Ben Hassena, Amal Haendiges, Julie Zormati, Sonia Guermazi, Sonda Gdoura, Radhouane Gonzalez-Escalona, Narjol Siala, Mariam
Published in
International journal of food microbiology
Whole genome sequencing (WGS) has made impressive progress in the field of molecular biology. Its most common application for public health is in the area of surveillance of food-borne diseases. WGS has the potential for providing a large amount of information, such as the identification of the strain type, the characterization of antibiotic resist...
Nzoyikorera, Néhémie Diawara, Idrissa Fresia, Pablo Maaloum, Fakhreddine Katfy, Khalid Nayme, Kaotar Maaloum, Mossaab Cornick, Jennifer Chaguza, Chrispin Timinouni, Mohammed
...
Published in
BMC Genomics
BackgroundStreptococcus pneumoniae serotype 1 remains a leading cause of invasive pneumococcal diseases, even in countries with PCV-10/PCV-13 vaccine implementation. The main objective of this study, which is part of the Pneumococcal African Genome project (PAGe), was to determine the phylogenetic relationships of serotype 1 isolates recovered from...
Qaiser, Farah Yin, Yue Mervis, Carolyn B. Morris, Colleen A. Klein-Tasman, Bonita P. Tam, Elaine Osborne, Lucy R. Yuen, Ryan K. C.
Published in
Orphanet Journal of Rare Diseases
Background7q11.23 duplication (Dup7) is one of the most frequent recurrent copy number variants (CNVs) in individuals with autism spectrum disorder (ASD), but based on gold-standard assessments, only 19% of Dup7 carriers have ASD, suggesting that additional genetic factors are necessary to manifest the ASD phenotype. To assess the contribution of a...
Mo, Xueyan Cai, Xinghua Hui, Qinyan Sun, Huijie Yu, Ran Bu, Ru Yan, Bing Ou, Qian Li, Quanwen He, Sheng
...
Published in
Microbial Cell Factories
BackgroundNerol (C10H18O), an acyclic monoterpene, naturally presents in plant essential oils, and is used widely in food, cosmetics and pharmaceuticals as the valuable fragrance. Meanwhile, chemical synthesis is the only strategy for large-scale production of nerol, and the disadvantages of chemical synthesis greatly limit the production and its a...
Hwang, Daekeun Kim, Seung Min Kim, Hyun Jung
Published in
Gut Pathogens
BackgroundAcid treatment is commonly used for controlling or killing pathogenic microorganisms on medical devices and environments; however, inadequate acid treatment may cause acid tolerance response (ATR) and offer cross-protection against environmental stresses, including antimicrobials. This study aimed to characterise an Escherichia coli strai...
Rossetti, Maria Lucia Almeida da Silva, Pedro Eduardo Salvato, Richard Steiner Reis, Ana Júlia Schiefelbein, Sun Hee von Groll, Andrea Barcellos, Regina Bones Maschmann, Raquel Esteves, Leonardo Souza Spies, Fernanda
...
Published in
Tuberculosis (Edinburgh, Scotland)
Here we described phenotypical, molecular and epidemiological features of a highly rifampicin-resistant Mycobacterium tuberculosis strain emerging in Southern Brazil, that carries an uncommon insertion of 12 nucleotides at the codon 435 in the rpoB gene. Employing a whole-genome sequencing-based study on drug-resistant Mycobacterium tuberculosis st...
Park, Ye-Lim Song, Hun-Suk Choi, Tae-Rim Lee, Sun Mi Park, Sol Lee Lee, Hye Soo Kim, Hyun-Joong Bhatia, Shashi Kant Gurav, Ranjit Park, Kyungmoon
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Published in
International journal of biological macromolecules
Poly(3-hydroxybutyrate) (PHB) is a common polyhydroxyalkanoate (PHA) with potential as an alternative for petroleum-based plastics. Previously, we reported a new strain, Halomonas sp. YLGW01, which hyperproduces PHB with 94% yield using fructose. In this study, we examined the PHB production machinery of Halomonas sp. YLGW01 in more detail by deep-...
Li, Jiyun Zhou, Yuqing Yang, Dawei Zhang, Shan Sun, Zhiliang Wang, Yang Wang, Shaolin Wu, Congming
Published in
Veterinary microbiology
The prevalence and antimicrobial susceptibility of Clostridium perfringens (C. perfringens) in chickens and pigs were investigated in Beijing and Shanxi, China. In total, 322 C. perfringens (chicken n = 60 and pig n = 262) were obtained from 620 feces of chickens (n = 256) and pigs (n = 364). Multiplex PCR for toxin typing of C. perfringens reveale...
Murata, Shiro Machida, Yuka Isezaki, Masayoshi Maekawa, Naoya Okagawa, Tomohiro Konnai, Satoru Ohashi, Kazuhiko
Published in
Virology Journal
BackgroundMarek’s disease virus (MDV) causes malignant lymphomas in chickens (Marek’s disease, MD). MD is currently controlled by vaccination; however, MDV strains have a tendency to develop increased virulence. Distinct diversity and point mutations are present in the Meq proteins, the oncoproteins of MDV, suggesting that changes in protein functi...
Kutilova, Iva Medvecky, Matej Leekitcharoenphon, Pimlapas Munk, Patrick Masarikova, Martina Davidova-Gerzova, Lenka Jamborova, Ivana Bortolaia, Valeria Pamp, Sünje J Dolejska, Monika
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Published in
Environmental research
Wastewaters serve as important hot spots for antimicrobial resistance and monitoring can be used to analyse the abundance and diversity of antimicrobial resistance genes at the level of large bacterial and human populations. In this study, whole genome sequencing of beta-lactamase-producing Escherichia coli and metagenomic analysis of whole-communi...
