Shimura, Tadanobu Toden, Shusuke Kandimalla, Raju Toiyama, Yuji Okugawa, Yoshinaga Kanda, Mitsuro Baba, Hideo Kodera, Yasuhiro Kusunoki, Masato Goel, Ajay
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Published in
Annals of surgery
This study aimed to conduct a genomewide transcriptomic profiling to develop a microRNA (miRNA)-based signature for the identification of peritoneal metastasis (PM) in patients with gastric cancer (GC). Even though PM in patients with GC has long been recognized to associate with poor prognosis, currently there is lack of availability of molecular ...
Raess, Natalie Schuetz, Philipp Cesana-Nigro, Nicole Winzeler, Bettina Urwyler, Sandrine A Schaedelin, Sabine Rodondi, Nicolas Blum, Manuel R Briel, Matthias Mueller, Beat
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Published in
Journal of clinical pharmacology
Glucocorticoids are frequently prescribed in inflammatory diseases and have recently experienced a boom in the treatment of COVID-19. Small studies have shown an effect of glucocorticoids on inflammatory marker levels, but definitive proof is lacking. We investigated the influence of prednisone on inflammatory biomarkers in a previous multicenter, ...
Carrero, Ana Berenguer, Juan Hontañón, Víctor Guardiola, Josep M Navarro, Jordi von Wichmann, Miguel A Téllez, María J Quereda, Carmen Santos, Ignacio Sanz, José
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Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Little is known about the effects of eradication of hepatitis C virus (HCV) on bone mineral density (BMD) and biomarkers of bone remodeling in human immunodeficiency virus (HIV)/HCV-coinfected patients. We prospectively assessed standardized BMD (sBMD) at the lumbar spine and femoral neck, World Health Organization BMD categories at both sites, and...
Vidak, Marko Jovchevska, Ivana Šamec, Neja Zottel, Alja Liović, Mirjana Rozman, Damjana Džeroski, Sašo Juvan, Peter Komel, Radovan
Glioblastoma (GB) is the most aggressive brain malignancy. Although some potential glioblastoma biomarkers have already been identified, there is a lack of cell membrane-bound biomarkers capable of distinguishing brain tissue from glioblastoma and/or glioblastoma stem cells (GSC), which are responsible for the rapid post-operative tumor reoccurrenc...
Gomez Hernandez, M Paula Starman, Emily E Davis, Andrew B Withanage, Miyuraj Harishchandra Hikkadu... Zeng, Erliang Lieberman, Scott M Brogden, Kim A Lanzel, Emily A
Published in
Rheumatology (Oxford, England)
SS is an autoimmune disease most commonly diagnosed in adults but can occur in children. Our objective was to assess the presence of chemokines, cytokines and biomarkers (CCBMs) in saliva from these children that were associated with lymphocyte and mononuclear cell functions. Saliva was collected from 11 children diagnosed with SS prior to age 18 y...
Matsuda, Shogo Kotani, Takuya Kuwabara, Hiroko Suzuka, Takayasu Kiboshi, Takao Fukui, Keisuke Ishida, Takaaki Fujiki, Youhei Shiba, Hideyuki Hata, Kenichiro
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Published in
Rheumatology (Oxford, England)
Microscopic polyangiitis (MPA) is often complicated by interstitial lung disease (ILD); however, biomarkers that can be used to diagnose and predict the progression of MPA-ILD have not been identified. In this study, we evaluated various serum biomarkers in MPA-ILD to assess their diagnostic and predictive performance. We enrolled 49 patients with ...
Fajardo, Rebeca Guillén Fariña, Fátima Otero Rey, Alejandro Mosquera Rego-Pérez, Ignacio Blanco, Francisco J García, José Luis Fernández
Published in
The Journal of rheumatology
To evaluate the evolution of telomere length from peripheral blood leukocytes (PBLs) in subjects from the Osteoarthritis Initiative (OAI) cohort in relation to the incidence of osteoarthritis (OA), and to explore its possible interactive influence with the mitochondrial DNA (mtDNA) haplogroup. Dynamics of telomere sequence loss were quantified in P...
Kessel, Christoph Vollenberg, Richard Masjosthusmann, Katja Hinze, Claas Wittkowski, Helmut Debaugnies, France Nagant, Carole Corazza, Francis Vély, Frédéric Kaplanski, Gilles
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Published in
Arthritis & rheumatology (Hoboken, N.J.)
Infection with the novel coronavirus SARS-CoV-2 triggers severe illness with high mortality in a subgroup of patients. Such a critical course of COVID-19 is thought to be associated with the development of cytokine storm, a condition seen in macrophage activation syndrome (MAS) and secondary hemophagocytic lymphohistiocytosis (HLH). However, specif...
Pasqualetti, Francesco Sainato, Aldo Morganti, Riccardo Laliscia, Concetta Vasile, Enrico Gonnelli, Alessandra Montrone, Sabrina Gadducci, Giovanni Giannini, Noemi Coccia, Natalina
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Published in
Anticancer research
Pancreatic adenocarcinoma is a life-threatening disease with a rising frequency and the fourth leading cause of cancer death. This review aimed to assess the impact of postoperative radiotherapy through a meta-analysis of prospective randomized studies. Six studies met the inclusion criteria and were analyzed to calculate the cumulative risk of dea...
Stergar, Jošt
The goal of the work presented in this thesis was to compare spectroscopic properties of tissues on the macro scale with their underlying microscopic structural properties. Three main objectives that dictate the organization of this thesis were identified. (I) To develop and characterize two hyperspectral imaging systems that can im- age on two dif...
