and (iii) genomic and epigenetic changes, and the evolutionary and selective processes occurring during culture expansion, associated with production of iPSC-therapeutics. In addition, (iv) methods for the practical culture-at-scale and standardization required for routine clinical use are considered. Finally, (v) the potential of iPSC in the treat...
0.01). Each risk factor was associated with a two-fold increase in the odds of severe diarrhea, and this was consistent between individuals commenced on 40 mg or 50 mg afatinib. A simple risk score based on the count of these risk factors identifies individuals at lowest and highest risk (C-statistic of 0.65). Risk of severe diarrhea for individual...
however, whether children are using dietary supplements appropriately remains unclear. This study aimed to determine dietary supplement use among children. In August 2017, a nationwide internet preliminary survey of 265,629 mothers aged from 25 to 59 years old was undertaken. Of these, 19,041 mothers of children attending either elementary school, ...
Background: We evaluated the burden of adverse events (AEs) caused by beta-blocker use after acute myocardial infarction (AMI) in frail, older nursing home (NH) residents. Methods: This retrospective cohort study used national Medicare claims linked to Minimum Data Set assessments. The study population was individuals aged > /=65 years who resided ...
Background: We evaluated the burden of adverse events (AEs) caused by beta-blocker use after acute myocardial infarction (AMI) in frail, older nursing home (NH) residents. Methods: This retrospective cohort study used national Medicare claims linked to Minimum Data Set assessments. The study population was individuals aged > /=65 years who resided ...
Background: We evaluated the burden of adverse events (AEs) caused by beta-blocker use after acute myocardial infarction (AMI) in frail, older nursing home (NH) residents. Methods: This retrospective cohort study used national Medicare claims linked to Minimum Data Set assessments. The study population was individuals aged > /=65 years who resided ...
1 year) showed significantly higher odds of hospitalization. Conclusions: The Brazilian AEFI registry is useful to compare the magnitude and certain characteristics of adverse events associated with mandated pediatric vaccines.
Aims:5-FU is used as the main backbone of chemotherapy regimens for patients with colorectal and other gastrointestinal cancers. Despite development of new strategies that allowed enhancing clinical effectiveness and tolerability of 5-FU, 10-30% of patients treated with 5-FU-based regimens experience severe treatment-related toxicity. In our study,...
Aims:5-FU is used as the main backbone of chemotherapy regimens for patients with colorectal and other gastrointestinal cancers. Despite development of new strategies that allowed enhancing clinical effectiveness and tolerability of 5-FU, 10-30% of patients treated with 5-FU-based regimens experience severe treatment-related toxicity. In our study,...
Aims:5-FU is used as the main backbone of chemotherapy regimens for patients with colorectal and other gastrointestinal cancers. Despite development of new strategies that allowed enhancing clinical effectiveness and tolerability of 5-FU, 10-30% of patients treated with 5-FU-based regimens experience severe treatment-related toxicity. In our study,...
