0.1) between PLHIV and HC. Plasma levels of several essential amino acids except for histidine, branched-chain amino acids, and aromatic amino acids (phenylalanine, tyrosine, tryptophan) were significantly lower in PLHIV compared to HC. Machine-learning prediction of metabolite changes indicated a higher risk of inflammatory and neurological diseas...
Previous qualitative studies about antiretroviral therapy (ART) adherence have largely focused on patient experiences. Less is known about the perspective of health care providers-particularly in low-income countries-who serve as gatekeepers and influencers of patients' HIV care experiences. This study explored patients' and providers' perceptions ...
20%) of DRMs. Our method can be incorporated into large-scale surveillance of HIV-1 DRM.
Published in Trials
BackgroundThere is a need for evaluating community-based antiretroviral therapy (ART) delivery models to improve overall performance of HIV programs, specifically in populations that may have difficulties to access continuous care. This cluster-randomized clinical trial aims to evaluate the effectiveness of a multicomponent differentiated ART deliv...
Antiretroviral therapy (ART) has significantly improved life expectancy of infected subjects, generating a new epidemiological setting of people aging withHuman Immunodeficiency Virus (HIV). People living with HIV (PLWH), having longer life expectancy, now face several age-related conditions as well as side effects of long-term exposure of ART. Chr...
Background: Antiretroviral treatment (ART) has been shown to have a beneficial effect on the weight evolution but its effect on height remains unclear. We described patterns of height evolution and identified predictors of catch-up growth in HIV-infected children on ART.Methods: To describe the height evolution from birth to adulthood, we developed...
= 0.48, 95% CI: 0.05, 0.92). Interaction between VD and IPA exposure for SEA outcomes among HEU and PHIV children warrants further investigation. The vitamin-D associated SEA improvement among HUU and HEU without IPA exposure suggests vitamin-D supplementation may remediate behavioral and adaptive deficits in this groups.
Published in MMW - Fortschritte der Medizin
Im vergangenen Jahr wurde die Leitlinie zur HIV-Postexpositionsprophylaxe überarbeitet. Sie gibt konkrete Empfehlungen, was nach Verdacht auf eine HIV-Übertragung zu tun ist und wann und wie antiretrovirale Medikamente verabreicht werden sollen.
Published in MMW - Fortschritte der Medizin
Kondomloser Sex mit einem behandelten HIV-positiven Partner ist deutlich sicherer als mit einer Person mit unbekanntem HIV-Status. Von dieser Tatsache profitieren sowohl hetero- als auch homosexuelle Paare. Trotzdem werden viele HIV-Infizierte weiterhin diskriminiert.
OBJECTIVE:To determine whether changing antiretroviral therapy (ART) during pregnancy because of concern about fetal risks led to poorer virological outcomes.METHODS:All pregnancies in women with HIV-1 infection enrolled in the national multicenter prospective French Perinatal cohort at 14 week gestation or more were included between January 2005 a...
