Kalkan, Özlem Kantamneni, Sravya Brings, Lea Han, Huijong Bean, Richard Mancuso, Adrian P. Koua, Faisal H. M.
Published in
Frontiers in Chemistry
The Dictyostelium discoideum dye-decolorizing peroxidase (DdDyP) is a newly discovered peroxidase, which belongs to a unique class of heme peroxidase family that lacks homology to the known members of plant peroxidase superfamily. DdDyP catalyzes the H2O2-dependent oxidation of a wide-spectrum of substrates ranging from polycyclic dyes to lignin bi...
Cui, Jiandong Ocsoy, Ismail Mahmoud, Mohamed Abdelraof Du, Yingjie
Published in
Frontiers in Bioengineering and Biotechnology
Gebauer, Jan Pietruszka, Jörg Classen, Thomas
Published in
Frontiers in Catalysis
Introduction: The antimicrobial pyrrolnitrin from Pseudomonas strains is formed in four steps from tryptophan and comprises two flavin-dependent halogenases. Both PrnC and PrnA can carry out regioselective chlorination and bromination and are carrier protein-independent. Whilst the tryptophan halogenase PrnA has been studied in detail in the past, ...
Qi, Xianghui Cui, Jiandong Mofijur, M. Zabed, Hossain M.
Published in
Frontiers in Bioengineering and Biotechnology
Jain, Kunal R. Desai, Chirayu van Hullebusch, Eric D. Madamwar, Datta
Published in
Frontiers in Bioengineering and Biotechnology
Ho, Y. T. Candace Izoré, Thierry Kaczmarski, Joe A. Marschall, Edward Ratnayake, Minuri S. Tailhades, Julien Steer, David L. Schittenhelm, Ralf B. Tosin, Manuela Jackson, Colin J.
...
Published in
Frontiers in Catalysis
In nonribosomal peptide synthesis, condensation (C) domains are key catalytic domains that most commonly link carrier protein bound substrates to form peptides or depsipeptides. While adenylation domains have been well characterized due to their role in the selection of monomers and hence as gate keepers in nonribosomal peptide biosynthesis, C-doma...
Ralbovsky, Nicole M Smith, Joseph P
Published in
Pharmaceutical research
Enzyme immobilization is a beneficial component involved in biocatalytic strategies. Understanding and evaluating the enzyme immobilization system plays an important role in the successful development and implementation of the biocatalysis route. Ensuring the implementation of a successful enzyme immobilization process is vital for realizing a high...
Ingold, Zoe Grogan, Gideon Lichman, Benjamin R.
Published in
Frontiers in Catalysis
Deoxypodophyllotoxin synthase (DPS) is a 2-oxoglutarate (2-OG) dependent non-heme iron (II) dioxygenase that catalyzes the stereoselective ring-closing carbon-carbon bond formation of deoxypodophyllotoxin from the aryllignan (−)-yatein. Deoxypodophyllotoxin is a precursor of topoisomerase II inhibitors, which are on the World Health Organization’s ...
Terholsen, Henrik Meyer, Jule R H Zhang, Zhenlei Deuss, Peter J Bornscheuer, Uwe T
Published in
ChemSusChem
Combining solid acid catalysts with enzyme reactions in aqueous environments is challenging because either very acidic conditions inactivate the enzymes, or the solid acid catalyst is neutralized. In this study, Amberlyst-15 encapsulated in polydimethylsiloxane (Amb-15@PDMS) is used to deprotect the lignin depolymerization product G-C2 dioxolane ph...
Wang, Zi-Kai Gong, Jin-Song Feng, Dan-Ting Su, Chang Li, Hui Rao, Zhi-Ming Lu, Zhen-Ming Shi, Jin-Song Xu, Zheng-Hong
Published in
Applied and Environmental Microbiology
Nitrilase can catalyze nitrile compounds to generate corresponding carboxylic acids. Nitrilases as promiscuous enzymes can catalyze a variety of nitrile substrates, such as aliphatic nitriles, aromatic nitriles, etc. However, researchers tend to prefer enzymes with high substrate specificity and high catalytic efficiency. In this study, we develope...
