Frizziero, Melissa Kilgour, Elaine Simpson, Kathryn L. Rothwell, Dominic G. Moore, David A. Frese, Kristopher K. Galvin, Melanie Lamarca, Angela Hubner, Richard A. Valle, Juan W.
...
Published in
Clinical cancer research : an official journal of the American Association for Cancer Research
Poorly-Differentiated NeuroEndocrine Carcinomas (PD-NECs) are rare cancers garnering interest as they become more commonly encountered in clinic. This is due to improved diagnostic methods and the increasingly observed phenomenon of ‘NE lineage plasticity’, whereby non-NeuroEndocrine (non-NE) epithelial cancers transition to aggressive NE phenotype...
Pries-Heje, Mia Marie Hasselbalch, Rasmus Bo Wiingaard, Christoffer Fosbøl, Emil Loldrup Glenthøj, Andreas Birkedal Ihlemann, Nikolaj Gill, Sabine Ute Alice Christiansen, Ulrik Elming, Hanne Bruun, Niels Eske
...
Published in
Heart (British Cardiac Society)
To assess the prevalence and severity of anaemia in patients with left-sided infective endocarditis (IE) and association with mortality. In the Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis trial, 400 patients with IE were randomised to conventional or partial oral antibiotic treatment after stabilisation of infection, showin...
Porta, Miquel Gasull, Magda Pumarega, José Kiviranta, Hannu Rantakokko, Panu Raaschou-Nielsen, Ole Bergdahl, Ingvar A Sandanger, Torkjel Manning Agudo, Antoni Rylander, Charlotta
...
Published in
International journal of epidemiology
Findings and limitations of previous studies on persistent organic pollutants (POPs) and pancreatic cancer risk support conducting further research in prospective cohorts. We conducted a prospective case-control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Participants were 513 pancreatic cance...
Janssens, Eline Mol, Zoë Vandermeersch, Lore Lagniau, Sabrina Vermaelen, Karim Y. van Meerbeeck, Jan P. Walgraeve, Christophe Marcq, Elly Lamote, Kevin
Published in
Frontiers in Oncology
Introduction Malignant pleural mesothelioma (MPM) is a lethal cancer for which early-stage diagnosis remains a major challenge. Volatile organic compounds (VOCs) in breath proved to be potential biomarkers for MPM diagnosis, but translational studies are needed to elucidate which VOCs originate from the tumor itself and thus are specifically relate...
Tosevska, Anela Morselli, Marco Basak, Saroj K. Avila, Luis Mehta, Parag Wang, Marilene B. Srivatsan, Eri S. Pellegrini, Matteo
Published in
Frontiers in Oncology
Liquid biopsies are gaining more traction as non-invasive tools for the diagnosis and monitoring of cancer. In a new paradigm of cancer treatment, a synergistic botanical drug combination (APG-157) consisting of multiple molecules, is emerging as a new class of cancer therapeutics, targeting multiple pathways and providing a durable clinical respon...
Maciejczyk, Mateusz Nesterowicz, Miłosz Zalewska, Anna Biedrzycki, Grzegorz Gerreth, Piotr Hojan, Katarzyna Gerreth, Karolina
Published in
Frontiers in Immunology
Stroke is one of the most common cerebrovascular diseases. Despite significant progress in understanding stroke pathogenesis, cases are still increasing. Thus, laboratory biomarkers of stroke are sought to allow rapid and non-invasive diagnostics. Ischemia-reperfusion injury is an inflammatory process with characteristic cellular changes leading to...
Ondigo, Bartholomew N. Hamilton, Rachael E. Magomere, Edwin O. Onkanga, Isaac O. Mwinzi, Pauline N. Odiere, Maurice R. Ganley-Leal, Lisa
Published in
Frontiers in Immunology
Introduction Current diagnostic tools for schistosomiasis are limited, and new tests are necessary to enhance disease diagnosis and surveillance. Identification of novel disease-specific biomarkers may facilitate the development of such tests. We evaluated a panel of biomarkers used in sepsis and parasitic diseases for their potential suitability i...
Zanella, Isabella Blasco, Hélène Filosto, Massimiliano Biasiotto, Giorgio
Published in
Frontiers in Neuroscience
Lerkvaleekul, Butsabong Veldkamp, Saskia R van der Wal, M Marlot Schatorjé, Ellen J H Kamphuis, Sylvia S M van den Berg, J Merlijn Hissink Muller, Petra C E Armbrust, Wineke Vastert, Sebastiaan J Wienke, Judith
...
Published in
Rheumatology (Oxford, England)
JDM is a rare chronic immune-mediated inflammatory disease with a predominant role for type I IFN responses. We aimed to determine the potential of Siglec-1 expression on monocytes as a novel IFN-inducible biomarker for disease activity monitoring and prediction of treatment response in patients with JDM. Siglec-1 was measured by flow cytometry on ...
Du, Xinhao Li, Qing Tang, Zhenzhen Yan, Li Zhang, Ling Zheng, Qiao Zeng, Xianghao Chen, Guimei Yue, Huawen Li, Jun
...
Published in
Frontiers in Physiology
Objective: The gut microbiota and its metabolites are important for host physiological homeostasis, while dysbiosis is related to diseases including the development of cancers such as colorectal cancer (CRC). In this study, we characterized the relationship of an altered gut microbiome with the fecal metabolome in CRC patients in comparison with vo...
