning of OABD and older adults with unipolar depression (OADEP). After excluding acutely ill patients, the executive functioning ...
Wang, Qiu-Wen Lu, Si-Yao Liu, Yao-Nan Chen, Yun Wei, Hui Shen, Wei Chen, Yan-Fen Fu, Chong-Lei Wang, Ying-Han Dai, Anbang
...
Published in
Proceedings of the National Academy of Sciences of the United States of America
Synaptotagmin-7 (Syt7) probably plays an important role in bipolar-like behavioral abnormalities in mice; however, the underlying mechanisms for this have remained elusive. Unlike antidepressants that cause mood overcorrection in bipolar depression, N-methyl-d-aspartate receptor (NMDAR)-targeted drugs show moderate clinical efficacy, for unexplaine...
Johansen, Kirsten Kjaer Hounsgaard, Lise Frandsen, Tove Faber Fluttert, Frans A J Hansen, Jens Peter
Published in
Journal of psychiatric and mental health nursing
WHAT IS ALREADY KNOWN ON THE SUBJECT?: Understanding the need for psychoeducation and management strategies in relapse prevention, for individuals with schizophrenia or bipolar disorder. Interventions for individuals with severe mental illness, especially schizophrenia, often requires support from family or social network to successfully improve me...
Galimberti, Cesare Caricasole, Valentina Bosi, Monica F Viganò, Caterina A Ketter, Terence A Dell'Osso, Bernardo
Published in
Early intervention in psychiatry
Up to just over half of bipolar disorder (BD) patients report at least one-lifetime anxiety disorder (AD). In some, anxiety represents the earliest psychiatric manifestation, prior to any mood episode. We sought to investigate prevalence of AD subtypes as first psychiatric manifestations and AD's relations with duration of untreated illness (DUI) a...
van Neerven, Thomas Bos, Dienke J van Haren, Neeltje Em
Published in
Neuroscience and biobehavioral reviews
Deficiencies in Theory of Mind (ToM) are consistently found in individuals with schizophrenia (SZ), major depressive disorder (MDD), and bipolar disorder (BD). However, the character of these deficits and their role in the pathogenesis of mental illness remains poorly understood. This systematic review synthesizes the available secondary literature...
Dollins, D Eric Xiong, Jian-Ping Endo-Streeter, Stuart Anderson, David E Bansal, Vinay S Ponder, Jay W Ren, Yi York, John D
Published in
The Journal of biological chemistry
Inositol polyphosphate 1-phosphatase (INPP1) is a prototype member of metal-dependent/lithium-inhibited phosphomonoesterase protein family defined by a conserved three-dimensional core structure. Enzymes within this family function in distinct pathways including inositide signaling, gluconeogenesis, and sulfur assimilation. Using structural and bio...
Xi, Caixi Lai, Jianbo Du, Yanli Ng, Chee H Jiang, Jiajun Wu, Lingling Zhang, Peifen Xu, Yi Hu, Shaohua
Published in
Journal of affective disorders
Reward circuit dysfunction underlies the pathogenesis of bipolar disorder (BD). This study aims to investigate whether nucleus accumbens (NAcc) and ventromedial prefrontal cortex (vmPFC), two key reward regions for BD, have resting-state dysfunctional connectivity with other brain regions in depressed and euthymic BD. 40 bipolar depressive (DE), 20...
