Omar, Shaheed Vally Louw, Gail Ismail, Farzana Liu, Xiaohong Ngcamu, Dumsani Gwala, Thabisile van der Meulen, Minty Joseph, Lavania
Published in
Journal of Clinical Microbiology
Drug-resistant tuberculosis (TB) poses a significant public health concern in South Africa due to its complexity in diagnosis, treatment, and management. This study assessed the diagnostic performance of the Xpert MTB/XDR test for detecting drug resistance in patients with TB by using archived sputum sediments. This study analyzed 322 samples colle...
Črnigoj, Dean
Abbasi, Ali Hajihashemi, Bahareh Shokri, Dariush
Published in
Postępy Higieny i Medycyny Doświadczalnej
Introduction In recent years, colistin-resistant Acinetobacter baumannii (A. baumannii) has been found all over the world. In this current study, the main purpose was to examine the occurrence of extensively drug resistant (XDR), resistance to colistin and characterization and mutations in pmrCAB genes among A. baumannii obtained from inpatients. M...
Barker, Kevin R. Rebick, Gabriel W. Fakharuddin, Ken MacDonald, Clayton Mulvey, Michael R. Mataseje, Laura F.
Published in
Microbiology Spectrum
The development of cefiderocol, a novel siderophore cephalosporin, has provided additional options to the treatment of extensively drug-resistant (XDR) Gram-negative bacteria. Resistance to cefiderocol is poorly understood and only recently described. Here, we describe a case of a patient with recent travel to India harboring three Escherichia coli...
Stoycheva, Krista Cristea, Veronica Ködmön, Csaba Rosales-Klintz, Senia Zenner, Dominik Vasiliu, Anca van der Werf, Marieke Lange, Christoph
Published in
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Approximately five million Ukrainians were displaced to the EU/EEA following the Russian invasion of Ukraine. While tuberculosis (TB) notification rates per 100,000 Ukrainians in the EU/EEA remained stable, the number of notified TB cases in Ukrainians increased almost fourfold (mean 2019-2021: 201; 2022: 780). In 2022, 71% cases were notified in t...
Chowdhury, Atish Roy Mukherjee, Debapriya Chatterjee, Ritika Chakravortty, Dipshikha
Published in
Molecular microbiology
Salmonella Typhi, the invasive serovar of S. enterica subspecies enterica, causes typhoid fever in healthy human hosts. The emergence of antibiotic-resistant strains has consistently challenged the successful treatment of typhoid fever with conventional antibiotics. Antimicrobial resistance (AMR) in Salmonella is acquired either by mutations in the...
Maitre, Thomas Baulard, Alain Aubry, Alexandra Veziris, Nicolas
Published in
Infectious diseases now
Antibiotic-resistant tuberculosis continues to be one of the major threats to global tuberculosis control. After a hiatus of over 40 years in antituberculosis drug development, the last decade has seen a resurgence of research, yielding a number of promising compounds in the tuberculosis drug pipeline, with some that are now game changers in the tr...
Nazim, Tasmin Kumar, Vipul Ahmed, Faraz Ehtesham, Nasreen Z. Hasnain, Seyed E. Sundar, Durai Grover, Sonam
Published in
Frontiers in Molecular Biosciences
Mycobacterium tuberculosis (M.tb) remains a formidable global health threat. The increasing drug resistance among M.tb clinical isolates is exacerbating the current tuberculosis (TB) burden. In this study we focused on identifying novel repurposed drugs that could be further investigated as potential anti-TB drugs. We utilized M.tb RNA methyltransf...
Tabassum, Tahani Hossain, Sakib Ercumen, Ayse Benjamin-Chung, Jade Abedin, Foysal Rahman, Mahbubur Jahan, Farjana Haque, Munima Mahmud, Zahid Hayat
Antimicrobial resistance (AMR) is a rising health concern worldwide. As an indicator organism, E. coli, specifically extended-spectrum β-lactamase (ESBL) producing E. coli, can be used to detect AMR in the environment and estimate the risk of transmitting resistance among humans, animals and the environment. This study focused on detecting cefotaxi...
Dawaiwala, Idris Awaghade, Snehal Kolhatkar, Pranjali Pawar, Sunita Barsode, Supriya
Published in
The international journal of lower extremity wounds
Foot infections are the most prevalent problem in persons with diabetes. The burden of multidrug resistant (MDR) microorganisms in diabetic foot infections (DFIs) is rising day by day. Given that, the present study aims to determine the variety of microorganisms isolated from the diabetic foot ulcers (DFUs), and their antibiotic sensitivity pattern...