Byrd, Kathy K Hou, John G Bush, Tim Hazen, Ron Kirkham, Heather Delpino, Ambrose Weidle, Paul J Shankle, Michael D Camp, Nasima M Suzuki, Sumihiro
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Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Human immunodeficiency virus (HIV) viral suppression (VS) decreases morbidity, mortality, and transmission risk. The Patient-centered HIV Care Model integrated community-based pharmacists with HIV medical providers and required them to share patient clinical information, identify therapy-related problems, and develop therapy-related action plans.Pr...
Xie, Xiwei Zhang, Caili Weng, Yunxuan Diao, Xiaoqian Song, Xinyu
Published in
Materials (Basel, Switzerland)
Due to the hydrophobic nature of poly (butylene terephthalate) (PBAT), and the hydrophilic nature of bamboo flour (BF), a BF/PBAT (50/50) blend shows low mechanical properties, and especially shows poor impact strength. In order to increase the interfacial adhesion between BF and PBAT, diisocyanate was used as a reactive compatibilizer to modify ba...
Govednik, Tea
Drastičen napredek protiretrovirusnega zdravljenja je okužbo z virusom HIV pretvoril v obvladljivo kronično stanje. Kljub temu je uspešnost zdravljenja močno odvisna od razvoja z odpornostjo povezanih mutacij, ki v primeru prenosa med nezdravljenimi osebami, predstavljajo primarno odpornost virusa (angl. transmitted drug resistance, TDR). Glede na ...
Cohen, Myron S. Gamble, Theresa McCauley, Marybeth
The HIV Prevention Trials Network 052 study (HPTN 052) was a clinical trial designed to determine whether early treatment for HIV infection prevented transmission of the virus in couples where one partner was infected with HIV and the other was not, referred to as HIV serodiscordant or serodifferent couples. The study enrolled 1,763 couples at 13 s...
Myer, Landon Redd, Andrew D Mukonda, Elton Lynch, Briana A Phillips, Tamsin K Eisenberg, Anna Hsiao, Nei-Yuan Capoferri, Adam Zerbe, Alison Clarke, William
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Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Elevated viral load (VL) early after antiretroviral therapy (ART) initiation appears frequently in pregnant and postpartum women living with human immunodeficiency virus; however the relative contributions of pre-ART drug resistance mutations (DRMs) vs nonadherence in the etiology of elevated VL are unknown. Within a cohort of women initiating ART ...
gesesew, hailay ward, paul woldemichael, kifle mwanri, lillian
Ethiopia&rsquo / s performance toward the UNAIDS 90-90-90 targets is low. The present study explored interventions to improve delayed HIV care presentation (first 90), poor retention (second 90) and clinical and immunological failure (third 90). We employed a qualitative approach using in-depth interviews with 10 HIV patients, nine health workers, ...
Mehraj, Vikram Ramendra, Rayoun Isnard, Stéphane Dupuy, Franck P Ponte, Rosalie Chen, Jun Kema, Ido Jenabian, Mohammad-Ali Costinuik, Cecilia T Lebouché, Bertrand
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Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Microbial translocation from the gut to systemic circulation contributes to immune activation during human immunodeficiency virus (HIV) infection and is usually assessed by measuring plasma levels of bacterial lipopolysaccharide (LPS). Fungal colonization in the gut increases during HIV-infection and people living with HIV (PLWH) have increased pla...
Jácome-Santos, Humberto Amanajás, Thalita de Almeida Gomes, Samara Tatielle Monteiro Machado, Luiz Fernando Almeida Pereira Neto, Armando Rodrigues Lopes Alves Junior, Sérgio de Melo Pinheiro, João de Jesus Viana Alves, Bruno Pereira Amoras-Alves, Ana Cláudia Braga
Published in
Quintessence international (Berlin, Germany : 1985)
This study aimed to investigate the Epstein-Barr virus (EBV) prevalence and viral load in subgingival sites of human immunodeficiency virus type 1 (HIV-1) positive (HIV+) individuals, correlating subgingival EBV load to the clinical periodontal condition, HIV systemic load, EBV systemic load, and use of antiretroviral therapy (ART). Ninety individu...
Sanchez, Rosa I Yee, Ka Lai Fan, Li Cislak, Dawn Martell, Maureen Jordan, Heather R Iwamoto, Marian Khalilieh, Sauzanne
Published in
Clinical pharmacology in drug development
Doravirine is a novel nonnucleoside reverse transcriptase inhibitor for the treatment of human immunodeficiency virus type-1 (HIV-1) infection. In vitro and clinical data suggest that doravirine is unlikely to cause significant drug-drug interactions via major drug-metabolizing enzymes or transporters. As a common HIV-1 infection comorbidity, type ...
Melo, Rita Lemos, Agostinho Preto, António J Bueschbell, Beatriz Matos-Filipe, Pedro Barreto, Carlos Almeida, José G Silva, Rúben D M Correia, João D G Moreira, Irina S
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Published in
Current medicinal chemistry
Paediatric Acquired ImmunoDeficiency Syndrome (AIDS) is a life-threatening and infectious disease in which the Human Immunodeficiency Virus (HIV) is mainly transmitted through Mother-To- Child Transmission (MTCT) during pregnancy, labour and delivery, or breastfeeding. This review provides an overview of the distinct therapeutic alternatives to abo...
