Uporaba pretočne citometrije za določanje N-glikolilneuraminske kisline pri ovarijskih celicah kitajskega hrčka
Published in Molecules (Basel, Switzerland)
Taxol®, which is also known as paclitaxel, is a chemotherapeutic agent widely used to treat different cancers. Since the discovery of its antitumoral activity, Taxol® has been used to treat over one million patients, making it one of the most widely employed antitumoral drugs. Taxol® was the first microtubule targeting agent described in the litera...
Progress in metabolic engineering and synthetic and systems biology has made bioproduction an increasingly attractive and competitive strategy for synthesizing biomolecules, recombinant proteins and biofuels from renewable feedstocks. Yet, due to poor productivity, it remains difficult to make a bioproduction process economically viable at large sc...
Published in Medicina (Kaunas, Lithuania)
Background and objectives: Expandable cages are frequently used to reconstruct the anterior spinal column after a corpectomy. In this retrospective study, we evaluated the perioperative advantages and disadvantages of corpectomy reconstruction with an expandable cage. Materials and Methods: Eighty-six patients (45 male and 41 female patients, mediu...
Published in The Journal of biological chemistry
Understanding enzymatic breakdown of plant biomass is crucial to develop nature-inspired biotechnological processes. Lytic polysaccharide monooxygenases (LPMOs) are microbial enzymes secreted by fungal saprotrophs involved in carbon recycling. LPMOs modify biomass by oxidatively cleaving polysaccharides thereby enhancing the efficiency of glycoside...
Published in Biotechnology progress
Biotechnology advances have allowed bacteria, yeasts, plants, mammalian and insect cells to function as heterologous protein expression systems. Recently, microalgae have gained attention as an innovative platform for recombinant protein production, due to low culture media cost, compared to traditional systems, as well as the fact that microalgae ...
Published in Biotechnology and bioengineering
In this study a simplified temperature model for raceway reactors is developed, allowing to determine the temperature of the microalgae culture as a function of reactor design and environmental conditions. The model considers the major phenomena taking place in raceway reactors, especially heat absorption by radiation and heat losses by evaporation...
Published in Nanotoxicology
Whereas nanotoxicity is intensely studied in mammalian systems, our knowledge of desired or unwanted nano-based effects for microbes is still limited. Fungal infections are global socio-economic health and agricultural problems, and current chemical antifungals may induce adverse side-effects in humans and ecosystems. Thus, nanoparticles are discus...
Published in Russian Journal of Bioorganic Chemistry
AbstractExtremophilic microorganisms, which are capable of functioning normally at extremely high or low temperatures, pressure, and in other environmental conditions, have been in the focus of microbiologists’ attention for several decades due to the biotechnological potential of enzymes inherent in extremophiles. These enzymes (also called extrem...
Published in Theoretical Foundations of Chemical Engineering
AbstractA computational scheme has been presented for estimating the technological characteristics of the continuous fermentation of lactic acid at a given concentration of the component that produces the main substrate. The computational scheme includes a preliminary analysis, the principal analysis, and a numerical example of the implementation o...