Suliburska, Joanna Pankiewicz, Jakub Sajnóg, Adam Paczkowska, Magdalena Nowakowska, Beata Bakinowska, Ewa Barałkiewicz, Danuta Kocyłowski, Rafał
Published in
Diagnostics (Basel, Switzerland)
The present study aimed to investigate the relationship between the concentrations of essential and toxic elements present in the amniotic fluid (AF) and fetal chromosomal abnormalities in pregnant women. A total of 156 pregnant white Polish women aged between 20 and 43 years and screened to detect high risk for chromosomal defects in the first tri...
Wu, Jing Feng, Li Zhang, Hongwei Guo, Li Pérez-Escamilla, Rafael Hu, Yifei
Published in
Frontiers in Public Health
Background Previous studies have found that the rates of cesarean preference were much lower than the actual rates of cesarean births in China. We aimed to observe this inconsistency between preferred and actual modes of delivery and the factors associated with the inconsistency. Methods We conducted a prospective cohort study at the maternity hosp...
Zhang, Longmiao Tan, Chengquan Xin, Zhongquan Huang, Shuangbo Ma, Junwu Zhang, Meiyu Shu, Gang Luo, Hefeng Deng, Baichuan Jiang, Qingyan
...
Published in
Frontiers in Nutrition
Pregnancy is a complex and dynamic process, the physiological and metabolite changes of the mother are affected by different pregnancy stages, but little information is available about their changes and potential mechanisms during pregnancy, especially in blood and amniotic fluid. Here, the maternal metabolism rules at different pregnancy stages we...
Winters, Andrew D. Romero, Roberto Greenberg, Jonathan M. Galaz, Jose Shaffer, Zachary D. Garcia-Flores, Valeria Kracht, David J. Gomez-Lopez, Nardhy Theis, Kevin R.
Published in
Frontiers in Immunology
The existence of an amniotic fluid microbiota (i.e., a viable microbial community) in mammals is controversial. Its existence would require a fundamental reconsideration of fetal in utero exposure to and colonization by microorganisms and the role of intra-amniotic microorganisms in fetal immune development as well as in pregnancy outcomes. In this...
Sasso, Elizabeth B Thornton, Matthew E Chmait, Ramen H Ouzounian, Joseph G Grubbs, Brendan H
Published in
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
In utero neurologic injury in myelomeningocele (MMC) occurs via a two-hit process: failed neural tube closure followed by neurodegeneration in utero. Meconium in the amniotic fluid contains pancreatic digestive enzymes and is neurotoxic in rat models of MMC. The objectives of this study were to demonstrate the neurotoxicity of α-amylase and to comp...
Neamtu, Radu Ionut Craina, Marius Dahma, George Popescu, Alin Viorel Erimescu, Adelina Geanina Citu, Ioana Dobrescu, Amadeus Horhat, Florin George Vulcanescu, Dan Dumitru Gorun, Florin
...
Published in
Experimental and Therapeutic Medicine
The growth and development of the fetus is a complex phenomenon that can be influenced by several variables. High quantities of heavy metal ions in the amniotic fluid have been linked to poor health, especially in industrial, polluted and poor areas. The aim of the present study was to assess the differences in the concentration of these ions betwe...
Schwenkel, George Romero, Roberto Slutsky, Rebecca Motomura, Kenichiro Hsu, Chaur-Dong Gomez-Lopez, Nardhy
Published in
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Preterm labor and birth are strongly associated with sterile intra-amniotic inflammation, a clinical condition that is proposed to be initiated by danger signals, or alarmins. The aim of this study was to investigate whether the intra-amniotic administration of the alarmin heat shock protein 70 (HSP70) induces preterm labor/birth and adverse neonat...
Becktell, Liliya Matuska, Andrea M Hon, Stephanie Delco, Michelle L Cole, Brian J Begum, Laila Zhang, Sheng Fortier, Lisa A
Published in
Cartilage
Amnion products are used in various musculoskeletal surgeries and as injections for joint pain with conflicting reports of cell viability and protein contents. The objective of this study was to determine the full proteome and examine cell viability in 9 commercial amnion products using an unbiased bottom-up shotgun proteomics approach and confocal...
Jin, Xiao-Xiao Xu, Yan-Fei Ying, Xiang Qian, Ye-Qing Jin, Peng-Zhen Dong, Min-Yue
Published in
International Journal of Women's Health
Objective This paper analyzes the clinical significance of noninvasive prenatal testing (NIPT) for fetal chromosome aneuploidy in the screening of in vitro fertilization–embryo transfer (IVF) pregnancies. Methods The study subjects consisted of 3163 IVF-pregnant women who underwent NIPT at the Women’s Hospital, School of Medicine, Zhejiang Universi...
Hughes, Dawn Simmons, Brianna Magann, Everett Wendel, Michael Whittington, Julie R Ounpraseuth, Songthip
Published in
International Journal of Women's Health
Objective Two different techniques are described in the literature for measuring amniotic fluid pockets to estimate amniotic fluid volume. This study was undertaken to determine if ultrasound estimates using amniotic fluid index (AFI) and single deepest pocket (SDP) techniques should be measured perpendicular to floor vs perpendicular to uterine co...