Payares-Herrera, Concepción Martínez-Muñoz, María E. Vallhonrat, Inés Lipperheide de Molina, Rosa Malo Torres, Manuel Pérez Trisan, Andrea de Diego, Isabel Salcedo Alonso, Rosalía Zafra, Rocío Donaire, Trinidad
...
Published in
Trials
Objectives1. To assess the efficacy of Mesenchymal Stromal Cells (MSC) versus a control arm as described in the primary endpoint.2. To evaluate the effects of MSC on the secondary efficacy endpoints.3. To evaluate the safety and tolerability profiles of MSC.4. To study soluble and cellular biomarkers that might be involved in the course of the dise...
Grassin-Delyle, Stanislas Roquencourt, Camille Moine, Pierre Saffroy, Gabriel Carn, Stanislas Heming, Nicholas Fleuriet, Jérôme Salvator, Hélène Naline, Emmanuel Couderc, Louis-Jean
...
BackgroundEarly diagnosis of coronavirus disease 2019 (COVID-19) is of the utmost importance but remains challenging. The objective of the current study was to characterize exhaled breath from mechanically ventilated adults with COVID-19.MethodsIn this prospective observational study, we used real-time, online, proton transfer reaction time-of-flig...
Weikhard, Jerca
Ozadje: Kljub stalnim napredkom pri podporni oskrbi bolnikov s sindromom akutne dihalne stiske je njihova umrljivost še vedno zelo visoka. Za to patologijo je značilna huda poškodba pljuč, ki jo karakterizira odpoved oksigenacije in hipoksemija, pljučni edem, ter nato odpoved več organskih sistemov. Najpogosteje je posledica virusnih ali bakterijsk...
Rafiullah, Mohamed Siddiqui, Khalid
Published in
Journal of comparative effectiveness research
Dexamethasone was shown to decrease the mortality in coronavirus disease-2019 (COVID-19) recently. Use of corticosteroids was harmful in other coronavirus infections previously. WHO recommended against routine use of corticosteroids in COVID-19. In view of these, we reviewed the evidence about the use of corticosteroids in virus-induced acute respi...
Li, Juan Xu, Mei-xia Dai, Zhong Xu, Tao
Published in
Current Medical Science
Acute respiratory distress syndrome (ARDS) is one of the most fatal diseases worldwide. Pulmonary fibrosis occurs early in ARDS, and its severity plays a crucial role in ARDS mortality rate. Some studies suggested that fibroproliferation is an essential mechanism in ARDS. Mitofusion2 (Mfn2) overexpression plays a role in inhibiting cell proliferati...
Xu, Shilin Guo, Caili
Published in
Sensors (Basel, Switzerland)
To satisfy the explosive growth of computation-intensive vehicular applications, we investigated the computation offloading problem in a cognitive vehicular networks (CVN). Specifically, in our scheme, the vehicular cloud computing (VCC)- and remote cloud computing (RCC)-enabled computation offloading were jointly considered. So far, extensive rese...
Wataganara, Tuangsit Ruangvutilert, Pornpimol Sunsaneevithayakul, Prasert Sutantawibul, Anuwat Chuchotirot, Monsak Phattanachindakun, Buraya Russameecharoen, Kusol
Published in
Journal of Perinatal Medicine
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)–associated infection (COVID-19) is affecting populations worldwide. This statement may serve as guidance for infection prevention and safe ultrasound practices during the COVID-19 pandemic. Ultrasound examination is a fundamental part of obstetric care, yet it is a potential vector for tr...
Riga, Maria Ilias, Aris Vontas, John Douris, Vassilis
Published in
Insects
Overexpression of the cytochrome P450 monooxygenase CYP392A16 has been previously associated with abamectin resistance using transcriptional analysis in the two-spotted spider mite Tetranychus urticae, an important pest species worldwide; however, this association has not been functionally validated in vivo despite the demonstrated ability of CYP39...
Madahar, Purnema Talmor, Daniel Beitler, Jeremy R
Published in
American journal of respiratory and critical care medicine
Declercq, Jozefien Bosteels, Cedric Van Damme, Karel De Leeuw, Elisabeth Maes, Bastiaan Vandecauter, Ans Vermeersch, Stefanie Delporte, Anja Demeyere, Bénédicte Vuylsteke, Marnik
...
Published in
Trials
ObjectivesZilucoplan (complement C5 inhibitor) has profound effects on inhibiting acute lung injury post COVID-19, and can promote lung repair mechanisms that lead to improvement in lung oxygenation parameters. The purpose of this study is to investigate the efficacy and safety of Zilucoplan in improving oxygenation and short- and long-term outcome...
