Dimitriadis, George D Maratou, Eirini Kountouri, Aikaterini Board, Mary Lambadiari, Vaia
Published in
Nutrients
Glucose levels in blood must be constantly maintained within a tight physiological range to sustain anabolism. Insulin regulates glucose homeostasis via its effects on glucose production from the liver and kidneys and glucose disposal in peripheral tissues (mainly skeletal muscle). Blood levels of glucose are regulated simultaneously by insulin-med...
Allahyari, Mostafa Rajaie, Athena Fallah, Hossein
Published in
Asian Biomedicine
Background Obesity and the inflammation associated with it, play a key role in the development of insulin resistance through the release of inflammatory cytokines and free fatty acids and the stimulation of toll-like receptors (TLR). Interleukin-1 receptor-associated kinase (IRAK), which mediates the activation of nuclear factor kappa-light-chain-e...
Mikhailov, Mikhail I Lopatukhina, Maria A Asadi Mobarhan, Fedor A Ilchenko, Lyudmila Yu Kozhanova, Tatyana V Isaeva, Olga V Karlsen, Anastasiya A Potemkin, Ilya A Kichatova, Vera S Saryglar, Anna A
...
Published in
Vaccines
Since August 2012, universal single-dose vaccination in children aged at least three years has been implemented in the Republic of Tuva, which was previously the region most affected by hepatitis A in Russia. The objective of this cross-sectional study was the assessment of the immunological and epidemiological effectiveness of vaccination program ...
Rajar, Teja
Sohail, Muhammad N Blomstedt, Cecilia K Gleadow, Roslyn M
Published in
Plants (Basel, Switzerland)
In plants, the production of secondary metabolites is considered to be at the expense of primary growth. Sorghum produces a cyanogenic glycoside (dhurrin) that is believed to act as its chemical defence. Studies have shown that acyanogenic plants are smaller in size compared to the wildtype. This study aimed to investigate whether the small plant s...
Martínez-Uña, Maite López-Mancheño, Yaiza Diéguez, Carlos Fernández-Rojo, Manuel A Novelle, Marta G
Published in
International journal of molecular sciences
Since its discovery twenty-five years ago, the fat-derived hormone leptin has provided a revolutionary framework for studying the physiological role of adipose tissue as an endocrine organ. Leptin exerts pleiotropic effects on many metabolic pathways and is tightly connected with the liver, the major player in systemic metabolism. As a consequence,...
Camino, Tamara Lago-Baameiro, Nerea Martis-Sueiro, Aurelio Couto, Iván Santos, Francisco Baltar, Javier Pardo, María
Published in
International journal of molecular sciences
The extracellular vesicles (EVs) have emerged as key players in metabolic disorders rising as an alternative way of paracrine/endocrine communication. In particular, in relation to adipose tissue (AT) secreted EVs, the current knowledge about its composition and function is still very limited. Nevertheless, those vesicles have been lately suggested...
Manganyi, Madira Coutlyne Ateba, Collins Njie
Published in
Microorganisms
Over the last century, endophytic fungi have gained tremendous attention due to their ability to produce novel bioactive compounds exhibiting varied biological properties and are, therefore, utilized for medicinal, pharmaceutical, and agricultural applications. Endophytic fungi reside within the plant tissues without showing any disease symptoms, t...
Carneros, David Medina-Gómez, Gema Giralt, Marta León-Camacho, Manuel Campbell, Mark Moreno-Aliaga, Maria J Villarroya, Francesc Bustos, Matilde
Published in
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
It is becoming clear that several human pathologies are caused by altered metabolic adaptations. During liver development, there are physiological changes, from the predominant utilization of glucose (fetal life) to the use of lipids (postnatal life). Fasting is another physiological stress that elicits well-known metabolic adjustments. We have rep...
Liu, Yingshan Jin, Jing Chen, Yanshan Chen, Chuna Chen, Zhenguo Xu, Lingling
Published in
Adipocyte
We explored potential biomarkers and molecular mechanisms regarding multiple benefits after bariatric surgery. Differentially expressed genes (DEGs) for subcutaneous adipose tissue (AT) after bariatric surgery were identified by analyzing two expression profiles from the GEO. Subsequently, enrichment analysis, GSEA, PPI network, and gene-microRNAs ...
