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Evaluation of silk-based bioink during pre and post 3D bioprinting: A review.

Published in Journal of biomedical materials research. Part B, Applied biomaterials

During past few decades, the demand for the replacement of damaged organs is increasing consistently. This is due to the advancement in tissue engineering, which opens the possibility of regeneration of damaged organs or tissues into functional parts with the help of 3D bioprinting. Bioprinting technology presents an excellent potential to develop ...

Three-Dimensional Bioprinting of Articular Cartilage: A Systematic Review.

Published in Cartilage

Treatment of chondral injury is clinically challenging. Available chondral repair/regeneration techniques have significant shortcomings. A viable and durable tissue engineering strategy for articular cartilage repair remains an unmet need. Our objective was to systematically evaluate the published data on bioprinted articular cartilage with regards...

Patient-Specific Bone Particles Bioprinting for Bone Tissue Engineering

Although bioinks with both high printability and shape fidelity while maintaining high cell viability are developed, the biofunctionality of the resulting bioprinted construct is often overlooked. To address this, a methacrylated gelatin (GelMA)-based bioink biofunctionalized with bone particles (BPs) is developed as a personalized treatment strate...

Monitoring Endothelin-A Receptor Expression during the Progression of Atherosclerosis.

Published in Biomedicines

Cardiovascular disease remains the most frequent cause of death worldwide. Atherosclerosis, an underlying cause of cardiovascular disease, is an inflammatory disorder associated with endothelial dysfunction. The endothelin system plays a crucial role in the pathogenesis of endothelial dysfunction and is involved in the development of atherosclerosi...

3D Bioprinting of Neural Tissues.

Published in Advanced healthcare materials

The human nervous system is a remarkably complex physiological network that is inherently challenging to study because of obstacles to acquiring primary samples. Animal models offer powerful alternatives to study nervous system development, diseases, and regenerative processes, however, they are unable to address some species-specific features of t...

Hydrogel-based 3D bioprints repair rat small intestine injuries and integrate into native intestinal tissue.

Published in Journal of tissue engineering and regenerative medicine

3D Printing has become a mainstay of industry, with several applications in the medical field. One area that could benefit from 3D printing is intestinal failure due to injury or genetic malformations. We bioprinted cylindrical tubes from rat vascular cells that were sized to form biopatches. 2 mm enterotomies were made in the small intestine of ma...

The Influence of Printing Parameters and Cell Density on Bioink Printing Outcomes.

Published in Tissue engineering. Part A

Bioink printability persists as a limiting factor toward many bioprinting applications. Printing parameter selection is largely user-dependent, and the effect of cell density on printability has not been thoroughly investigated. Recently, methods have been developed to give greater insight into printing outcomes. This study aims to further advance ...

Safety Considerations in 3D Bioprinting Using Mesenchymal Stromal Cells

Published in Frontiers in Bioengineering and Biotechnology

Three-dimensional (3D) bioprinting has demonstrated great potential for the fabrication of biomimetic human tissues and complex graft materials. This technology utilizes bioinks composed of cellular elements placed within a biomaterial. Mesenchymal stromal cells (MSCs) are an attractive option for cell selection in 3D bioprinting. MSCs can be isola...