Cruz, Ofelia Caloretti, Victoria Salvador, Hector Celis, Veronica Santa-Maria, Vicente Morales La Madrid, Andrés Suñol, Mariona Puerta, Patricia Muchart, Jordi Krauel, Lucas
...
Published in
Hereditary Cancer in Clinical Practice
BackgroundLi-Fraumeni Syndrome (LFS) is a cancer predisposition syndrome characterized by the early-onset of multiple primary cancers which can occur at different moments (metachronous onset) or, more rarely, coincidentally (synchronous onset). Here we describe a previously unreported patient with presentation of synchronous Wilms tumor and Choroid...
Sosnowska-Sienkiewicz, Patrycja Gowin, Ewelina Jończyk-Potoczna, Katarzyna Mańkowski, Przemysław Godziński, Jan Januszkiewicz-Lewandowska, Danuta
Published in
International Journal of Environmental Research and Public Health
Patients with a Wilms tumor are often admitted to the hospital accidentally, with an abdominal mass causing asymmetry of the abdominal wall. Hypertension accompanying a Wilms tumor occurs in about 10–27% of children, but cardiomyopathy associated with a Wilms tumor is very rarely described. This publication presents a case of a 9-month-old girl wit...
Apple, Annie Lovvorn, Harold N. III
Published in
Frontiers in Oncology
Wilms tumor (WT) is the most common renal malignancy of childhood. Global disparities in WT have been reported with the highest incidence and lowest overall survival occurring in sub-Saharan African nations. After a detailed search of PubMed, we reviewed available literature on WT in sub-Saharan Africa and summarized findings that explore biologic ...
Bahoush, Gholamreza Pahlavani, Rozhin Salarinejad, Sareh Zarei, Elham
Published in
Radiology Case Reports
Botryoid Wilms tumors are intrapelvic polypoid masses that are uncommon feature of Wilms tumor. The authors reported a rare case of bilateral botryoid Wilms tumor in a 19-month-old boy who admitted to hospital with acute renal failure secondary to hydronephrosis caused by bilateral botryoid Wilms tumor with ureteral extension. The patient was succe...
Kitamura, Eiko Cowell, John K. Chang, Chang-Sheng Hawthorn, Lesleyann
Published in
Genes & Cancer
Background: Wilms tumor is the most common pediatric renal tumor and the fourth most common malignancy in children. Chromosome 16q deletion(del) or loss of heterozygosity (LOH) has been correlated with recurrence and overall poor prognosis, such that patients with 16qLOH and 1p allelic loss are treated with more aggressive chemotherapeutic regimens...
Lu, Meng-Yao Wang, Wen-Chung Hou, Tai-Cheng Kuo, Chen-Yun Lai, Yen-Chein
Published in
Pathology oncology research : POR
Wilms tumor is the most common pediatric renal malignancy. Several genetic loci have been shown to be associated with its formation. Genetic or epigenetic aberrations at WT1 and WT2 loci have been implicated in the etiology of the majority of sporadic Wilms tumors. In our previous study, most Wilms tumors tested negative for both constitutional mut...
Davis, Joseph T. Wagner, Lars M.
Published in
Translational Andrology and Urology
Urologic tumors make up approximately 10% of all pediatric cancers, and include a variety of different histologies and imaging considerations. In this review, we discuss standard radiologic approaches for children with tumors arising in the genitourinary system, and identify important ways in which imaging affects the differential diagnosis, preope...
Gillespie, Nali Julia Van Mater, David
Published in
Translational Andrology and Urology
Several hereditary cancer predisposition syndromes are associated with genitourinary (GU) manifestations in children. The GU manifestation may be the first symptom of a more global syndrome to arise, which places the pediatric urologist in a unique position to impact the health of the child. Some GU manifestations are pathognomonic for a particular...
Pater, Luke Melchior, Patrick Rübe, Christian Cooper, Benjamin T McAleer, Mary Fran Kalapurakal, John A Paulino, Arnold C
Published in
Pediatric blood & cancer
The objectives for the treatment of Wilms tumor in both the Children's Oncology Group (COG) and the International Society of Paediatric Oncology (SIOP) have focused on improving cure rates and minimizing toxicity by limiting the use of radiation and doxorubicin. Although the timing of surgery is different in COG (upfront surgery) and SIOP (upfront ...
Im, Jacob Soliman, Mohamed A R Alkhamees, Abdullah F Eaton, Sydney Quint, Elise Shahab, Saba O'Connor, Avalon Haberfellner, Erika Dyer, Erin
Published in
World neurosurgery
We report the first case of cervical spine chondrosarcoma in a Wilms tumor survivor. A 52-year-old female patient presented with myelopathic symptoms including poor balance, difficulty walking, and numbness of both feet. A magnetic resonance imaging of the spine showed a mass at the right C7-T1 foramen causing significant cord compression. The pati...
