Uvod: specifična imunoterapija je edini način zdravljenja pacientov, ki so imeli težko anafilaksijo po piku kožekrilca. Med imunoterapijo lahko pride do težkih zapletov, zato jo je pri nekaterih pacientih treba prekiniti. Namen dela: ugotoviti dejavnike, ki napovedujejo težke zaplete med imunoterapijo s strupi kožekrilcev in ugotoviti, ali dodatno ...
Published in Frontiers in Pediatrics
Objectives: To determine the efficacy of serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in predicting critical pulmonary stenosis (CPS) in neonates. Methods: All neonates with pulmonary stenosis (PS) admitted to the neonatal intensive care unit of Xinhua Hospital from October 2014 to December 2020 were retrospectively reviewed. ...
Published in Inflammatory bowel diseases
Inflammatory bowel disease (IBD) is associated with alterations of the innate and adaptive immune systems. Monocytes respond to inflammation and infection, yet the relationship between monocytosis and IBD severity is not fully understood. We aimed to characterize the prevalence of monocytosis in IBD and the association between monocytosis and disea...
Published in Frontiers in Immunology
Background Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a systemic autoimmune disease that generally induces the progression of rapidly progressive glomerulonephritis (GN). The purpose of this study was to identify key biomarkers and immune-related pathways involved in the progression of ANCA-associated GN (ANCA-GN) and...
Published in Frontiers in Pharmacology
Published in Frontiers in Pediatrics
Background: Kawasaki disease (KD) is the leading cause of acquired heart disease in children. However, distinguishing KD from febrile infections early in the disease course remains difficult. Our goal was to estimate the immune cell composition in KD patients and febrile controls (FC), and to develop a tool for KD diagnosis. Methods: We used a mach...
Published in Frontiers in Genetics
Background: SPP1, secreted phosphoprotein 1, is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family. Previous studies have proven SPP1 overexpressed in a variety of cancers and can be identified as a prognostic factor, while no study has explored the function and carcinogenic mechanism of SPP1 in cervical cancer. Me...
Published in International journal of environmental research and public health
Lead poisoning is often considered a traditional disease; however, the specific mechanism of toxicity remains unclear. The study of Pb-induced alterations in cellular metabolic pathways is important to understand the biological response and disorders associated with environmental exposure to lead. Metabolomics studies have recently been paid consid...
Published in Frontiers in Genetics
Background: Serpin peptidase inhibitor clade H, member 1 (SERPINH1) is a gene encoding a member of the serpin superfamily of serine proteinase inhibitors. The upregulated of SERPINH1 was associated with poor prognosis in breast cancer, stomach adenocarcinoma, and esophageal carcinoma. However, the role of SERPINH1 in pan-cancer is largely unexplore...
Published in International journal of environmental research and public health
Rare earth elements (REEs) are emerging contaminants. Previous studies reported the association between REEs and active smoking, but little is known about the effects of passive smoking on this condition. In China, female passive smoking is widespread, particularly in rural areas. This study aimed to estimate the relationship between REEs accumulat...
